Author

Colin Kwok

Observed names: C. Kwok, Colin J. Kwok, Kwok, C.

Institution: Institute of Cancer Research

Observed institutions: Royal Marsden NHS Foundation Trust, Institute of Cancer Research, King's College London, University of Hong Kong, Birkbeck, University of London

ORCID: 0000-0001-8312-7215

Observed ORCID: 0000-0001-8312-7215

OpenAlex ID: A5001379166

Combined MYC and P53 Defects Emerge at Medulloblastoma Relapse and Define Rapidly Progressive, Therapeutically Targetable Disease

2014 · Rebecca M. Hill, Sanne Kuijper, et al. · Cancer Cell · 210

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Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

2017 · Gabriele Büchel, Anne Carstensen, et al. · Cell Reports · 103

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Recruitment of RXR by Homotetrameric RARα Fusion Proteins Is Essential for Transformation

2007 · Bernd B. Zeisig, Colin Kwok, et al. · Cancer Cell · 91

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Orally bioavailable CDK9/2 inhibitor shows mechanism-based therapeutic potential in MYCN-driven neuroblastoma

2020 · Evon Poon, Tong Liang, et al. · Journal of Clinical Investigation · 67

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Forced homo-oligomerization of RARα leads to transformation of primary hematopoietic cells

2006 · Colin Kwok, Bernd B. Zeisig, et al. · Cancer Cell · 64

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In Vivo Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis

2019 · Orli Yogev, Gilberto S. Almeida, et al. · Cancer Research · 63

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Transforming activity of AML1-ETO is independent of CBFβ and ETO interaction but requires formation of homo-oligomeric complexes

2009 · Colin Kwok, Bernd B. Zeisig, et al. · Proceedings of the National Academy of Sciences · 47

G6PDdb, an integrated database of glucose-6-phosphate dehydrogenase (G6PD) mutations

2002 · Colin J. Kwok, Andrew C.R. Martin, et al. · Human Mutation · 41

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MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

2020 · David King, Xiao Dun Li, et al. · Oncotarget · 37

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Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells

2023 · Y. Sbirkov, T. Schenk, et al. · Frontiers in Cell and Developmental Biology · 16

Semi-Quantitative Mass Spectrometry in AML Cells Identifies New Non-Genomic Targets of the EZH2 Methyltransferase

2017 · Yordan Sbirkov, Colin Kwok, et al. · International Journal of Molecular Sciences · 11

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The role of CBFβ in AML1-ETO's activity

2010 · Colin Kwok, Bernd B. Zeisig, et al. · Blood · 9

The biguanide polyamine analog verlindamycin promotes differentiation in neuroblastoma via induction of antizyme

2021 · Zuzanna Urban-Wójciuk, Amy Graham, et al. · Cancer Gene Therapy · 4

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Analysis of pigeon intestinal mucin allergens using a novel dot blot assay

2000 · Christopher I Baldwin, Jane E Calvert, et al. · Carbohydrate Research · 4

MIF-CD74 signaling drives immune modulation in medulloblastoma

2026 · Benjamin Draper, Zhen You, et al. · Neuro-Oncology · 2

Correction: MYCN expression induces replication stress and sensitivity to PARP inhibition in neuroblastoma

2023 · David King, Xiao Dun Li, et al. · Oncotarget · 2

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The role of CBF beta in AML1-ETO's activity. (vol 115, pg 3176, 2010)

2010 · Kwok, C., Zeisig, B. B., et al. · Research Portal (King's College London) · 1

ID #555 Small molecule drug screening, chemoinformatics and integrative transcriptomics identify targetable MYC-dependent therapeutic vulnerabilities in high-risk medulloblastoma

2026 · Louisa Taylor, Beth Poole, et al. · Neuro-Oncology Pediatrics

Mdb-66. High-throughput Small Molecule Drug Screening, Transcriptomics and Integrative Ai Identify Targetable Myc-dependent Therapeutic Vulnerabilities in High-risk Medulloblastoma

2024 · Gemma Llargués-Sistac, Louisa Taylor, et al. · Neuro-Oncology

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Data from In Vivo Modeling of Chemoresistant Neuroblastoma Provides New Insights into Chemorefractory Disease and Metastasis