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Jeffrey M. Chen
Observed names:
Jeffrey Chen,
Jeffrey M Chen,
Jeffrey M. Chen
Institutions:
University of Saskatchewan,
Vaccine and Infectious Disease Organization
Observed institutions:
Délégation Paris 5,
Dalhousie University,
University of Connecticut,
University of Toronto,
University of Saskatchewan,
Vaccine and Infectious Disease Organization,
École Polytechnique Fédérale de Lausanne
show all 7
ORCID:
0000-0001-8431-3802
Observed ORCID:
0000-0001-8431-3802
OpenAlex ID:
A5000375230
Roles of Lsr2 in Colony Morphology and Biofilm Formation ofMycobacterium smegmatis
2005
·
Jeffrey M. Chen
, Greg J. German
, et al.
·
Journal of Bacteriology
·
142
Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein
2012
·
Benjamin Blasco
, Jeffrey M. Chen
, et al.
·
PLoS Pathogens
·
137
PDF
Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein
2008
·
Jeffrey M. Chen
, Huiping Ren
, et al.
·
Nucleic Acids Research
·
105
Identification of the lipooligosaccharide biosynthetic gene cluster from Mycobacterium marinum
2007
·
Huiping Ren
, Lynn G. Dover
, et al.
·
Molecular Microbiology
·
105
PDF
Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion
2014
·
Jan Rybniker
, Jeffrey M. Chen
, et al.
·
Cell Host & Microbe
·
99
PDF
EspD Is Critical for the Virulence-Mediating ESX-1 Secretion System in Mycobacterium tuberculosis
2011
·
Jeffrey M. Chen
, Stefanie Boy-Röttger
, et al.
·
Journal of Bacteriology
·
82
M ycobacterium tuberculosis EspB binds phospholipids and mediates EsxA ‐independent virulence
2013
·
Jeffrey M. Chen
, Ming Zhang
, et al.
·
Molecular Microbiology
·
74
ESAT-6 Secretion-Independent Impact of ESX-1 Genes espF and espG1 on Virulence of Mycobacterium tuberculosis
2011
·
Daria Bottai
, Laleh Majlessi
, et al.
·
The Journal of Infectious Diseases
·
74
PDF
Differential productions of lipid virulence factors among BCG vaccine strains and implications on BCG safety
2007
·
Jeffrey M. Chen
, Salim T. Islam
, et al.
·
Vaccine
·
67
PimF, a Mannosyltransferase of Mycobacteria, Is Involved in the Biosynthesis of Phosphatidylinositol Mannosides and Lipoarabinomannan
2004
·
David C. Alexander
, Joses R.W. Jones
, et al.
·
Journal of Biological Chemistry
·
62
A Point Mutation in cycA Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium bovis BCG Vaccine Strains
2012
·
Jeffrey M. Chen
, Swapna Uplekar
, et al.
·
PLoS ONE
·
57
PDF
Site-directed Mutagenesis of Acyl Carrier Protein (ACP) Reveals Amino Acid Residues Involved in ACP Structure and Acyl-ACP Synthetase Activity
2001
·
Anathea S. Flaman
, Jeffrey M. Chen
, et al.
·
Journal of Biological Chemistry
·
55
Mycobacterium bovis BCG Vaccines Exhibit Defects in Alanine and Serine Catabolism
2003
·
Jeffrey M. Chen
, David C. Alexander
, et al.
·
Infection and Immunity
·
52
The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron–sulfur cluster biogenesis and oxidative stress defence
2014
·
Jan Rybniker
, Florence Pojer
, et al.
·
Biochemical Journal
·
51
Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate with Attenuation of Virulence
2013
·
Jeffrey M. Chen
, Ming Zhang
, et al.
·
Journal of Bacteriology
·
51
PDF
Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis
2010
·
Jeffrey M. Chen
, Florence Pojer
, et al.
·
Drug Discovery Today Disease Mechanisms
·
31
EspI regulates the ESX ‐1 secretion system in response to ATP levels in M ycobacterium tuberculosis
2014
·
Ming Zhang
, Jeffrey M. Chen
, et al.
·
Molecular Microbiology
·
29
Mycobacterium tuberculosis EspK Has Active but Distinct Roles in the Secretion of EsxA and EspB
2022
·
Ze Long Lim
, Kylee Drever
, et al.
·
Journal of Bacteriology
·
22
Sigma Factor F Does Not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis
2010
·
Ruben C. Hartkoorn
, Claudia Sala
, et al.
·
Journal of Bacteriology
·
15
Domestic pigs experimentally infected with Mycobacterium bovis and Mycobacterium tuberculosis exhibit different disease outcomes
2022
·
Nirajan Niroula
, Ze Long Lim
, et al.
·
Tuberculosis
·
14
PDF
Pyrazole and Triazole Derivatives as Mycobacterium tuberculosis UDP-Galactopyranose Inhibitors
2022
·
Dalia M. Ahmed
, Jeffrey M. Chen
, et al.
·
Pharmaceuticals
·
12
PDF
Mycosins of the Mycobacterial Type VII ESX Secretion System: the Glue That Holds the Party Together
2016
·
Jeffrey M. Chen
·
mBio
·
10
PDF
Protein Synthesis and Degradation Inhibitors Potently Block Mycobacterium tuberculosis type-7 Secretion System ESX-1 Activity
2021
·
Kylee Drever
, Ze Long Lim
, et al.
·
ACS Infectious Diseases
·
9
Orally administered live BCG and heat-inactivated Mycobacterium bovis protect bison against experimental bovine tuberculosis
2025
·
Nirajan Niroula
, Priya Ghodasara
, et al.
·
Scientific Reports
·
6
PDF
A SNP in the Cache 1 Signaling Domain of Diguanylate Cyclase STM1987 Leads to Increased In Vivo Fitness of Invasive Salmonella Strains
2021
·
Akosiererem S. Sokaribo
, Lindsay R. Balezantis
, et al.
·
Infection and Immunity
·
6
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Works count:
35
Citation count:
1,377
H-index:
18
I10-index:
22
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