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Mann‐Jen Hour
Observed names:
Hour, Mann-Jen,
MANN-JEN HOUR,
Mann-Jen Hour,
Mann-Jen 侯曼貞Hour,
Mann‑Jen Hour
Institutions:
China Medical University,
China Medical University Beigang Hospital,
China Medical University
Observed institutions:
University of North Carolina at Chapel Hill,
China Medical University,
China Medical University Beigang Hospital,
China Medical University Hospital,
National Cancer Institute,
Shin Kong WHS Memorial Hospital,
China Medical University
show all 7
ORCID:
0000-0001-6714-8788
Observed ORCID:
0000-0001-6714-8788
OpenAlex ID:
A5001128007
6-Alkylamino- and 2,3-Dihydro-3‘-methoxy-2-phenyl-4-quinazolinones and Related Compounds: Their Synthesis, Cytotoxicity, and Inhibition of Tubulin Polymerization
2000
·
Mann-Jen Hour
, Li-Jiau Huang
, et al.
·
Journal of Medicinal Chemistry
·
411
Antitumor Agents. Part 204: Synthesis and Biological Evaluation of Substituted 2-Aryl Quinazolinones
2001
·
Yi Xia
, Zheng-Yu Yang
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
208
Synthesis of 4-alkoxy-2-phenylquinoline derivatives as potent antiplatelet agents
2001
·
Ting-Chia Ko
, Mann-Jen Hour
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
95
MJ-29 Inhibits Tubulin Polymerization, Induces Mitotic Arrest, and Triggers Apoptosis via Cyclin-Dependent Kinase 1-Mediated Bcl-2 Phosphorylation in Human Leukemia U937 Cells
2010
·
Jai-Sing Yang
, Mann-Jen Hour
, et al.
·
Journal of Pharmacology and Experimental Therapeutics
·
92
5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts
2014
·
Han-Ching Lin
, Tzu-Hung Lin
, et al.
·
PLoS ONE
·
70
PDF
Curcumin-loaded nanoparticles enhance apoptotic cell death of U2OS human osteosarcoma cells through the Akt-Bad signaling pathway
2013
·
SHU-FEN PENG
, CHAO-YING LEE
, et al.
·
International Journal of Oncology
·
68
PDF
Novel Quinazolinone MJ-29 Triggers Endoplasmic Reticulum Stress and Intrinsic Apoptosis in Murine Leukemia WEHI-3 Cells and Inhibits Leukemic Mice
2012
·
Chi-Cheng Lu
, Jai-Sing Yang
, et al.
·
PLoS ONE
·
66
PDF
Protection of dopaminergic neurons by 5-lipoxygenase inhibitor
2013
·
Kai-Hsiang Kang
, Horng-Hui Liou
, et al.
·
Neuropharmacology
·
58
Photodynamic activity of aloe-emodin induces resensitization of lung cancer cells to anoikis
2010
·
Hong-Zin Lee
, Wen-Hui Yang
, et al.
·
European Journal of Pharmacology
·
55
Baicalein, Ethyl Acetate, and Chloroform Extracts ofScutellaria baicalensisInhibit the Neuraminidase Activity of Pandemic 2009 H1N1 and Seasonal Influenza A Viruses
2013
·
Mann-Jen Hour
, Su-Hua Huang
, et al.
·
Evidence-based Complementary and Alternative Medicine
·
48
PDF
Glycyrrhetinic acid derivatives as Zika virus inhibitors: Synthesis and antiviral activity in vitro
2021
·
Lidia A. Baltina
, Hsueh-Chou Lai
, et al.
·
Bioorganic & Medicinal Chemistry
·
47
Newly synthesized quinazolinone HMJ-38 suppresses angiogenetic responses and triggers human umbilical vein endothelial cell apoptosis through p53-modulated Fas/death receptor signaling
2013
·
Jo-Hua Chiang
, Jai-Sing Yang
, et al.
·
Toxicology and Applied Pharmacology
·
47
Novel quinazolinone MJ‑33 induces AKT/mTOR‑mediated autophagy‑associated apoptosis in 5FU‑resistant colorectal cancer cells
2020
·
Hai‑Anh Ha
, Jo‑Hua Chiang
, et al.
·
Oncology Reports
·
45
PDF
Tubacin, an HDAC6 Selective Inhibitor, Reduces the Replication of the Japanese Encephalitis Virus via the Decrease of Viral RNA Synthesis
2017
·
Chien-Yi Lu
, Yi-Chih Chang
, et al.
·
International Journal of Molecular Sciences
·
44
PDF
Cell death caused by quinazolinone HMJ-38 challenge in oral carcinoma CAL 27 cells: dissections of endoplasmic reticulum stress, mitochondrial dysfunction and tumor xenografts
2014
·
Chi-Cheng Lu
, Jai-Sing Yang
, et al.
·
Biochimica et Biophysica Acta (BBA) - General Subjects
·
44
Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells
2012
·
MANN-JEN HOUR
, SHIH-CHANG TSAI
, et al.
·
International Journal of Oncology
·
41
PDF
Selective induction of G2/M arrest and apoptosis in HL-60 by a potent anticancer agent, HMJ-38.
2004
·
Jai-Sing Yang
, Mann-Jen Hour
, et al.
·
PubMed
·
39
SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling
2017
·
Ching-Ying Wang
, Chien-Yi Lu
, et al.
·
Virus Research
·
35
PDF
Novel quinazoline HMJ‐30 induces U‐2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up‐regulation of ATM/p53 signaling pathway
2011
·
Yu‐Jen Chiu
, Mann‐Jen Hour
, et al.
·
Journal of Orthopaedic Research®
·
35
PDF
Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthase
2019
·
Bang-Jau You
, Mann-Jen Hour
, et al.
·
Scientific Reports
·
31
PDF
Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents
2012
·
Xiao-Feng Wang
, Xing-Tao Tian
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
31
Chaperones are the target in aloe-emodin-induced human lung nonsmall carcinoma H460 cell apoptosis
2007
·
Miao-Ying Lai
, Mann-Jen Hour
, et al.
·
European Journal of Pharmacology
·
31
Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells
2013
·
HUI-JYE CHEN
, YI-LIN JIANG
, et al.
·
International Journal of Oncology
·
30
PDF
Antiviral activity of glycyrrhizic acid conjugates with amino acid esters against Zika virus
2020
·
Lidia A. Baltina
, Mann-Jen Hour
, et al.
·
Virus Research
·
29
MJ-66 induces malignant glioma cells G2/M phase arrest and mitotic catastrophe through regulation of cyclin B1/Cdk1 complex
2014
·
Wei-Ting Liu
, Ching Chen
, et al.
·
Neuropharmacology
·
27
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Works count:
67
Citation count:
2,084
H-index:
25
I10-index:
43
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