Author

Shu-Chen Lu

Observed name: S.-y. Lu

Institution: Amgen (United States)

Observed institutions: Amgen (United States), Chinese Academy of Medical Sciences & Peking Union Medical College, Chang Gung Memorial Hospital

ORCID: 0009-0003-7113-3185

Observed ORCID: 0009-0003-7113-3185

OpenAlex ID: A5005215545

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects

2009 · Jing Xu, Shanaka Stanislaus, et al. · American Journal of Physiology-Endocrinology and Metabolism · 339

A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings

2024 · Murielle M. Véniant, Shu-Chen Lu, et al. · Nature Metabolism · 215

Glucose-Dependent Insulinotropic Polypeptide Receptor Therapies For The Treatment Of Obesity, Do Agonists = Antagonists?

2019 · Elizabeth A Killion, Shu-Chen Lu, et al. · Endocrine Reviews · 92

GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

2021 · Shu-Chen Lu, Michelle Chen, et al. · Cell Reports Medicine · 91

An Acyl-Ghrelin-Specific Neutralizing Antibody Inhibits the Acute Ghrelin-Mediated Orexigenic Effects in Mice

2009 · Shu-Chen Lu, Jing Xu, et al. · Molecular Pharmacology · 57

Value of surveillance computed tomography in the follow-up of diffuse large B-cell and follicular lymphomas

2012 · Tung-Liang Lin, Ming-Chung Kuo, et al. · Annals of Hematology · 35

GIPR-Ab/GLP-1 peptide–antibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice

2025 · Clarissa M. Liu, Elizabeth A. Killion, et al. · Nature Metabolism · 34

An apoA-I mimetic peptibody generates HDL-like particles and increases alpha-1 HDL subfraction in mice

2012 · Shu-Chen Lu, Larissa Atangan, et al. · Journal of Lipid Research · 17

Relevance and Clinical Significance of Serum Resistin Level in Obese T2DM Rhesus Monkey Models

2015 · S.-d. Qi, Z.-l. He, et al. · Experimental and Clinical Endocrinology & Diabetes · 9

Strategy for the Identification of GPR23/LPA 4 Receptor Agonists and Inverse Agonists

2010 · Soo Hang Wong, Rommel Mallari, et al. · Assay and Drug Development Technologies · 5

Discovery of AMG 133, a Glucose-Dependent Insulinotropic Polypeptide Receptor Antagonist and Glucagon-Like Peptide 1 Receptor Agonist Antibody-Drug Conjugate for the Treatment of Obesity

2026 · Bin Wu, James R. Falsey, et al. · Journal of Medicinal Chemistry · 3

Works count: 11

Citation count: 896

H-index: 9

I10-index: 8