Get started
Author

Hector Esquer

Observed names: Esquer, Hector, Esquer, Hector J., Esquer, Hector Jose, Hector J. Esquer
ORCID: 0000-0002-1911-1523
Observed ORCID: 0000-0002-1911-1523
OpenAlex ID: A5001795152
Sense and Release: A Thiol-Responsive Flavonol-Based Photonically Driven Carbon Monoxide-Releasing Molecule That Operates via a Multiple-Input AND Logic Gate
2017 · Livia S. Lazarus, Hector J. Esquer, et al. · Journal of the American Chemical Society · 135
A Structurally‐Tunable 3‐Hydroxyflavone Motif for Visible Light‐Induced Carbon Monoxide‐Releasing Molecules (CORMs)
2015 · Stacey N. Anderson, Jason M. Richards, et al. · ChemistryOpen · 134
PDF
Mitochondrial-Localized Versus Cytosolic Intracellular CO-Releasing Organic PhotoCORMs: Evaluation of CO Effects Using Bioenergetics
2018 · Livia S. Lazarus, Hector J. Esquer, et al. · ACS Chemical Biology · 47
First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer
2020 · Joshua M. Abbott, Qiong Zhou, et al. · Molecular Cancer Therapeutics · 27
Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer
2021 · Hector Esquer, Qiong Zhou, et al. · Oncogene · 24
Advanced High-Content-Screening Applications of Clonogenicity in Cancer
2020 · Hector Esquer, Qiong Zhou, et al. · SLAS DISCOVERY · 20
Drug Design Targeting T‑Cell Factor-Driven Epithelial–Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer
2019 · Adedoyin D. Abraham, Hector Esquer, et al. · Journal of Medicinal Chemistry · 18
Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L
2022 · Brett J. Prigaro, Hector Esquer, et al. · Journal of Medicinal Chemistry · 17
Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21
2022 · Kendra M. Prutton, John O. Marentette, et al. · Free Radical Biology and Medicine · 13
The validation of new CHD1L inhibitors as a therapeutic strategy for cancer
2023 · Sophia Clune, Paul Awolade, et al. · Biomedicine & Pharmacotherapy · 7
Targeted Inhibition of CHD1L by OTI-611 Reprograms Chemotherapy and Targeted Therapy-Induced Cell Cycle Arrest and Suppresses Proliferation to Produce Synergistic Antitumor Effects in Breast and Colorectal Cancer
2025 · Hector Esquer, Qiong Zhou, et al. · Cells · 6
HTS discovery of PARP1-HPF1 complex inhibitors in cancer
2023 · Timothy Kellett, Rida Noor, et al. · SLAS DISCOVERY · 6
PDF
High-Content Drug Discovery Targeting Molecular Bladder Cancer Subtypes
2022 · Sébastien Rinaldetti, Qiong Zhou, et al. · International Journal of Molecular Sciences · 6
PDF
CHD1L Regulates Cell Survival in Breast Cancer and Its Inhibition by OTI-611 Impedes the DNA Damage Response and Induces PARthanatos
2024 · Rita Sala, Hector Esquer, et al. · International Journal of Molecular Sciences · 5
CHD1L Inhibitor OTI-611 Synergizes with Chemotherapy to Enhance Antitumor Efficacy and Prolong Survival in Colorectal Cancer Mouse Models
2024 · Rita Sala, Hector Esquer, et al. · International Journal of Molecular Sciences · 4
Breast cancer cell coculture induces normal lung fibroblast transition to CAFs, promoting tumor cell dormancy and therapy resistance
2025 · Marika L. Klosowski, Kathryn E. Cronise, et al. · Proceedings of the National Academy of Sciences · 3
CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential
2025 · Sophia Clune, Paul Awolade, et al. · Journal of Experimental & Clinical Cancer Research · 3
PDF
Trisomy 21 cerebral organoids exhibit Alzheimer’s disease amyloid and apolipoprotein E co-pathologies
2026 · Breanna R. Dooling, Anne Vielle, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
PDF
Glycolytic and redox control of neuronal excitability in vitro
2018 · Christopher Huynh, Hector Esquer, et al. · Free Radical Biology and Medicine · 1
Lactosylceramides Impair Cardiomyocyte Function in Hypoplastic Left Heart Syndrome
2026 · Praveen Ramaswamy, Mary Turner, et al. · Journal of Molecular and Cellular Cardiology Plus
Apolipoprotein E4 contributes to Alzheimer’s disease neuropathology in Down syndrome
2024 · Breanna Dooling, Rose Summers, et al. · Alzheimer s & Dementia
PDF
Abstract LB317: TNBC cell co-culture with primary human lung fibroblasts identifies a paracrine-juxtacrine signaling loop promoting fibroblast activation and autophagy-dependent breast cancer cell therapy resistance
2024 · Marika L. Klosowski, Kathryn Cronise, et al. · Cancer Research
Supplementary Data from First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer
2023 · Joshua M. Abbott, Qiong Zhou, et al.
PDF
Supplementary Data from First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer
2023 · Joshua M. Abbott, Qiong Zhou, et al.
Data from First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer
2023 · Joshua M. Abbott, Qiong Zhou, et al.
Works count: 36
Citation count: 478
H-index: 9
I10-index: 9
Year
Topic
Type