Author

Stephan Hellwig

Observed names: Hellwig, S., Hellwig, Stephan, S Hellwig, S. Hellwig

Institution: Fraunhofer Institute for Molecular Biology and Applied Ecology

Observed institutions: Fraunhofer Institute for Molecular Biology and Applied Ecology, RWTH Aachen University

OpenAlex ID: A5004518957

Plant cell cultures for the production of recombinant proteins

2004 · Stephan Hellwig, Jürgen Drossard, et al. · Nature Biotechnology · 587

GMP issues for recombinant plant-derived pharmaceutical proteins

2011 · Rainer Fischer, Stefan Schillberg, et al. · Biotechnology Advances · 229

Towards molecular farming in the future: using plant‐cell‐suspension cultures as bioreactors

1999 · Rainer Fischer, Neil Emans, et al. · Biotechnology and Applied Biochemistry · 130

Analysis of single-chain antibody production in Pichia pastoris using on-line methanol control in fed-batch and mixed-feed fermentations.

2001 · S Hellwig, F Emde, et al. · PubMed · 116

Analysis of single‐chain antibody production in Pichia pastoris using on‐line methanol control in fed‐batch and mixed‐feed fermentations

2001 · Stephan Hellwig, Frank Emde, et al. · Biotechnology and Bioengineering · 107

From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants

2015 · Markus Sack, Thomas Rademacher, et al. · Plant Biotechnology Journal · 97

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Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full‐size antibody in BY‐2 suspension culture

2010 · T. Holland, M. Sack, et al. · Biotechnology and Bioengineering · 93

Necessity of a Two-Stage Process for the Production of Azadirachtin-Related Limonoids in Suspension Cultures of Azadirachta indica

2003 · Keyur N. Raval, Stephan Hellwig, et al. · Journal of Bioscience and Bioengineering · 64

Towards molecular farming in the future: Pichia pastoris‐based production of single‐chain antibody fragments

1999 · Rainer Fischer, Jürgen Drossard, et al. · Biotechnology and Applied Biochemistry · 51

Towards industrial usefulness – cryo-cell-banking of transgenic BY-2 cell cultures

2006 · Kathrin Schmale, Thomas Rademacher, et al. · Journal of Biotechnology · 41

Increase of calnexin gene dosage boosts the secretion of heterologous proteins byHansenula polymorpha

2007 · Jens Klabunde, Sebastian Kleebank, et al. · FEMS Yeast Research · 36

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Improvement of a fermentation process for the production of two PfAMA1-DiCo-based malaria vaccine candidates in Pichia pastoris

2017 · Robin Kastilan, Alexander Boes, et al. · Scientific Reports · 27

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The in‐line measurement of plant cell biomass using radio frequency impedance spectroscopy as a component of process analytical technology

2013 · Tanja Holland, Daniel Blessing, et al. · Biotechnology Journal · 27

Production of carcinoembryonic antigen (CEA) N‐A3 domain in Pichia pastoris by fermentation

1999 · Stephan Hellwig, Frederic Robin, et al. · Biotechnology and Applied Biochemistry · 27

Polyclonal antibodies for specific detection of tobacco host cell proteins can be efficiently generated following RuBisCO depletion and the removal of endotoxins

2015 · Zulfaquar Ahmad Arfi, Stephan Hellwig, et al. · Biotechnology Journal · 24

Facing the Future with Pharmaceuticals from Plants

2007 · Rainer Fischer, Richard M. Twyman, et al. · Springer eBooks · 23

Comparative Fermentation

2004 · Stephan Hellwig, Christoph Stöckmann, et al. · 13

Production, Quality Control, Stability and Pharmacotoxicity of a Malaria Vaccine Comprising Three Highly Similar PfAMA1 Protein Molecules to Overcome Antigenic Variation

2016 · Bart W. Faber, Stephan Hellwig, et al. · PLoS ONE · 10

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Analysis of single‐chain antibody production in Pichia pastoris using on‐line methanol control in fed‐batch and mixed‐feed fermentations

2001 · Stephan Hellwig, Frank Emde, et al. · Biotechnology and Bioengineering · 4

Production of Antibodies in Hansenula polymorpha

2011 · Georg Melmer, Stephan Hellwig, et al. · Cell engineering · 3

Entwicklung von Fermentationsprozessen zur Produktion rekombinanter Antikörperfragmente in Pichia pastoris und Nicotiana tabacum

2000 · Stephan Hellwig, Fritz Kreuzaler · RWTH Publications (RWTH Aachen) · 2

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Bioreactor Production of scFv Fragments in Pichia pastoris

2010 · Stephan Hellwig, Georg Melmer · Springer eBooks · 1

Plant Cells

2004 · Rainer Fischer, Richard M Twyman, et al. · 1

Using plants as a production system for N-Glycosylated proteins of therapeutic relevance

2003 · Hellwig, S., Sack, M., et al. · Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft)

“Expression of Recombinant Antibodies in Plants and Cell Suspension Cultures”

1999 · Rainer Fischer, Jürgen Drossard, et al. · Current plant science and biotechnology in agriculture

Works count: 27

Citation count: 1,714

H-index: 16

I10-index: 18