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David W. Parkin
Observed names:
D W Parkin,
D.W. Parkin,
David W Parkin,
David. W. Parkin
Institution:
Adelphi University
Observed institutions:
Fox Chase Cancer Center,
Albert Einstein College of Medicine,
Pennsylvania State University,
University of Dundee,
Yeshiva University,
Chestnut Hill College,
Industrial Research Limited,
International Livestock Research Institute,
Adelphi University,
Temple University
show all 10
ORCID:
0000-0003-4479-3164
Observed ORCID:
0000-0003-4479-3164
OpenAlex ID:
A5003762466
Transition-state analysis of nucleoside hydrolase from Crithidia fasciculata
1991
·
Benjamin A. Horenstein
, David W. Parkin
, et al.
·
Biochemistry
·
135
Nucleoside hydrolase from Crithidia fasciculata. Metabolic role, purification, specificity, and kinetic mechanism.
1991
·
D.W. Parkin
, B.A. Horenstein
, et al.
·
Journal of Biological Chemistry
·
129
Transition-state structures for N-glycoside hydrolysis of AMP by acid and by AMP nucleosidase in the presence and absence of allosteric activator
1987
·
Frank Mentch
, David W. Parkin
, et al.
·
Biochemistry
·
112
Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax11Edited by R. Huber
2001
·
W. Versées
, K. Decanniere
, et al.
·
Journal of Molecular Biology
·
97
Purine-specific Nucleoside N-Ribohydrolase from Trypanosoma brucei brucei
1996
·
David W. Parkin
·
Journal of Biological Chemistry
·
92
Synthesis of nucleotides with specific radiolabels in ribose. Primary 14C and secondary 3H kinetic isotope effects on acid-catalyzed glycosidic bond hydrolysis of AMP, dAMP, and inosine.
1984
·
D W Parkin
, H B Leung
, et al.
·
Journal of Biological Chemistry
·
80
Molecular characterisation of mitochondrial and cytosolic trypanothione-dependent tryparedoxin peroxidases in Trypanosoma brucei
2001
·
Emmanuel Tetaud
, Christiane Giroud
, et al.
·
Molecular and Biochemical Parasitology
·
78
Iminoribitol Transition State Analogue Inhibitors of Protozoan Nucleoside Hydrolases
1999
·
Robert W. Miles
, Peter C. Tyler
, et al.
·
Biochemistry
·
78
A kinetic isotope effect study and transition state analysis of the S-adenosylmethionine synthetase reaction.
1987
·
G.D. Markham
, D.W. Parkin
, et al.
·
Journal of Biological Chemistry
·
59
Catalytic and allosteric mechanism of AMP nucleosidase from primary, .beta.-secondary, and multiple heavy atom kinetic isotope effects
1987
·
David W. Parkin
, Vern L. Schramm
·
Biochemistry
·
57
Molecular Cloning and Expression of a Purine-specific N-Ribohydrolase from Trypanosoma brucei brucei
1998
·
Roger Pellé
, Vern L. Schramm
, et al.
·
Journal of Biological Chemistry
·
56
PDF
Mechanistic Diagnoses of N-Ribohydrolases and Purine Nucleoside Phosphorylase
1996
·
L. John Mazzella
, David W. Parkin
, et al.
·
Journal of the American Chemical Society
·
52
Isozyme-Specific Transition State Inhibitors for the Trypanosomal Nucleoside Hydrolases
1997
·
David. W. Parkin
, Gerrit Limberg
, et al.
·
Biochemistry
·
41
Transition-state analysis of a Vmax mutant of AMP nucleosidase by the application of heavy-atom kinetic isotope effects
1991
·
David W. Parkin
, Frank Mentch
, et al.
·
Biochemistry
·
39
Binding modes for substrate and a proposed transition-state analog of protozoan nucleoside hydrolase
1995
·
David W. Parkin
, Vern L. Schramm
·
Biochemistry
·
34
Identification of proton-pump inhibitor drugs that inhibit Trichomonas vaginalis uridine nucleoside ribohydrolase
2014
·
Tara A. Shea
, Paola J. Burburan
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
31
Effects of allosteric activation on the primary and secondary kinetic isotope effects for three AMP nucleosidases.
1984
·
D W Parkin
, V L Schramm
·
Journal of Biological Chemistry
·
25
Promoting Nursing Students’ Chemistry Success in a Collegiate Active Learning Environment: “If I Have Hope, I Will Try Harder”
2018
·
Andri L. Smith
, Jean R. Paddock
, et al.
·
Journal of Chemical Education
·
23
Structure and Mechanism of the 6-Oxopurine Nucleosidase from Trypanosoma brucei brucei,
2010
·
An Vandemeulebroucke
, Claudia Minici
, et al.
·
Biochemistry
·
22
Druggability of the guanosine/adenosine/cytidine nucleoside hydrolase from Trichomonas vaginalis
2018
·
Rayyan Alam
, Allen T. Barbarovich
, et al.
·
Chemical Biology & Drug Design
·
13
Adenosine/guanosine preferring nucleoside ribohydrolase is a distinct, druggable antitrichomonal target
2015
·
Sierra Beck
, Samantha N. Muellers
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
12
Ligand-Efficient Inhibitors of Trichomonas vaginalis Adenosine/Guanosine Preferring Nucleoside Ribohydrolase
2019
·
Samantha N. Muellers
, Juliana A. Gonzalez
, et al.
·
ACS Infectious Diseases
·
8
Synthesis of nucleotides with specific radiolabels in ribose
1984
·
David W. Parkin
, Hazel B. Leung
, et al.
·
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
·
7
Discovery of Ligand-Efficient Scaffolds for the Design of Novel Trichomonas vaginalis Uridine Nucleoside Ribohydrolase Inhibitors Using Fragment Screening
2019
·
Shannon Auletta
, Wagma Caravan
, et al.
·
ACS Omega
·
6
Exploring Power Distribution and Its Influence on the Process of Argumentation in a POGIL Biochemistry Classroom
2018
·
Annabel N. Prince
, Wesley B. Pitts
, et al.
·
The journal of college science teaching
·
6
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Works count:
37
Citation count:
1,296
H-index:
19
I10-index:
21
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