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Rosemary O’Connor

Observed names: R O'Connor, R O-Connor, R. O'Connor, R. O’Connor, R.  O'Connor, ROSEMARY O'CONNOR, Rosemary O'Connor, Rosemary OConnor
ORCID: 0000-0002-0687-3422
Observed ORCID: 0000-0002-0687-3422
OpenAlex ID: A5005360775
Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling
2008 · Aileen M. Moloney, Rebecca J. Griffin, et al. · Neurobiology of Aging · 774
Induction of apoptosis by the Bcl-2 homologue Bak
1995 · Thomas Chittenden, Elizabeth A. Harrington, et al. · Nature · 741
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
2005 · Rebecca J. Griffin, Aileen Moloney, et al. · Journal of Neurochemistry · 468
Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer
2013 · Suzanne A Eccles, Eric O Aboagye, et al. · Breast Cancer Research · 424
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Identification of Domains of the Insulin-Like Growth Factor I Receptor That Are Required for Protection from Apoptosis
1997 · Rosemary O’Connor, Andrea Kauffmann-Zeh, et al. · Molecular and Cellular Biology · 253
PBK/TOPK promotes tumour cell proliferation through p38 MAPK activity and regulation of the DNA damage response
2006 · V Ayllón, R O'Connor · Oncogene · 153
RACK1 Is an Insulin-like Growth Factor 1 (IGF-1) Receptor-interacting Protein That Can Regulate IGF-1-mediated Akt Activation and Protection from Cell Death
2002 · Patrick A. Kiely, Anagha Sant, et al. · Journal of Biological Chemistry · 150
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The Insulin-like Growth Factor-I–mTOR Signaling Pathway Induces the Mitochondrial Pyrimidine Nucleotide Carrier to Promote Cell Growth
2007 · Suzanne Floyd, Cedric Favre, et al. · Molecular Biology of the Cell · 128
Insulin-like growth factor 1 signaling is essential for mitochondrial biogenesis and mitophagy in cancer cells
2017 · Amy Lyons, Michael Coleman, et al. · Journal of Biological Chemistry · 115
Regulation of Insulin-Like Growth Factor Type I (IGF-I) Receptor Kinase Activity by Protein Tyrosine Phosphatase 1B (PTP-1B) and Enhanced IGF-I-Mediated Suppression of Apoptosis and Motility in PTP-1B-Deficient Fibroblasts
2002 · Deirdre A. Buckley, Alan Cheng, et al. · Molecular and Cellular Biology · 115
Mystique Is a New Insulin-like Growth Factor-I-regulated PDZ-LIM Domain Protein That Promotes Cell Attachment and Migration and Suppresses Anchorage-independent Growth
2005 · Gary Loughran, Nollaig C. Healy, et al. · Molecular Biology of the Cell · 114
Insulin-Like Growth Factor I Controls a Mutually Exclusive Association of RACK1 with Protein Phosphatase 2A and β1 Integrin To Promote Cell Migration
2006 · Patrick A. Kiely, Denise O'Gorman, et al. · Molecular and Cellular Biology · 110
Identification of an acetylation-dependant Ku70/FLIP complex that regulates FLIP expression and HDAC inhibitor-induced apoptosis
2012 · E Kerr, C Holohan, et al. · Cell Death and Differentiation · 109
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Phosphorylation of RACK1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase
2009 · Patrick A. Kiely, George S. Baillie, et al. · Journal of Biological Chemistry · 103
Metastatic susceptibility locus, an 8p hot-spot for tumour progression disrupted in colorectal liver metastases: 13 candidate genes examined at the DNA, mRNA and protein level
2008 · Donia P Macartney-Coxson, Kylie A Hood, et al. · BMC Cancer · 103
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A Cell Viability Assay Based on Monitoring Respiration by Optical Oxygen Sensing
2000 · Tomás C. O'Riordan, Deirdre Buckley, et al. · Analytical Biochemistry · 99
Fluorescence-Based Cell Viability Screening Assays Using Water-Soluble Oxygen Probes
2003 · James Hynes, Suzanne Floyd, et al. · SLAS DISCOVERY · 96
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IGF-1 Signalling Regulates Mitochondria Dynamics and Turnover through a Conserved GSK-3β–Nrf2–BNIP3 Pathway
2020 · Sarah Riis, Joss B. Murray, et al. · Cells · 88
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Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells
2010 · C Favre, A Zhdanov, et al. · Oncogene · 85
RACK1-mediated Integration of Adhesion and Insulin-like Growth Factor I (IGF-I) Signaling and Cell Migration Are Defective in Cells Expressing an IGF-I Receptor Mutated at Tyrosines 1250 and 1251
2004 · Patrick A. Kiely, Madeline Leahy, et al. · Journal of Biological Chemistry · 85
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Regulation of IGF-I Receptor Signaling in Tumor Cells
2003 · R.  O'Connor · Hormone and Metabolic Research · 82
Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and β1 Integrin and for Tumor Cell Proliferation and Migration
2008 · Patrick A. Kiely, George S. Baillie, et al. · Journal of Biological Chemistry · 75
Eukaryotic membrane protein overproduction in Lactococcus lactis
2005 · Edmund RS Kunji, Ka Wai Chan, et al. · Current Opinion in Biotechnology · 71
Heme-binding Protein HRG-1 Is Induced by Insulin-like Growth Factor I and Associates with the Vacuolar H+-ATPase to Control Endosomal pH and Receptor Trafficking
2009 · Katie M. O'Callaghan, Veronica Ayllon, et al. · Journal of Biological Chemistry · 70
Insulin‐like growth factor‐1 activates Akt and Jun N‐terminal kinases (JNKs) in promoting the survival of T lymphocytes
2002 · Patrick T. Walsh, Loraine M. Smith, et al. · Immunology · 69
Works count: 138
Citation count: 6,514
H-index: 42
I10-index: 75
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