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Xavier Michelet
Observed names:
Michelet X,
X. Michelet
Observed institutions:
Université Paris-Sud,
Brigham and Women's Hospital,
Centre National de la Recherche Scientifique,
Harvard University,
Agenus (United States),
Centre de Génétique Moléculaire,
MiNK Therapeutics (United States)
show all 7
ORCID:
0000-0003-0334-4231
Observed ORCID:
0000-0003-0334-4231
OpenAlex ID:
A5001895446
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
2018
·
Xavier Michelet
, Lydia Dyck
, et al.
·
Nature Immunology
·
647
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue
2014
·
Lydia Lynch
, Xavier Michelet
, et al.
·
Nature Immunology
·
403
Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity
2017
·
Selma Boulenouar
, Xavier Michelet
, et al.
·
Immunity
·
207
PDF
A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair
2016
·
Marisa Encarnação
, Lília Espada
, et al.
·
The Journal of Cell Biology
·
112
PDF
The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans
2010
·
Adriana Alberti
, Xavier Michelet
, et al.
·
Autophagy
·
100
PDF
Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell–mediated cytotoxicity
2013
·
Amit Tuli
, Jerome Thiery
, et al.
·
Molecular Biology of the Cell
·
75
Human Granzyme K Is a Feature of Innate T Cells in Blood, Tissues, and Tumors, Responding to Cytokines Rather than TCR Stimulation
2023
·
Danielle Duquette
, Cathal Harmon
, et al.
·
The Journal of Immunology
·
59
Induction of autophagy in ESCRT mutants is an adaptive response for cell survival in C. elegans
2012
·
Abderazak Djeddi
, Xavier Michelet
, et al.
·
Journal of Cell Science
·
58
Stromal cell cadherin-11 regulates adipose tissue inflammation and diabetes
2017
·
Sook Kyung Chang
, Ayano C. Kohlgruber
, et al.
·
Journal of Clinical Investigation
·
57
PDF
ALDH7A1 inhibits the intracellular transport pathways during hypoxia and starvation to promote cellular energy homeostasis
2019
·
Jia-Shu Yang
, Jia-Wei Hsu
, et al.
·
Nature Communications
·
56
PDF
Developmental and cellular functions of the ESCRT machinery in pluricellular organisms
2010
·
Xavier Michelet
, Abderazak Djeddi
, et al.
·
Biology of the Cell
·
49
PDF
A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome
2024
·
Terese C. Hammond
, Marco A. Purbhoo
, et al.
·
Nature Communications
·
48
PDF
MHC Class II Presentation Is Controlled by the Lysosomal Small GTPase, Arl8b
2015
·
Xavier Michelet
, Salil Garg
, et al.
·
The Journal of Immunology
·
48
Glutathione transferases kappa 1 and kappa 2 localize in peroxisomes and mitochondria, respectively, and are involved in lipid metabolism and respiration in Caenorhabditis elegans
2009
·
Elise Petit
, Xavier Michelet
, et al.
·
FEBS Journal
·
48
Lysosome-Mediated Plasma Membrane Repair Is Dependent on the Small GTPase Arl8b and Determines Cell Death Type in Mycobacterium tuberculosis Infection
2018
·
Xavier Michelet
, Amit Tuli
, et al.
·
The Journal of Immunology
·
36
The ESCRT‐III protein CeVPS‐32 is enriched in domains distinct from CeVPS‐27 and CeVPS‐23 at the endosomal membrane of epithelial cells
2009
·
Xavier Michelet
, Adriana Alberti
, et al.
·
Biology of the Cell
·
29
PDF
Molecular mechanism of phosphopeptide neoantigen immunogenicity
2023
·
Yury Patskovsky
, Aswin Natarajan
, et al.
·
Nature Communications
·
22
PDF
Abstract CT275: Phase 1 clinical update of allogeneic invariant natural killer T cells (iNKTs), agenT-797, alone or in combination with pembrolizumab or nivolumab in patients with advanced solid tumors
2023
·
Benedito Carneiro
, Benjamin Garmezy
, et al.
·
Cancer Research
·
13
The ESCRT-II proteins are involved in shaping the sarcoplasmic reticulum in C. elegans
2016
·
Christophe Lefebvre
, Céline Largeau
, et al.
·
Journal of Cell Science
·
12
PDF
470 Botensilimab, an Fc-enhanced CTLA-4 antibody, enhances innate and adaptive immune activation to promote superior anti-tumor immunity in cold and I-O refractory tumors
2022
·
Chloe Delepine
, Daniel Levey
, et al.
·
Journal for ImmunoTherapy of Cancer
·
11
PDF
Autophagy in endosomal mutants
2012
·
Xavier Michelet
, Renaud Legouis
·
Worm
·
11
PDF
The Allogeneic FAP-CAR-IL15 iNKT Therapy MiNK-215 Remodels the Tumor Stroma to Enhance Antitumor Immunity
2025
·
Eleni Chantzoura
, Efrat Altman-Sharoni
, et al.
·
Cancer Immunology Research
·
4
Abstract 1878: Fc-enhanced anti-CTLA-4 antibody, AGEN1181: new mechanistic insights for potent antitumor immunity and combination potential in treatment-resistant solid tumors
2021
·
Antoine J. Tanne
, Claire Galand
, et al.
·
Cancer Research
·
4
649 Phase 1/2 study of AgenT-797, an allogeneic invariant natural killer T (iNKT) cell therapy, in subjects with moderate to severe acute respiratory distress syndrome (ARDS) secondary to SARS-CoV-2 (COVID-19)
2022
·
Marco Purbhoo
, Burcu Yigit
, et al.
·
Journal for ImmunoTherapy of Cancer
·
3
PDF
164 AgenT-797, a novel allogenic and ‘off-the shelf’ iNKT cell therapy promotes effective tumor killing
2020
·
Burcu Yigit
, Xavier Michelet
, et al.
·
Journal for ImmunoTherapy of Cancer
·
3
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Works count:
58
Citation count:
2,122
H-index:
17
I10-index:
21
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