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Jennie Roberts

Observed name: Roberts, Jennie
ORCID: 0000-0001-7372-8498
Observed ORCID: 0000-0001-7372-8498
OpenAlex ID: A5004463995
Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation
2022 · Nancy Gudgeon, Haydn Munford, et al. · Cell Reports · 79
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Proline synthesis through PYCR1 is required to support cancer cell proliferation and survival in oxygen-limiting conditions
2022 · Rebecca L. Westbrook, Esther Bridges, et al. · Cell Reports · 76
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Loss of SDHB Promotes Dysregulated Iron Homeostasis, Oxidative Stress, and Sensitivity to Ascorbate
2021 · Judith Goncalves, Sophie Moog, et al. · Cancer Research · 67
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TNF-α signals through ITK-Akt-mTOR to drive CD4 + T cell metabolic reprogramming, which is dysregulated in rheumatoid arthritis
2024 · Emma L. Bishop, Nancy Gudgeon, et al. · Science Signaling · 49
NAD Depletion Mediates Cytotoxicity in Human Neurons With Autophagy Deficiency
2022 · Congxin Sun, Elena Seranova, et al. · Cell Reports · 43
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A framework for tracer-based metabolism in mammalian cells by NMR
2019 · Raquel Saborano, Zuhal Eraslan, et al. · Scientific Reports · 41
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Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4- d ]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N 2-(2-Ethoxy-4-(4-methyl-4 H -1,2,4-triazol-3-yl)phenyl)-6-methyl- N 8-neopentylpyrido[3,4- d ]pyrimidine-2,8-diamine (BOS172722)
2018 · Hannah L. Woodward, Paolo Innocenti, et al. · Journal of Medicinal Chemistry · 33
LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells
2024 · Federica Cuozzo, Katrina Viloria, et al. · Cell Reports · 31
Rapid Discovery of Pyrido[3,4- d ]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach
2016 · Paolo Innocenti, Hannah L. Woodward, et al. · Journal of Medicinal Chemistry · 31
Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell
2022 · Louise S. Matheson, Georg Petkau, et al. · Scientific Reports · 27
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Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells
2025 · Megan R. Teh, Nancy Gudgeon, et al. · Nature Communications · 19
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1,25‐Dihydroxyvitamin D3 suppresses CD4 + T‐cell effector functionality by inhibition of glycolysis
2022 · Emma L. Bishop, Nancy H. Gudgeon, et al. · Immunology · 19
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Quantitative Isotopomer Rates in Real‐Time Metabolism of Cells Determined by NMR Methods
2019 · Michelle A. C. Reed, Jennie Roberts, et al. · ChemBioChem · 17
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Residual Complex I activity and amphidirectional Complex II operation support glutamate catabolism through mtSLP in anoxia
2024 · Dora Ravasz, David Bui, et al. · Scientific Reports · 16
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Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2
2021 · Eamon Fitzgerald, Jennie Roberts, et al. · Scientific Reports · 15
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Optimised collection of non‐uniformly sampled 2D‐HSQC NMR spectra for use in metabolic flux analysis
2020 · Mark Jeeves, Jennie Roberts, et al. · Magnetic Resonance in Chemistry · 12
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The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival
2024 · Vesna S. Stanulović, Shorog Al Omair, et al. · Haematologica · 8
Achieving human brain exposure with the oral ataxia-telangiectasia mutated kinase inhibitor AZD1390, a substrate of aldehyde oxidase
2025 · Nicola Colclough, Alexandra L. Orton, et al. · Drug Metabolism and Disposition · 5
Capillary Microsampling of Mouse Blood in Early Pre-Clinical Studies: A Preferred Alternative to Dried Blood Spot Sampling
2016 · Jennie Roberts, Ian Wilson, et al. · Journal of Bioanalysis & Biomedicine · 5
VHL-deficiency leads to reductive stress in renal cells
2023 · Hans Vellama, Kattri-Liis Eskla, et al. · Free Radical Biology and Medicine · 4
Intracrine FFA4 signaling controls lipolysis at lipid droplets
2025 · Shannon L. O’Brien, Emma Tripp, et al. · Nature Chemical Biology · 3
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Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy
2022 · Natividad Alquezar-Artieda, Daniela Kuzilkova, et al. · Blood Advances · 3
A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets
2023 · Emma Tripp, Shannon L. O’Brien, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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High-resolution glucose tracing and in situ imaging reveals regulated lactate production in human pancreatic β cells
2022 · Federica Cuozzo, Katrina Viloria, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2
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Golgi-localised Guanylate-binding protein 5 enhances glycolysis in macrophages
2026 · Samuel Lara-Reyna, Barbara Clough, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 1
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Works count: 48
Citation count: 613
H-index: 15
I10-index: 16
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