Get started
Author

Frederick J. Sheedy

Observed names: F J Sheedy, F. J. Sheedy, F.J. Sheedy, Fred J. Sheedy, Fred Sheedy, Frederick J Sheedy, Frederick Sheedy, Frederick J. Sheedy, Sheedy, Frederick
Observed institutions: University College Dublin, King's College London, Trinity College Dublin, NYU Langone Health, St. James's Hospital, New York University, University of Birmingham
ORCID: 0000-0003-2645-8493
Observed ORCIDs: 0000-0003-2645-8493, 0000-0002-4722-3135
OpenAlex ID: A5003275100
Macrophages in atherosclerosis: a dynamic balance
2013 · Kathryn J. Moore, Frederick J. Sheedy, et al. · Nature reviews. Immunology · 2,625
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
2015 · Eva M. Palsson-McDermott, Anne M. Curtis, et al. · Cell Metabolism · 1,431
PDF
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
2009 · Frederick J Sheedy, Eva Palsson-McDermott, et al. · Nature Immunology · 1,027
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
2013 · Frederick J Sheedy, Alena Grebe, et al. · Nature Immunology · 965
MicroRNAs: the fine-tuners of Toll-like receptor signalling
2011 · Luke A. O'Neill, Frederick J. Sheedy, et al. · Nature reviews. Immunology · 881
Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
2011 · Katey J. Rayner, Christine C. Esau, et al. · Nature · 710
Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
2011 · Katey J. Rayner, Frederick J. Sheedy, et al. · Journal of Clinical Investigation · 702
Turning 21: Induction of miR-21 as a Key Switch in the Inflammatory Response
2015 · Frederick J. Sheedy · Frontiers in Immunology · 511
PDF
MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis
2015 · Mireille Ouimet, Hasini N. Ediriweera, et al. · Journal of Clinical Investigation · 393
PDF
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism
2016 · Mireille Ouimet, Stefan Koster, et al. · Nature Immunology · 365
Cutting Edge: Mycobacterium tuberculosis Induces Aerobic Glycolysis in Human Alveolar Macrophages That Is Required for Control of Intracellular Bacillary Replication
2016 · Laura E Gleeson, Frederick J Sheedy, et al. · The Journal of Immunology · 320
PDF
Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity
2014 · Bhama Ramkhelawon, Elizabeth J Hennessy, et al. · Nature Medicine · 278
IL-10 Inhibits miR-155 Induction by Toll-like Receptors
2010 · Claire E. McCoy, Frederick J. Sheedy, et al. · Journal of Biological Chemistry · 265
Adding fuel to fire: microRNAs as a new class of mediators of inflammation
2008 · F J Sheedy, L A J O'Neill · Annals of the Rheumatic Diseases · 247
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
2015 · Eva M. Palsson-McDermott, Anne M. Curtis, et al. · Cell Metabolism · 205
PDF
Mycobacterium tuberculosis Limits Host Glycolysis and IL-1β by Restriction of PFK-M via MicroRNA-21
2020 · Emer E. Hackett, Hugo Charles-Messance, et al. · Cell Reports · 174
PDF
Regulating metabolic inflammation by nutritional modulation
2020 · Hugo Charles-Messance, Kathleen A.J. Mitchelson, et al. · Journal of Allergy and Clinical Immunology · 119
Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses
2022 · Mimmi L. E. Lundahl, Morgane Mitermite, et al. · eLife · 90
Metabolic reprogramming & inflammation: Fuelling the host response to pathogens
2016 · Laura E. Gleeson, Frederick J. Sheedy · Seminars in Immunology · 76
von Willebrand factor links primary hemostasis to innate immunity
2022 · Clive Drakeford, Sonia Aguila, et al. · Nature Communications · 70
PDF
Recognition of yeast β-glucan particles triggers immunometabolic signaling required for trained immunity
2024 · Cian J.H. Horneck Johnston, Anna E. Ledwith, et al. · iScience · 69
The Troll in Toll: Mal and Tram as bridges for TLR2 and TLR4 signaling
2007 · Frederick J Sheedy, Luke A J O’Neill · Journal of Leukocyte Biology · 67
IL-1 signaling in atherosclerosis: sibling rivalry
2013 · Frederick J Sheedy, Kathryn J Moore · Nature Immunology · 66
PDF
Toll-like Receptor-4 (TLR4) Down-regulates MicroRNA-107, Increasing Macrophage Adhesion via Cyclin-dependent Kinase 6
2011 · Elizabeth J. Hennessy, Frederick J. Sheedy, et al. · Journal of Biological Chemistry · 65
PDF
Targeting immunometabolism in host defence against Mycobacterium tuberculosis
2020 · Frederick J. Sheedy, Maziar Divangahi · Immunology · 62
PDF
Works count: 57
Citation count: 12,210
H-index: 32
I10-index: 36
Year
Topic
Type