Author

Maria Carlsen Melander

Observed names: M.C. Melander, MARIA C. MELANDER, Maria C Melander, Maria C. Melander, Maria Carlsén Melander, Maria Melander

Institution: Symphogen (Denmark)

Observed institutions: University of Copenhagen, Copenhagen University Hospital, Rigshospitalet, Symphogen (Denmark)

ORCID: 0009-0002-6985-1826

Observed ORCID: 0009-0002-6985-1826

OpenAlex ID: A5005390565

The Non-phagocytic Route of Collagen Uptake

2011 · Daniel H. Madsen, Signe Ingvarsen, et al. · Journal of Biological Chemistry · 121

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CD4+ and CD8a+ PET imaging predicts response to novel PD-1 checkpoint inhibitor: studies of Sym021 in syngeneic mouse cancer models

2019 · Lotte K. Kristensen, Camilla Fröhlich, et al. · Theranostics · 98

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A Novel Functional Role of Collagen Glycosylation

2011 · Henrik J. Jürgensen, Daniel H. Madsen, et al. · Journal of Biological Chemistry · 91

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The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review)

2015 · MARIA C. MELANDER, HENRIK J. JÜRGENSEN, et al. · International Journal of Oncology · 83

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Targeting a Single Function of the Multifunctional Matrix Metalloprotease MT1-MMP

2013 · Signe Ingvarsen, Astrid Porse, et al. · Journal of Biological Chemistry · 60

Complex Determinants in Specific Members of the Mannose Receptor Family Govern Collagen Endocytosis

2014 · Henrik J. Jürgensen, Kristina Johansson, et al. · Journal of Biological Chemistry · 55

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Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis

2012 · Daniel H Madsen, Henrik J Jürgensen, et al. · The Journal of Pathology · 54

The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

2017 · Christoffer Fagernæs Nielsen, Sander Maarten van Putten, et al. · Oncotarget · 40

Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180

2015 · Lars H Engelholm, Maria C Melander, et al. · The Journal of Pathology · 37

Sym021, a promising anti-PD1 clinical candidate antibody derived from a new chicken antibody discovery platform

2019 · Torben Gjetting, Monika Gad, et al. · mAbs · 34

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Differential Actions of the Endocytic Collagen Receptor uPARAP/Endo180 and the Collagenase MMP-2 in Bone Homeostasis

2013 · Daniel H. Madsen, Henrik J. Jürgensen, et al. · PLoS ONE · 32

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Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

2020 · Signe Z. Ingvarsen, Henrik Gårdsvoll, et al. · Scientific Reports · 24

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A phase I study of Sym021, an anti-PD-1 antibody (Ab), alone and in combination with Sym022 (anti-LAG-3) or Sym023 (anti-TIM-3)

2019 · A. Spreafico, F. Janku, et al. · Annals of Oncology · 16

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MMP9 is protective against lethal inflammatory mass lesions in the mouse colon

2010 · Andreas Hald, Birgitte Rønø, et al. · Disease Models & Mechanisms · 15

Abstract 5626: Preclinical characterization of Sym022, a novel anti-LAG3 antibody

2018 · Michael M. Grandal, Maria C. Melander, et al. · Cancer Research · 8

Sym004-induced EGFR elimination is associated with profound anti-tumor activity in EGFRvIII patient-derived glioblastoma models

2018 · Stephen T. Keir, Vidyalakshmi Chandramohan, et al. · Journal of Neuro-Oncology · 8

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Abstract LB220: S095029: a novel clinical-stage Fc-silenced NKG2A-blocking antibody with best-in-class potential

2023 · Maria Melander, Bruno Laugel · Cancer Research · 4

Abstract 1797: Preclinical characterization of Sym024, a novel anti-CD73 antibody

2021 · Janus S. Jakobsen, Matteo Riva, et al. · Cancer Research · 3

Sym024 Interacts with a Unique Epitope on the CD73 Homodimer, Favoring Effective Bivalent Binding to Improve Anti–PD-1 Therapy

2026 · Janus S. Jakobsen, Michael M. Grandal, et al. · Clinical Cancer Research · 2

Preclinical characterization of S095029, a novel clinical-stage Fc-attenuated NKG2A-blocking antibody for cancer immunotherapy

2026 · Maria Carlsen Melander, Franziska Uhlenbrock, et al. · Frontiers in Oncology

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Supplementary Table S6 from Sym024 Interacts with a Unique Epitope on the CD73 Homodimer, Favoring Effective Bivalent Binding to Improve Anti–PD-1 Therapy