Product
Help
Pricing
About
Jobs
Log in
Get started
Author
Add to collection
Martina Nibbio
Observed name:
M. Nibbio
Institution:
IRBM
Observed institutions:
Siena Biotech (Italy),
Novartis (Italy),
IRBM
ORCID:
0000-0002-2905-3689
Observed ORCID:
0000-0002-2905-3689
OpenAlex ID:
A5003336792
Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand
2020
·
Longbin Liu
, Michael E. Prime
, et al.
·
Journal of Medicinal Chemistry
·
46
Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems
2016
·
Alessandra Guidi
, Cristiana Lalli
, et al.
·
PLoS neglected tropical diseases
·
29
PDF
Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors
2023
·
Esther Torrente
, Valentina Fodale
, et al.
·
ACS Medicinal Chemistry Letters
·
27
PDF
[11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins
2021
·
Longbin Liu
, Peter D. Johnson
, et al.
·
Journal of Medicinal Chemistry
·
27
Use of ‘dilute-and-shoot’ liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma
2015
·
Simone Esposito
, Elena Bracacel
, et al.
·
Journal of Pharmaceutical and Biomedical Analysis
·
19
Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway
2015
·
Arianna Nencini
, Carmela Pratelli
, et al.
·
European Journal of Medicinal Chemistry
·
19
Discovery of a Novel Series of Potent SHP2 Allosteric Inhibitors
2023
·
Alessia Petrocchi
, Alessandro Grillo
, et al.
·
ACS Medicinal Chemistry Letters
·
16
PDF
5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein
2020
·
Savina Malancona
, Mattia Mori
, et al.
·
ACS Medicinal Chemistry Letters
·
10
An allosteric inhibitor of the Zika virus NS2B-NS3 protease with oral efficacy in mouse models
2026
·
Jesus M. Ontoria
, Esther Torrente
, et al.
·
Nature Communications
·
6
PDF
Brain penetration assessment in vivo: A reliable and simple method in anesthetized rats at steady state
2014
·
Claus A. Andersen
, Paolo Perfetti
, et al.
·
Journal of Neuroscience Methods
·
5
Identification and in vitro characterization of a new series of potent and highly selective G9a inhibitors as novel anti-fibroadipogenic agents
2022
·
Pietro Randazzo
, Roberta Sinisi
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
4
Novel azabicyclic series of potent SHP2 allosteric inhibitors
2025
·
Alessio Sferrazza
, Ilaria Rossetti
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
2
Discovery and Preclinical Characterization of I-0436650, a Selective SHP2 Allosteric Inhibitor for RAS-Driven Cancers
2026
·
Alina Ciammaichella
, Francesca Puca
, et al.
·
Journal of Medicinal Chemistry
Abstract 5614: Advancing treatment for brain tumors and metastases with brain permeable SHP2 inhibitor I-1000233
2025
·
Francesca Puca
, Alina Ciammaichella
, et al.
·
Cancer Research
Abstract 1975: Discovery of I-1000233, a potent, selective and brain permeable SHP2 allosteric inhibitor
2024
·
Francesca Puca
, Danilo Fabbrini
, et al.
·
Cancer Research
Discovery of I-0436650, a potent and selective SHP2 allosteric inhibitor for the treatment of RAS driven solid tumors
2022
·
F. Puca
, V. Fodale
, et al.
·
European Journal of Cancer
PDF
Show more works
View as search
Works count:
16
Citation count:
210
H-index:
8
I10-index:
8
Year
Topic
Type