Author

Chong Qin

Institutions: Ministry of Education of the People's Republic of China, Peking University, Qingdao National Laboratory for Marine Science and Technology, Marine Biomedical Research Institute of Qingdao, State Key Laboratory of Natural and Biomimetic Drugs, Ocean University of China

Observed institutions: Ministry of Education of the People's Republic of China, Chinese Academy of Sciences, Peking University, University of South Florida, University of Michigan, Qingdao National Laboratory for Marine Science and Technology, Michigan Medicine, Marine Biomedical Research Institute of Qingdao, U-M Rogel Cancer Center, State Key Laboratory of Organometallic Chemistry, State Key Laboratory of Natural and Biomimetic Drugs, Ocean University of China

ORCID: 0000-0001-8108-1698

Observed ORCID: 0000-0001-8108-1698

OpenAlex ID: A5004008030

Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer

2019 · Xin Han, Chao Wang, et al. · Journal of Medicinal Chemistry · 382

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

2018 · Chong Qin, Yang Hu, et al. · Journal of Medicinal Chemistry · 265

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Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands

2019 · Xin Han, Lijie Zhao, et al. · Journal of Medicinal Chemistry · 210

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Iron-Facilitated Direct Oxidative C−H Transformation of Allylarenes or Alkenes to Alkenyl Nitriles

2010 · Chong Qin, Ning Jiao · Journal of the American Chemical Society · 198

Silver‐Catalyzed Nitrogenation of Alkynes: A Direct Approach to Nitriles through CC Bond Cleavage

2013 · Tao Shen, Teng Wang, et al. · Angewandte Chemie International Edition · 185

Ru(ii)-catalyzed intermolecular C–H amidation of weakly coordinating ketones

2013 · Qing-Zhong Zheng, Yu-Feng Liang, et al. · Chemical Communications · 152

Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

2021 · Weiguo Xiang, Lijie Zhao, et al. · Journal of Medicinal Chemistry · 143

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Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer

2021 · Xin Han, Lijie Zhao, et al. · Journal of Medicinal Chemistry · 139

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Iron‐Catalyzed CH and CC Bond Cleavage: A Direct Approach to Amides from Simple Hydrocarbons

2011 · Chong Qin, Wang Zhou, et al. · Angewandte Chemie International Edition · 136

Small-molecule PROTAC degraders of the Bromodomain and Extra Terminal (BET) proteins — A review

2019 · Chao-Yie Yang, Chong Qin, et al. · Drug Discovery Today Technologies · 121

Identification of lipopeptides in Bacillus megaterium by two-step ultrafiltration and LC–ESI–MS/MS

2016 · Yunxiao Ma, Qing Kong, et al. · AMB Express · 109

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Selective CCsp Bond Cleavage: The Nitrogenation of Alkynes to Amides

2013 · Chong Qin, Peng Feng, et al. · Angewandte Chemie International Edition · 102

Implanting Nitrogen into Hydrocarbon Molecules through CH and CC Bond Cleavages: A Direct Approach to Tetrazoles

2011 · Feng Chen, Chong Qin, et al. · Angewandte Chemie International Edition · 95

FeCl2‐Promoted Cleavage of the Unactivated CC Bond of Alkylarenes and Polystyrene: Direct Synthesis of Arylamines

2012 · Chong Qin, Tao Shen, et al. · Angewandte Chemie International Edition · 86

Splitting a Substrate into Three Parts: Gold‐Catalyzed Nitrogenation of Alkynes by CC and CC Bond Cleavage

2015 · Chong Qin, Yijin Su, et al. · Angewandte Chemie International Edition · 79

Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer

2023 · Weiguo Xiang, Lijie Zhao, et al. · Journal of Medicinal Chemistry · 63

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Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer

2023 · Xin Han, Lijie Zhao, et al. · Journal of Medicinal Chemistry · 61

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PROTAC Degraders of Androgen Receptor‐Integrated Dissolving Microneedles for Androgenetic Alopecia and Recrudescence Treatment via Single Topical Administration

2022 · Ruxuan Wang, Tengjiang Zhong, et al. · Small Methods · 56

Silver‐Catalyzed Nitrogenation of Alkynes: A Direct Approach to Nitriles through CC Bond Cleavage

2013 · Tao Shen, Teng Wang, et al. · Angewandte Chemie · 49

Iron‐Catalyzed CH and CC Bond Cleavage: A Direct Approach to Amides from Simple Hydrocarbons

2011 · Chong Qin, Wang Zhou, et al. · Angewandte Chemie · 46

Discovery of BWA-522, a First-in-Class and Orally Bioavailable PROTAC Degrader of the Androgen Receptor Targeting N-Terminal Domain for the Treatment of Prostate Cancer

2023 · Bowen Zhang, Chang Liu, et al. · Journal of Medicinal Chemistry · 42

Implanting Nitrogen into Hydrocarbon Molecules through CH and CC Bond Cleavages: A Direct Approach to Tetrazoles

2011 · Feng Chen, Chong Qin, et al. · Angewandte Chemie · 37

Novel Sulfonylurea-Based NLRP3 Inflammasome Inhibitor for Efficient Treatment of Nonalcoholic Steatohepatitis, Endotoxic Shock, and Colitis

2023 · Zhuoyue Li, Yiming Chen, et al. · Journal of Medicinal Chemistry · 36

Precise Conformational Control Yielding Highly Potent and Exceptionally Selective BRD4 Degraders with Strong Antitumor Activity

2023 · Jiantao Hu, Biao Hu, et al. · Journal of Medicinal Chemistry · 30

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Selective CCsp Bond Cleavage: The Nitrogenation of Alkynes to Amides

2013 · Chong Qin, Peng Feng, et al. · Angewandte Chemie · 28

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Works count: 66

Citation count: 3,081

H-index: 26

I10-index: 37