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Iakov N. Rudenko

Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
2014 · Alexandria Beilina, Iakov N. Rudenko, et al. · Proceedings of the National Academy of Sciences · 357
Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation
2014 · Guoxiang Liu, Jia Yu, et al. · Journal of Clinical Investigation · 166
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mRNA expression, splicing and editing in the embryonic and adult mouse cerebral cortex
2013 · Allissa A Dillman, David N Hauser, et al. · Nature Neuroscience · 148
The G2385R variant of leucine-rich repeat kinase 2 associated with Parkinson's disease is a partial loss-of-function mutation
2012 · Iakov N. Rudenko, Alice Kaganovich, et al. · Biochemical Journal · 120
Phosphorylation of LRRK2 by casein kinase 1α regulates trans-Golgi clustering via differential interaction with ARHGEF7
2014 · Ruth Chia, Sara Haddock, et al. · Nature Communications · 103
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Hexokinase activity is required for recruitment of parkin to depolarized mitochondria
2013 · Melissa K. McCoy, Alice Kaganovich, et al. · Human Molecular Genetics · 97
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Identification of protein phosphatase 1 as a regulator of the LRRK2 phosphorylation cycle
2013 · Evy Lobbestael, Jing Zhao, et al. · Biochemical Journal · 96
Is Inhibition of Kinase Activity the Only Therapeutic Strategy for LRRK2-associated Parkinson's Disease?
2012 · Iakov N Rudenko, Ruth Chia, et al. · BMC Medicine · 64
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Heterogeneity of Leucine-Rich Repeat Kinase 2 Mutations: Genetics, Mechanisms and Therapeutic Implications
2014 · Iakov N. Rudenko, Mark R. Cookson · Neurotherapeutics · 55
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Proteomic analysis reveals co-ordinated alterations in protein synthesis and degradation pathways in LRRK2 knockout mice
2018 · Laura Pellegrini, David N Hauser, et al. · Human Molecular Genetics · 54
The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2
2017 · Iakov N. Rudenko, Alice Kaganovich, et al. · Biochemical Journal · 38
The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research
2016 · Rebekah G. Langston, Iakov N. Rudenko, et al. · Biochemical Journal · 28
14-3-3 proteins are promising LRRK2 interactors
2010 · Iakov N. Rudenko, Mark R. Cookson · Biochemical Journal · 23
Differences in Stability, Activity and Mutation Effects Between Human and Mouse Leucine-Rich Repeat Kinase 2
2018 · Rebekah G. Langston, Iakov N. Rudenko, et al. · Neurochemical Research · 19
Effects of lithium on isolated rat heart mitochondria
2010 · S. M. Korotkov, V. P. Nesterov, et al. · Doklady Biochemistry and Biophysics · 2
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2021 · I. S. Savka, S. A. Sapa, et al. · Current aspects of military medicine Сучасні аспекти військової медицини
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Works count: 16
Citation count: 1,370
H-index: 14
I10-index: 14
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