Author

Peter W. Kenny

Observed names: Kenny, Peter, Kenny, Peter W, P. W. KENNY, P. W. Kenny, Peter Kenny, Peter W Kenny

Observed institutions: AstraZeneca (United Kingdom), Commonwealth Scientific and Industrial Research Organisation, University of Minnesota, Universidade de São Paulo, Radboud University Medical Center, University of Oxford, Radboud Institute for Molecular Life Sciences, Instituto de Química de São Carlos, University of Sheffield

ORCID: 0000-0002-3105-2909

Observed ORCID: 0000-0002-3105-2909

OpenAlex ID: A5005482561

Matched Molecular Pairs as a Guide in the Optimization of Pharmaceutical Properties; a Study of Aqueous Solubility, Plasma Protein Binding and Oral Exposure

2006 · Andrew G. Leach, Huw D. Jones, et al. · Journal of Medicinal Chemistry · 288

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

2021 · Jitske Jansen, Katharina C. Reimer, et al. · Cell stem cell · 276

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Hydrogen-Bond Donors in Drug Design

2022 · Peter W. Kenny · Journal of Medicinal Chemistry · 270

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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

2023 · Melissa L. Boby, Daren Fearon, et al. · Science · 252

Structure Modification in Chemical Databases

2005 · Peter W. Kenny, Jens Sadowski · Methods and principles in medicinal chemistry · 174

Hydrogen Bonding, Electrostatic Potential, and Molecular Design

2009 · Peter W. Kenny · Journal of Chemical Information and Modeling · 168

An Integrated Approach to Fragment-Based Lead Generation:Philosophy, Strategy and Case Studies from AstraZenecas Drug Discovery Programmes

2007 · Jeffrey Albert, Niklas Blomberg, et al. · Current Topics in Medicinal Chemistry · 126

The nature of ligand efficiency

2019 · Peter W. Kenny · Journal of Cheminformatics · 114

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Identification of Compounds with Nanomolar Binding Affinity for Checkpoint Kinase-1 Using Knowledge-Based Virtual Screening

2004 · Paul D. Lyne, Peter W. Kenny, et al. · Journal of Medicinal Chemistry · 113

Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors

2015 · Leandro A. A. Avelar, Cristian D. Camilo, et al. · PLoS neglected tropical diseases · 91

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Pharmacophoric pattern matching in files of three-dimensional chemical structures: Comparison of conformational-searching algorithms for flexible searching

1994 · David E. Clark, Gareth Jones, et al. · Journal of Chemical Information and Computer Sciences · 91

Inflation of correlation in the pursuit of drug-likeness

2013 · Peter W. Kenny, Carlos A. Montanari · Journal of Computer-Aided Molecular Design · 81

Structure-based design of protein tyrosine phosphatase-1B inhibitors

2005 · Emma Black, Jason Breed, et al. · Bioorganic & Medicinal Chemistry Letters · 81

Design of compound libraries for fragment screening

2009 · Niklas Blomberg, David A. Cosgrove, et al. · Journal of Computer-Aided Molecular Design · 77

Prediction of hydrogen bond basicity from computed molecular electrostatic properties: implications for comparative molecular field analysis

1994 · Peter W. Kenny · Journal of the Chemical Society Perkin Transactions 2 · 71

New nonpeptide angiotensin II receptor antagonists. 3. Synthesis, biological properties, and structure-activity relationships of 2-alkyl-4-(biphenylylmethoxy)pyridine derivatives

1993 · Robert H. Bradbury, Christopher P. Allott, et al. · Journal of Medicinal Chemistry · 71

Dipeptidyl nitrile inhibitors of Cathepsin L

2009 · Nabil Asaad, Paul A. Bethel, et al. · Bioorganic & Medicinal Chemistry Letters · 69

Hydrogen Bond Basicity Prediction for Medicinal Chemistry Design

2016 · Peter W. Kenny, Carlos A. Montanari, et al. · Journal of Medicinal Chemistry · 66

Ligand efficiency metrics considered harmful

2014 · Peter W. Kenny, Andrei Leitão, et al. · Journal of Computer-Aided Molecular Design · 63

Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors

2017 · Antonio C. B. Burtoloso, Sérgio de Albuquerque, et al. · PLoS neglected tropical diseases · 59

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A comparative study of warheads for design of cysteine protease inhibitors

2017 · Daniel G. Silva, Jean F.R. Ribeiro, et al. · Bioorganic & Medicinal Chemistry Letters · 54

Toward Prediction of Alkane/Water Partition Coefficients

2008 · Anita Toulmin, J. Matthew Wood, et al. · Journal of Medicinal Chemistry · 53

Pharmacophoric pattern matching in files of three-dimensional chemical structures: use of bounded distance matrices for the representation and searching of conformationally flexible molecules

1992 · David E. Clark, Peter Willett, et al. · Journal of Molecular Graphics · 50

Discovery of novel imidazo[1,2-a]pyridines as inhibitors of the insulin-like growth factor-1 receptor tyrosine kinase

2011 · Richard Ducray, Iain Simpson, et al. · Bioorganic & Medicinal Chemistry Letters · 48

Comment on The Ecstasy and Agony of Assay Interference Compounds

2017 · Peter W. Kenny · Journal of Chemical Information and Modeling · 43

Works count: 84

Citation count: 3,569

H-index: 31

I10-index: 51