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Anna Kruschinski
Observed names:
A Kruschinski,
A. Kruschinski,
Kruschinski, Anna
Observed institutions:
Max Delbrück Center,
Stanford Medicine,
Noxxon Pharma (Germany),
Stanford University
OpenAlex ID:
A5005313731
The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
2013
·
Julia Hoellenriegel
, Dirk Zboralski
, et al.
·
Blood
·
244
Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas
2008
·
Anna Kruschinski
, Andreas Moosmann
, et al.
·
Proceedings of the National Academy of Sciences
·
197
SDF-1 Inhibition Targets the Bone Marrow Niche for Cancer Therapy
2014
·
Aldo M. Roccaro
, Antonio Sacco
, et al.
·
Cell Reports
·
136
PDF
Blockade of SDF-1 after irradiation inhibits tumor recurrences of autochthonous brain tumors in rats
2013
·
Shie-Chau Liu
, Reem Alomran
, et al.
·
Neuro-Oncology
·
95
PDF
Hematopoietic Stem and Progenitor Cell Mobilization in Mice and Humans by a First-in-Class Mirror-Image Oligonucleotide Inhibitor of CXCL12
2013
·
A Vater
, J Sahlmann
, et al.
·
Clinical Pharmacology & Therapeutics
·
84
PDF
Efficacy of CAR T-cell Therapy in Large Tumors Relies upon Stromal Targeting by IFNγ
2014
·
Ana Textor
, Joanna J. Listopad
, et al.
·
Cancer Research
·
82
PDF
Olaptesed pegol, an anti-CXCL12/SDF-1 Spiegelmer, alone and with bortezomib–dexamethasone in relapsed/refractory multiple myeloma: a Phase IIa Study
2017
·
H Ludwig
, K Weisel
, et al.
·
Leukemia
·
80
PDF
Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition
2017
·
Ellen L. Weisberg
, Martin Sattler
, et al.
·
Oncotarget
·
25
PDF
CXCL12/SDF-1-Dependent Retinal Migration of Endogenous Bone Marrow-Derived Stem Cells Improves Visual Function after Pharmacologically Induced Retinal Degeneration
2016
·
Volker Enzmann
, Stéphanie Lecaudé
, et al.
·
Stem Cell Reviews and Reports
·
25
CXCL12-induced VLA-4 activation is impaired in trisomy 12 chronic lymphocytic leukemia cells: a role for CCL21
2015
·
Sylvia Ganghammer
, Evelyn Hutterer
, et al.
·
Oncotarget
·
21
PDF
Effects of CCL2/CCR2 Blockade in Acute Myeloid Leukemia
2015
·
Rodrigo Omar Jacamo
, Hong Mu
, et al.
·
Blood
·
17
Results from a Phase IIa Study of the Anti-CXCL12 Spiegelmer Olaptesed Pegol (NOX-A12) in Combination with Bendamustine/Rituximab in Patients with Chronic Lymphocytic Leukemia
2014
·
Michael Steurer
, Marco Montillo
, et al.
·
Blood
·
12
Final Results from the Phase IIa Study of the Anti-CXCL12 Spiegelmer® Olaptesed Pegol (NOX-A12) in Combination with Bortezomib and Dexamethasone in Patients with Multiple Myeloma
2014
·
Heinz Ludwig
, Katja Weisel
, et al.
·
Blood
·
10
Anti-CXCL12/SDF-1 Spiegelmer® Nox-A12 Alone and In Combination With Bendamustine and Rituximab In Patients With Relapsed Chronic Lymphocytic Leukemia (CLL): Results From A Phase IIa Study
2013
·
Marco Gobbi
, Michael Steurer
, et al.
·
Blood
·
10
Anti-CXCL12/SDF-1 Spiegelmer® Nox-A12 Alone and In Combination With Bortezomib and Dexamethasone In Patients With Relapsed Multiple Myeloma: Results From A Phase IIa Study
2013
·
Heinz Ludwig
, Katja Weisel
, et al.
·
Blood
·
9
SDF-1 Inhibition Using Spiegelmer® Nox-A12 As a Novel Strategy For Targeting AML Cells Within Their BM Microenvironment
2013
·
Rodrigo Jacamo
, Zhihong Zeng
, et al.
·
Blood
·
4
CXCL12 Inhibition By Nox-A12 (Olaptesed Pegol) Synergizes with the ADCC Activity of CD20 Antibodies By Increasing NK Cell Infiltration in a 3D Lymphoma Model
2016
·
Dirk Zboralski
, Anna Kruschinski
, et al.
·
Blood
·
3
Mode of Action of the SDF-1/CXCL12 Inhibiting Spiegelmer® Nox-A12 and Its Impact On Chronic Lymphocytic Leukemia (CLL) Cell Motility and Chemosensitization
2012
·
Dirk Zboralski
, Julia Hoellenriegel
, et al.
·
Blood
·
3
Phase IIa Study of the Anti-CXCL12/SDF-1 Spiegelmer® Nox-A12 Alone and Combined with Bendamustine/Rituximab in Patients with Relapsed Chronic Lymphocytic Leukemia (CLL)
2012
·
Marco Gobbi
, Federico Caligaris-Cappio
, et al.
·
Blood
·
3
In Vivo Targeting of Stromal-Derived Factor-1 As a Strategy to Prevent Myeloma Cell Dissemination to Distant Bone Marrow Niches
2012
·
Aldo M. Roccaro
, Antonio Sacco
, et al.
·
Blood
·
3
The Spiegelmer Nox-A12, a Novel SDF-1 (CXCL12) Inhibitor, and Its Effects on Chronic Lymphocytic Leukemia (CLL) Cell Migration,
2011
·
Julia Hoellenriegel
, Dirk Zboralski
, et al.
·
Blood
·
3
CXCL12 inhibition with NOX-A12 (olaptesed pegol) increases T and NK cell infiltration and synergizes with immune checkpoint blockade in tumour-stroma spheroids
2016
·
D. Zboralski
, A. Kruschinski
, et al.
·
Annals of Oncology
·
2
Interim Results From a Phase Iia Study of the Anti-cxcl12 Spiegelmer Olaptesed Pegol (nox-a12) in Combination With Bendamustine/rituximab in Patients With Chronic Lymphocytic Leukemia
2014
·
Michael Steurer
, Lydia Scarfò
, et al.
·
Haematologica
·
2
The Spiegelmer® Nox-A12 Abrogates Homing Of Human CLL Cells To Bone Marrow and Mobilizes Murine CLL Cells In The Eμ-TCL1 Transgenic Mouse Model Of CLL
2013
·
Elisabeth Hinterseer
, Tamara Girbl
, et al.
·
Blood
·
2
Abstract PR14: In vivo targeting of stromal-derived factor-1 as a strategy to prevent myeloma cell dissemination to distant bone marrow niches
2015
·
Aldo M. Roccaro
, Antonio Sacco
, et al.
·
Cancer Research
·
1
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Works count:
45
Citation count:
1,080
H-index:
12
I10-index:
14
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