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Len Reyno
Institution:
C4 Therapeutics (United States)
Observed institution:
C4 Therapeutics (United States)
OpenAlex ID:
A5004366341
A phase 1a dose-escalation study of PY314, a TREM2 (Triggering Receptor Expressed on Macrophages 2) targeting monoclonal antibody.
2022
·
Amita Patnaik
, Erika P. Hamilton
, et al.
·
Journal of Clinical Oncology
·
17
A phase 1a dose-escalation study of PY159, a monoclonal antibody targeting TREM1 (triggering receptor expressed on myeloid cells 1).
2023
·
Ira Seth Winer
, Amita Patnaik
, et al.
·
Journal of Clinical Oncology
·
3
PDF
Abstract LB071: Tuning the tumor myeloid microenvironment (TME) by targeting TREM2+ tumor-associated macrophages to overcome resistance to immune checkpoint inhibitors
2021
·
Nadine S. Jahchan
, Mikhail Binnewies
, et al.
·
Cancer Research
·
3
Safety of the BRD9 heterobifunctional degrader CFT8634 in synovial sarcoma and SMARCB1-null tumors: an open-label, dose-escalation, phase 1 clinical trial
2026
·
Brian A. Van Tine
, William D. Tap
, et al.
·
Communications Medicine
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Works count:
4
Citation count:
23
H-index:
3
I10-index:
1
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