Author

Eyup Akgün

Observed names: Akgün, Eyüp, E Akgün, E. Akgün, Eyup Akgün, Eyüp Akgün

Institutions: University of Minnesota, Kahramanmaraş Sütçü İmam University

Observed institutions: Gebze Technical University, University of Bern, University of Minnesota, Mayo Clinic, University of Kansas, Philipps University of Marburg, University of Pittsburgh, Johannes Gutenberg University Mainz, Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, University of Würzburg, Mayo Clinic in Arizona, Minneapolis VA Medical Center, Kahramanmaraş Sütçü İmam University

ORCID: 0000-0001-7571-169X

Observed ORCID: 0000-0001-7571-169X

OpenAlex ID: A5000305679

Ligands that interact with putative MOR-mGluR5 heteromer in mice with inflammatory pain produce potent antinociception

2013 · Eyup Akgün, Muhammad I. Javed, et al. · Proceedings of the National Academy of Sciences · 88

Bivalent Ligands That Target μ Opioid (MOP) and Cannabinoid1 (CB1) Receptors Are Potent Analgesics Devoid of Tolerance

2013 · Morgan Le Naour, Eyup Akgün, et al. · Journal of Medicinal Chemistry · 84

Mixed-ligand Copper(II) Complexes: Investigation of their Spectroscopic, Catalysis, Antimicrobial and Potentiometric Properties

2006 · Mehmet Tümer, Nihal Deligönül, et al. · Transition Metal Chemistry · 71

Combined Glia Inhibition and Opioid Receptor Agonism Afford Highly Potent Analgesics without Tolerance

2018 · Eyup Akgün, Mary M. Lunzer, et al. · ACS Chemical Neuroscience · 67

Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5)

2015 · Eyup Akgün, Muhammad I. Javed, et al. · Journal of Medicinal Chemistry · 59

Induced Association of μ Opioid (MOP) and Type 2 Cholecystokinin (CCK2) Receptors by Novel Bivalent Ligands

2008 · Yaguo Zheng, Eyup Akgün, et al. · Journal of Medicinal Chemistry · 59

Synthesis and characterization of Schiff base metal complexes: their antimicrobial, genotoxicity and electrochemical properties

2008 · Mehmet Tümer, Eyup Akgün, et al. · Journal of Coordination Chemistry · 57

Asymmetric synthesis of β-lactams and n-benzoyl-3-phenylisoserines via the staudinger reaction

1991 · Gunda I. Georg, Peter M. Mashava, et al. · Tetrahedron Letters · 47

Targeting putative mu opioid/metabotropic glutamate receptor-5 heteromers produces potent antinociception in a chronic murine bone cancer model

2014 · Branden A. Smeester, Mary M. Lunzer, et al. · European Journal of Pharmacology · 45

Reaktionen von elektronenreichen heterocyclen mit orthocarbonsäure‐derivaten. I. Zum reaktionsverhalten von acyclischen orthoestern mit indolen unter säurekatalyse

1983 · E. Akgün, U. Pindur, et al. · Journal of Heterocyclic Chemistry · 35

MDAN-21: A Bivalent Opioid Ligand Containing mu-Agonist and Delta-Antagonist Pharmacophores and Its Effects in Rhesus Monkeys

2012 · Mario D. Aceto, Louis S. Harris, et al. · International Journal of Medicinal Chemistry · 34

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Bivalent ligand that activates mu opioid receptor and antagonizes mGluR5 receptor reduces neuropathic pain in mice

2017 · Cristina D. Peterson, Kelley F. Kitto, et al. · Pain · 33

Rapid reduction of sulfones to sulfides using LiAlH 4 –TiCl 4

1994 · Eyup Akgün, Khalid Mahmood, et al. · Journal of the Chemical Society Chemical Communications · 33

Galactose-Imines in the staudinger reaction

1992 · Gunda I. Georg, Eyüp Akgün, et al. · Tetrahedron Letters · 32

A bivalent compound targeting CCR5 and the mu opioid receptor treats inflammatory arthritis pain in mice without inducing pharmacologic tolerance

2018 · Raini Dutta, Mary M. Lunzer, et al. · Arthritis Research & Therapy · 31

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A novel Schiff base: Synthesis, structural characterisation and comparative sensor studies for metal ion detections

2014 · Muhammet Köse, Savas Purtas, et al. · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · 30

Synthesis and in Vitro Characterization of Radioiodinatable Benzodiazepines Selective for Type 1 and Type 2 Cholecystokinin Receptors

2009 · Eyup Akgün, Meike Körner, et al. · Journal of Medicinal Chemistry · 29

Chemische eigenschaften und synthese‐verfahren von 3‐vinylindolen

1985 · E. Akgün, U. Pindur · Journal of Heterocyclic Chemistry · 27

Molecular Basis for Binding and Subtype Selectivity of 1,4-Benzodiazepine Antagonist Ligands of the Cholecystokinin Receptor

2012 · Erin E. Cawston, Polo C.H. Lam, et al. · Journal of Biological Chemistry · 25

Heteromer Induction: An Approach to Unique Pharmacology?

2017 · Philip S. Portoghese, Eyup Akgün, et al. · ACS Chemical Neuroscience · 24

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Combination of a δ-opioid Receptor Agonist and Loperamide Produces Peripherally-mediated Analgesic Synergy in Mice

2019 · Daniel J. Bruce, Cristina D. Peterson, et al. · Anesthesiology · 23

Reaktionen von elektronenreichen Heterocyclen mit Orthocarbonsäure‐Derivaten, 9. Acylierungsreaktionen von Indol und Methylindolen mit Dialkoxycarbenium‐tetrafluoroboraten

1986 · Ulf Pindur, Camran Flo, et al. · Liebigs Annalen der Chemie · 23

The bivalent ligand MCC22 potently attenuates hyperalgesia in a mouse model of cisplatin-evoked neuropathic pain without tolerance or reward

2019 · Giuseppe Cataldo, Samuel J. Erb, et al. · Neuropharmacology · 22

Synthesewege zu und synthetische Verwendung von 2-Vinylindolen

1985 · Eyüp Akgün, Ulf Pindur · CHIMIA International Journal for Chemistry · 19

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Modulation of Cell Surface Expression of Nonactivated Cholecystokinin Receptors Using Bivalent Ligand-Induced Internalization

2010 · Kaleeckal G. Harikumar, Eyup Akgün, et al. · Journal of Medicinal Chemistry · 17

Works count: 79

Citation count: 1,285

H-index: 22

I10-index: 36