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Hiroyasu Kokubo

Observed name: Hiroyasu KOKUBO
OpenAlex ID: A5004522006
Evaluation of Hypromellose Acetate Succinate (HPMCAS) as a Carrier in Solid Dispersions
2004 · Fumié Tanno, Yuichi Nishiyama, et al. · Drug Development and Industrial Pharmacy · 185
Dry coating: an innovative enteric coating method using a cellulose derivative
1999 · Sakae Obara, Naosuke Maruyama, et al. · European Journal of Pharmaceutics and Biopharmaceutics · 115
Study of Standard Tablet Formulation Based on Fluidized-Bed Granulation
1998 · Hisakazu Sunada, Masaki Hasegawa, et al. · Drug Development and Industrial Pharmacy · 23
Site‐Specific Drug Delivery to the Middle Region of the Small Intestine by Application of Enteric Coating with Hypromellose Acetate Succinate (HPMCAS)
2007 · Fumié K. Tanno, Shinji Sakuma, et al. · Journal of Pharmaceutical Sciences · 22
Development of Cellulose Derivatives as Novel Enteric Coating Agents Soluble at pH 3.5-4.5 and Higher.
1997 · Hiroyasu KOKUBO, Sakae OBARA, et al. · Chemical and Pharmaceutical Bulletin · 18
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Effect of Process Variables on the Properties and Binder Distribution of Granules Prepared by a High-Speed Mixer.
1996 · Hiroyasu KOKUBO, Hisakazu SUNADA · Chemical and Pharmaceutical Bulletin · 18
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Site-specific drug delivery to the middle-to-lower region of the small intestine reduces food–drug interactions that are responsible for low drug absorption in the fed state
2008 · Fumié K. Tanno, Shinji Sakuma, et al. · Journal of Pharmaceutical Sciences · 17
Critical Design Features of Phenyl Carboxylate-Containing Polymer Microbicides
2006 · Robert F. Rando, Sakae Obara, et al. · Antimicrobial Agents and Chemotherapy · 17
Effect of Several Cellulosic Binders on Particle Size Distribution in Fluidized Bed Granulation.
1995 · Hiroyasu KOKUBO, Shinichiro NAKAMURA, et al. · Chemical and Pharmaceutical Bulletin · 17
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Effect of Process Variables on the Properties and Binder Distribution of Granules Prepared in a Fluidized Bed.
1997 · Hiroyasu KOKUBO, Hisakazu SUNADA · Chemical and Pharmaceutical Bulletin · 14
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Effect of administration site in the gastrointestinal tract on bioavailability of poorly absorbed drugs taken after a meal
2006 · Shinji Sakuma, Fumié K. Tanno, et al. · Journal of Controlled Release · 12
Granulation of Acetaminophen by a Rotating Fluidized-Bed Granulator
2000 · Takeshi Kawaguchi, Hisakazu Sunada, et al. · Pharmaceutical Development and Technology · 12
Studies on single-dose toxicity of hydrophobically modified hydroxypropyl methylcellulose in rats.
1992 · Sakae OBARA, Hiroaki MUTO, et al. · The Journal of Toxicological Sciences · 12
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Application of Extremely Low Viscosity Methylcellulose (MC) for Pellet Film Coating.
1998 · Hiroyasu KOKUBO, Sakae OBARA, et al. · Chemical and Pharmaceutical Bulletin · 11
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Primary dermal and eye irritability tests of hydrophobically modified hydroxypropyl methylcellulose in rabbits.
1992 · Sakae OBARA, Hiroaki MUTO, et al. · The Journal of Toxicological Sciences · 11
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Effect of Several Cellulosic Binders on Particle Size Distribution of Granules Prepared by a High-Speed Mixer.
1993 · Hiroyasu KOKUBO, Shinichiro NAKAMURA, et al. · Chemical and Pharmaceutical Bulletin · 9
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Correlation between in vitro dissolution profiles from enteric-coated dosage forms and in vivo absorption in rats for high-solubility and high-permeability model drugs
2009 · Shinji Sakuma, Ryoko Ogura, et al. · Journal of Pharmaceutical Sciences · 7
Effect of Several Cellulosic Binders and Method of Their Addition on the Properties and Binder Distribution of Granules Prepared in an Agitating Fluidized Bed.
1998 · Hiroyasu KOKUBO, Chinatsu NAKASHIMA, et al. · Chemical and Pharmaceutical Bulletin · 4
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A novel oral dosage form that reduces food-drug interactions responsible for low drug absorption in the fed state: utilization of enteric coating agents that start to dissolve at higher pH
2010 · Fumié K Tanno, Shinji Sakuma, et al. · Drug Delivery System
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Study of the effect as a binder of cellulose derivatives on granulation.
1999 · Hiroyasu KOKUBO · Journal of the Society of Powder Technology Japan
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APPLICATIONS OF POLYMERIC MATERIALS FOR NOVEL PHARMACEUTICAL TECHNOLOGY / Novel Enteric Coating with Shin-Etsu AQOAT ( HPMCAS ) ~ DRY COATING ~
1996 · Naosuke Maruyama, Yuuichi Nishiyama, et al.
Various Grades of Low - Substituted Hydroxypropyl Cellulose and Their Properties
1991 · Hiroyasu Kokubo
The Application of Pharmacoat to Granulation in a Fluidizing Column
1990 · Sakaé Obara, Hiroaki MUTO, et al. · Journal of Pharmaceutical Investigation
Works count: 23
Citation count: 524
H-index: 12
I10-index: 15
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