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Björn Glinghammar

Deoxycholic acid causes DNA damage in colonic cells with subsequent induction of caspases, COX-2 promoter activity and the transcription factors NF-kB and AP-1
2002 · B. Glinghammar · Carcinogenesis · 133
Keratin‐18 and micro RNA ‐122 complement alanine aminotransferase as novel safety biomarkers for drug‐induced liver injury in two human cohorts
2013 · Petra Thulin, Gunnar Nordahl, et al. · Liver International · 123
Isoforms of alanine aminotransferases in human tissues and serum—Differential tissue expression using novel antibodies
2007 · Per Lindblom, Ingalill Rafter, et al. · Archives of Biochemistry and Biophysics · 107
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
2022 · Nadilly Bonagas, Nina M. S. Gustafsson, et al. · Nature Cancer · 101
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Shift from a dairy product-rich to a dairy product-free diet: influence on cytotoxicity and genotoxicity of fecal water--potential risk factors for colon cancer
1997 · B Glinghammar, M Venturi, et al. · American Journal of Clinical Nutrition · 91
PPARδ activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells
2003 · Bjorn Glinghammar, Josefin Skogsberg, et al. · Biochemical and Biophysical Research Communications · 80
Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytes
2014 · Anna-Karin M. Sjogren, Maria Liljevald, et al. · Archives of Toxicology · 77
Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa
2023 · Andrej Emanuel Cotman, Martina Durcik, et al. · Journal of Medicinal Chemistry · 68
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PPARα regulates the hepatotoxic biomarker alanine aminotransferase (ALT1) gene expression in human hepatocytes
2008 · Petra Thulin, Ingalill Rafter, et al. · Toxicology and Applied Pharmacology · 68
Bile Acid Concentrations, Cytotoxicity, and pH of Fecal Water from Patients with Colorectal Adenomas
1999 · T. M. C. M. De Kok, A. Van Faassen, et al. · Digestive Diseases and Sciences · 68
Colonic luminal contents induce cyclooxygenase 2 transcription in human colon carcinoma cells
2001 · Bjorn Glinghammar, Joseph Rafter · Gastroenterology · 66
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A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran
2009 · Ulf Andersson, Johan Lindberg, et al. · Biomarkers · 50
Effects of colonic lumenal components on AP-1-dependent gene transcription in cultured human colon carcinoma cells
1999 · B. Glinghammar · Carcinogenesis · 50
Prediction of drug-induced liver injury in humans by using in vitro methods: The case of ximelagatran
2007 · Kerstin Kenne, Inger Skanberg, et al. · Toxicology in Vitro · 49
New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus
2023 · Martina Durcik, Andrej Emanuel Cotman, et al. · Journal of Medicinal Chemistry · 42
A longitudinal assessment of miR-122 and GLDH as biomarkers of drug-induced liver injury in the rat
2016 · Petra Thulin, Robert J. Hornby, et al. · Biomarkers · 42
Effect of Colonic Luminal Components on Induction of Apoptosis in Human Colonic Cell Lines
2000 · Ana I. Haza, Bjorn Glinghammar, et al. · Nutrition and Cancer · 38
Differential expression of peroxisomal proliferator activated receptors α and δ in skeletal muscle in response to changes in diet and exercise
2006 · Katja Kannisto, Alexander Chibalin, et al. · International Journal of Molecular Medicine · 35
Isoform-specific alanine aminotransferase measurement can distinguish hepatic from extrahepatic injury in humans
2012 · INGALILL RAFTER, TRULS GRÅBERG, et al. · International Journal of Molecular Medicine · 33
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hERG-toxicity prediction using traditional machine learning and advanced deep learning techniques
2023 · Erik Ylipää, Swapnil Chavan, et al. · Current Research in Toxicology · 31
Effects on Cell Proliferation, Activator Protein-1 and Genotoxicity by Fecal Water from Patients with Colorectal Adenomas
2003 · M. M. Nordling, B. Glinghammar, et al. · Scandinavian Journal of Gastroenterology · 27
Carcinogenesis in the colon
1999 · B Glinghammar, J Rafter · European Journal of Cancer Prevention · 23
Interactions between the environment and genes in the colon
1998 · Joseph Rafter, Bjorn Glinghammar · European Journal of Cancer Prevention · 20
PPARδ increases expression of the human apolipoprotein A-II gene in human liver cells
2008 · Petra Thulin, Björn Glinghammar, et al. · International Journal of Molecular Medicine · 12
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Proliferative and Molecular Effects of the Dual PPARα/γ Agonist Tesaglitazar in Rat Adipose Tissues: Relevance for Induction of Fibrosarcoma
2011 · Björn Glinghammar, Anna-Lena Berg, et al. · Toxicologic Pathology · 6
Works count: 34
Citation count: 1,449
H-index: 22
I10-index: 24
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