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Guoxun Zheng
Observed names:
Guo-Xun Zheng,
Guo-xun Zheng
Institution:
Viva Biotech (China)
Observed institutions:
Chongqing University,
ShanghaiTech University,
Viva Biotech (China),
Zhejiang University,
Xi'an Jiaotong University
ORCID:
0000-0003-1388-6528
Observed ORCID:
0000-0003-1388-6528
OpenAlex ID:
A5005286554
What Contributes to Serotonin–Norepinephrine Reuptake Inhibitors’ Dual-Targeting Mechanism? The Key Role of Transmembrane Domain 6 in Human Serotonin and Norepinephrine Transporters Revealed by Molecular Dynamics Simulation
2018
·
Weiwei Xue
, Fengyuan Yang
, et al.
·
ACS Chemical Neuroscience
·
288
Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder
2018
·
Weiwei Xue
, Panpan Wang
, et al.
·
Physical Chemistry Chemical Physics
·
150
Exploring the Binding Mechanism of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators in Clinical Trials by Molecular Dynamics Simulations
2018
·
Tingting Fu
, Guoxun Zheng
, et al.
·
ACS Chemical Neuroscience
·
115
Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD
2017
·
Panpan Wang
, Tingting Fu
, et al.
·
Biochimica et Biophysica Acta (BBA) - General Subjects
·
56
Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study
2016
·
Guoxun Zheng
, Weiwei Xue
, et al.
·
Scientific Reports
·
51
PDF
The binding mode of vilazodone in the human serotonin transporter elucidated by ligand docking and molecular dynamics simulations
2020
·
Yang Zhang
, Guoxun Zheng
, et al.
·
Physical Chemistry Chemical Physics
·
47
Computational characterization of the selective inhibition of human norepinephrine and serotonin transporters by an escitalopram scaffold
2018
·
Guoxun Zheng
, Fengyuan Yang
, et al.
·
Physical Chemistry Chemical Physics
·
39
Revealing vilazodone's binding mechanism underlying its partial agonism to the 5-HT 1A receptor in the treatment of major depressive disorder
2017
·
Guoxun Zheng
, Weiwei Xue
, et al.
·
Physical Chemistry Chemical Physics
·
39
Subtype-selective mechanisms of negative allosteric modulators binding to group I metabotropic glutamate receptors
2020
·
Ting-ting Fu
, Gao Tu
, et al.
·
Acta Pharmacologica Sinica
·
36
PDF
Recent Advances and Challenges of the Drugs Acting on Monoamine Transporters
2018
·
Weiwei Xue
, Tingting Fu
, et al.
·
Current Medicinal Chemistry
·
32
Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/β-catenin signaling in obstructed kidneys in vivo
2022
·
Yu Zhang
, Yang Wang
, et al.
·
Journal of Biological Chemistry
·
27
PDF
Prediction of the binding mode and resistance profile for a dual-target pyrrolyl diketo acid scaffold against HIV-1 integrase and reverse-transcriptase-associated ribonuclease H
2018
·
Fengyuan Yang
, Guoxun Zheng
, et al.
·
Physical Chemistry Chemical Physics
·
27
Computational Chemistry in Structure-Based Solute Carrier Transporter Drug Design: Recent Advances and Future Perspectives
2024
·
Gao Tu
, Tingting Fu
, et al.
·
Journal of Chemical Information and Modeling
·
20
Comparison of computational model and X-ray crystal structure of human serotonin transporter: potential application for the pharmacology of human monoamine transporters
2017
·
Fengyuan Yang
, Tingting Fu
, et al.
·
Molecular Simulation
·
20
Discovery of novel 3-benzylquinazolin-4(3H)-ones as potent vasodilative agents
2014
·
Sai-Jie Zuo
, Sen Li
, et al.
·
Bioorganic & Medicinal Chemistry Letters
·
20
Rational Remodeling of Atypical Scaffolds for the Design of Photoswitchable Cannabinoid Receptor Tools
2021
·
Tao Hu
, Guoxun Zheng
, et al.
·
Journal of Medicinal Chemistry
·
18
Targeting PI4KA sensitizes refractory leukemia to chemotherapy by modulating the ERK/AMPK/OXPHOS axis
2022
·
Xiuxing Jiang
, Xiangtao Huang
, et al.
·
Theranostics
·
15
Selective Inhibition of HDAC1 by Macrocyclic Polypeptide for the Treatment of Glioblastoma: A Binding Mechanistic Analysis Based on Molecular Dynamics
2020
·
Yang Zhang
, Tingting Fu
, et al.
·
Frontiers in Molecular Biosciences
·
11
PDF
Synthesis and Vasodilatation of Homoisoflavones
2015
·
Guoxun Zheng
, Zongchang Zhang
, et al.
·
Chinese Journal of Organic Chemistry
·
4
PDF
Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD General subjects
2017
·
Panpan Wang
, Tingting Fu
, et al.
·
Biochimica et Biophysica Acta
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Works count:
20
Citation count:
1,015
H-index:
16
I10-index:
18
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