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Jason R. Dobson

Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases
2016 · Ying-Nan P. Chen, Matthew J. LaMarche, et al. · Nature · 905
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes
2014 · Mark D M Leiserson, Fabio Vandin, et al. · Nature Genetics · 905
A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas
2016 · Jeffrey R. Infante, Philippe A. Cassier, et al. · Clinical Cancer Research · 317
Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine
2014 · Benjamin J Raphael, Jason R Dobson, et al. · Genome Medicine · 218
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Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-Based Subtypes
2017 · Li Zhang, Kenzie D. MacIsaac, et al. · Molecular Cancer Research · 201
Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells
2008 · Jitesh Pratap, John J. Wixted, et al. · Cancer Research · 191
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A Phase I Study of the CDK4/6 Inhibitor Ribociclib (LEE011) in Pediatric Patients with Malignant Rhabdoid Tumors, Neuroblastoma, and Other Solid Tumors
2017 · Birgit Geoerger, Franck Bourdeaut, et al. · Clinical Cancer Research · 190
Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours
2021 · Jordi Rodon, Guillem Argilés, et al. · British Journal of Cancer · 176
Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis
2014 · Hai Wu, Troy W Whitfield, et al. · Genome biology · 147
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The BRG1 chromatin remodeling enzyme links cancer cell metabolism and proliferation
2016 · Qiong Wu, Pasil Madany, et al. · Oncotarget · 74
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Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition
2017 · Deli Hong, Terri L. Messier, et al. · Oncotarget · 66
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The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation
2015 · Qiong Wu, Pasil Madany, et al. · Journal of Cellular Physiology · 63
Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motility
2010 · David T Leong, Joleen Lim, et al. · Breast Cancer Research · 63
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Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation
2016 · Guray Kuzu, Emily G. Kaye, et al. · PLoS Genetics · 56
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hsa-mir-30c promotes the invasive phenotype of metastatic breast cancer cells by targeting NOV/CCN3
2014 · Jason R Dobson, Hanna Taipaleenmäki, et al. · Cancer Cell International · 49
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Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes
2010 · Syed A. Ali, Sayyed K. Zaidi, et al. · Proceedings of the National Academy of Sciences · 44
A Runx2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation
2012 · Sayed A. Ali, Jason R. Dobson, et al. · Journal of Cell Science · 37
The bone-specific Runx2-P1 promoter displays conserved three-dimensional chromatin structure with the syntenic Supt3h promoter
2014 · A. Rasim Barutcu, Phillip W. L. Tai, et al. · Nucleic Acids Research · 31
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Expression of the IL‐11 Gene in Metastatic Cells Is Supported by Runx2‐Smad and Runx2‐cJun Complexes Induced by TGFβ1
2015 · Xuhui Zhang, Hai Wu, et al. · Journal of Cellular Biochemistry · 30
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Identifying Nuclear Matrix‐Attached DNA Across the Genome
2016 · Jason R. Dobson, Deli Hong, et al. · Journal of Cellular Physiology · 22
Abstract 5324: Pan-cancer identification of mutated pathways and protein complexes
2014 · Mark D. Leiserson, Fabio Vandin, et al. · Cancer Research · 16
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one
2016 · Andreas Lundqvist, Vincent van Hoef, et al. · Journal for ImmunoTherapy of Cancer · 11
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Abstract CT175: Biomarker analyses from a phase I study of WNT974, a first-in-class Porcupine inhibitor, in patients (pts) with advanced solid tumors
2018 · Jordi Rodon, Guillem Argilés, et al. · Cancer Research · 10
A phase 1/2a study of GEN-009, a neoantigen vaccine based on autologous peptide immune responses.
2019 · Roger B. Cohen, Melissa Lynne Johnson, et al. · Journal of Clinical Oncology · 5
Abstract P4-22-12: Ribociclib + fulvestrant in postmenopausal women with HR+, HER2– advanced breast cancer (ABC)
2017 · SM Tolaney, A Forero-Torres, et al. · Cancer Research · 4
Works count: 61
Citation count: 3,834
H-index: 20
I10-index: 23
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