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Author

Frank Hirth

Observed names: F. Hirth, Hirth, Frank
Observed institutions: Roche (Switzerland), University of London, King's College London, University of Basel, University of Zurich, UK Dementia Research Institute, Medical Research Council
ORCID: 0000-0001-8581-9450
Observed ORCID: 0000-0001-8581-9450
OpenAlex ID: A5003473254
Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
2013 · Youn-Bok Lee, Han-Jou Chen, et al. · Cell Reports · 496
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Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease
2018 · Jessika C. Bridi, Frank Hirth · Frontiers in Neuroscience · 381
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Deep Homology of Arthropod Central Complex and Vertebrate Basal Ganglia
2013 · Nicholas J. Strausfeld, Frank Hirth · Science · 354
Evolution of Nervous Systems
2007 · Frank Hirth, Heinrich Reichert · 341
Thebrain tumorgene negatively regulates neural progenitor cell proliferation in the larval central brain ofDrosophila
2006 · Bruno Bello, Heinrich Reichert, et al. · Development · 276
Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation
2021 · Paraskevi Tziortzouda, Ludo Van Den Bosch, et al. · Nature reviews. Neuroscience · 267
Drosophila melanogaster in the Study of Human Neurodegeneration
2010 · Frank Hirth · CNS & Neurological Disorders - Drug Targets · 236
A Pulse of the Drosophila Hox Protein Abdominal-A Schedules the End of Neural Proliferation via Neuroblast Apoptosis
2003 · Bruno C. Bello, Frank Hirth, et al. · Neuron · 204
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An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila
2003 · Frank Hirth, Lars Kammermeier, et al. · Development · 202
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Developmental defects in brain segmentation caused by mutations of the homeobox genes orthodenticle and empty spiracles in Drosophila
1995 · Frank Hirth, Stavros Therianos, et al. · Neuron · 200
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Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
2013 · Danielle C. Diaper, Yoshitsugu Adachi, et al. · Human Molecular Genetics · 159
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Conserved genetic programs in insect and mammalian brain development
1999 · Frank Hirth, Heinrich Reichert · BioEssays · 143
The Dopaminergic System in the Aging Brain of Drosophila
2010 · Katherine E. White, Dickon M. Humphrey, et al. · Frontiers in Neuroscience · 139
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Homeotic gene action in embryonic brain development of Drosophila
1998 · Frank Hirth, Beate Hartmann, et al. · Development · 132
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Conserved genetic programs in insect and mammalian brain development
1999 · Frank Hirth, Heinrich Reichert · BioEssays · 114
Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila
1998 · Sandra Leuzinger, Frank Hirth, et al. · Development · 109
A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration
2018 · Daniel A Solomon, Alan Stepto, et al. · Brain · 100
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Embryonic development of the Drosophila brain: formation of commissural and descending pathways
1995 · Stavros Therianos, Sandra Leuzinger, et al. · Development · 98
C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
2017 · Youn-Bok Lee, Pranetha Baskaran, et al. · Human Molecular Genetics · 90
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Differential expression and function of the Drosophila Pax6 genes eyeless and twin of eyeless in embryonic central nervous system development
2001 · Lars Kammermeier, Ronny Leemans, et al. · Mechanisms of Development · 84
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Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD
2013 · Danielle C. Diaper, Yoshitsugu Adachi, et al. · Human Molecular Genetics · 81
Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila
2012 · Dickon M. Humphrey, Richard B. Parsons, et al. · Human Molecular Genetics · 71
Evolutionarily conserved mechanisms for the selection and maintenance of behavioural activity
2015 · Vincenzo G. Fiore, Raymond J. Dolan, et al. · Philosophical Transactions of the Royal Society B Biological Sciences · 66
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Quantitative transcript imaging in normal and heat-shocked Drosophila embryos by using high-density oligonucleotide arrays
2000 · Ronny Leemans, Boris Egger, et al. · Proceedings of the National Academy of Sciences · 66
TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila
2013 · Lies Vanden Broeck, Marina Naval-Sánchez, et al. · Cell Reports · 65
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Works count: 115
Citation count: 5,649
H-index: 38
I10-index: 60
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