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Sergey Brezgin

CRISPR-Cas systems for diagnosing infectious diseases
2021 · Anastasiya Kostyusheva, Sergey Brezgin, et al. · Methods · 202
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Dead Cas Systems: Types, Principles, and Applications
2019 · Sergey Brezgin, Anastasiya Kostyusheva, et al. · International Journal of Molecular Sciences · 136
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Host-cell interactions in HBV infection and pathogenesis: the emerging role of m6A modification
2021 · Anastasiya Kostyusheva, Sergey Brezgin, et al. · Emerging Microbes & Infections · 91
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Orthologous CRISPR/Cas9 systems for specific and efficient degradation of covalently closed circular DNA of hepatitis B virus
2019 · Dmitry Kostyushev, Sergey Brezgin, et al. · Cellular and Molecular Life Sciences · 90
Gene Editing by Extracellular Vesicles
2020 · Dmitry Kostyushev, Anastasiya Kostyusheva, et al. · International Journal of Molecular Sciences · 75
Biomimetic Nanoparticles for Basic Drug Delivery
2024 · Andrey Tikhonov, Artyom Kachanov, et al. · Pharmaceutics · 68
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Suppressing the NHEJ pathway by DNA-PKcs inhibitor NU7026 prevents degradation of HBV cccDNA cleaved by CRISPR/Cas9
2019 · Dmitry Kostyushev, Anastasiya Kostyusheva, et al. · Scientific Reports · 62
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Technological aspects of manufacturing and analytical control of biological nanoparticles
2023 · Sergey Brezgin, Alessandro Parodi, et al. · Biotechnology Advances · 60
Basic Guide for Approaching Drug Delivery with Extracellular Vesicles
2024 · Sergey Brezgin, Oleg Danilik, et al. · International Journal of Molecular Sciences · 50
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The menace of severe adverse events and deaths associated with viral gene therapy and its potential solution
2024 · Artyom Kachanov, Anastasiya Kostyusheva, et al. · Medicinal Research Reviews · 46
Biomimetic approaches for targeting tumor-promoting inflammation
2022 · Alessandro Parodi, Dmitry Kostyushev, et al. · Seminars in Cancer Biology · 35
Depleting hepatitis B virus relaxed circular DNA is necessary for resolution of infection by CRISPR-Cas9
2023 · Dmitry Kostyushev, Anastasiya Kostyusheva, et al. · Molecular Therapy — Nucleic Acids · 34
Clinical and Translational Landscape of Viral Gene Therapies
2024 · Alexandra Yudaeva, Anastasiya Kostyusheva, et al. · Cells · 30
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Immunity and Viral Infections: Modulating Antiviral Response via CRISPR–Cas Systems
2021 · Sergey Brezgin, Anastasiya Kostyusheva, et al. · Viruses · 28
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ATM and ATR Expression Potentiates HBV Replication and Contributes to Reactivation of HBV Infection upon DNA Damage
2019 · Anastasiya Kostyusheva, Sergey Brezgin, et al. · Viruses · 26
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Swelling, Rupture and Endosomal Escape of Biological Nanoparticles Per Se and Those Fused with Liposomes in Acidic Environment
2024 · Natalia Ponomareva, Sergey Brezgin, et al. · Pharmaceutics · 24
Small Molecular Inhibitors of DNA Double Strand Break Repair Pathways Increase the ANTI-HBV Activity of CRISPR/Cas9
2019 · A. P. Kostyusheva, D. S. Kostyushev, et al. · Molecular Biology · 24
Transient and tunable CRISPRa regulation of APOBEC/AID genes for targeting hepatitis B virus
2023 · Dmitry Kostyushev, Sergey Brezgin, et al. · Molecular Therapy — Nucleic Acids · 22
CRISPR Screening: Molecular Tools for Studying Virus–Host Interactions
2021 · Vladimir Chulanov, Anastasiya Kostyusheva, et al. · Viruses · 21
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Replenishment of Hepatitis B Virus cccDNA Pool Is Restricted by Baseline Expression of Host Restriction Factors In Vitro
2019 · Sergey Brezgin, Anastasiia Kostyusheva, et al. · Microorganisms · 21
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Proteolytic Resistance Determines Albumin Nanoparticle Drug Delivery Properties and Increases Cathepsin B, D, and G Expression
2023 · Ekaterina P. Kolesova, Vera S. Egorova, et al. · International Journal of Molecular Sciences · 20
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Низкомолекулярные ингибиторы путей репарации двухцепочечных разрывов ДНК усиливают противовирусное действие системы CRISPR/Cas9 на моделях вируса гепатита B
2019 · А. П. Костюшева, Д. С. Костюшев, et al. · Molecular Biology · 19
Hydroxychloroquine Enhances Cytotoxic Properties of Extracellular Vesicles and Extracellular Vesicle–Mimetic Nanovesicles Loaded with Chemotherapeutics
2023 · Sergey Brezgin, Anastasiya Kostyusheva, et al. · Pharmaceutics · 18
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Clinical Implications of Hepatitis B Virus RNA and Covalently Closed Circular DNA in Monitoring Patients with Chronic Hepatitis B Today with a Gaze into the Future: The Field Is Unprepared for a Sterilizing Cure
2018 · Anastasiya Kostyusheva, Dmitry Kostyushev, et al. · Genes · 18
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m6A Methylation in Regulation of Antiviral Innate Immunity
2024 · Ivan Karandashov, Anastasiya Kostyusheva, et al. · Viruses · 15
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Works count: 66
Citation count: 1,365
H-index: 20
I10-index: 29
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