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Maxime Le Merdy

Observed names: Maxime LeMerdy, Maxime Le Merdy
Observed institutions: United States Food and Drug Administration, Center for Drug Evaluation and Research, Hôpital Cochin, Assistance Publique – Hôpitaux de Paris, Université Paris Descartes, Simulations Plus (United States)
ORCID: 0000-0003-2629-8039
Observed ORCID: 0000-0003-2629-8039
OpenAlex ID: A5005739323
Application of Mechanistic Ocular Absorption Modeling and Simulation to Understand the Impact of Formulation Properties on Ophthalmic Bioavailability in Rabbits: a Case Study Using Dexamethasone Suspension
2019 · Maxime Le Merdy, Jianghong Fan, et al. · The AAPS Journal · 42
PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Kidney in Pregnant Subjects and Fetus
2021 · Ke Xu Szeto, Maxime Le Merdy, et al. · The AAPS Journal · 31
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Physiologically Based Pharmacokinetic Model to Support Ophthalmic Suspension Product Development
2020 · Maxime Le Merdy, Ming-Liang Tan, et al. · The AAPS Journal · 31
Ocular Physiologically Based Pharmacokinetic Modeling for Ointment Formulations
2020 · Maxime Le Merdy, Jessica Spires, et al. · Pharmaceutical Research · 25
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Developing Clinically Relevant Dissolution Specifications (CRDSs) for Oral Drug Products: Virtual Webinar Series
2022 · Mark McAllister, Talia Flanagan, et al. · Pharmaceutics · 19
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Predicting Human Dermal Drug Concentrations Using PBPK Modeling and Simulation: Clobetasol Propionate Case Study
2024 · William W. van Osdol, Jasmina Novakovic, et al. · AAPS PharmSciTech · 18
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Protocol for evaluation of topical ophthalmic drug products in different compartments of fresh eye tissues in a rabbit model
2018 · Ashok Chockalingam, Lin Xu, et al. · Journal of Pharmacological and Toxicological Methods · 17
Clinical Ocular Exposure Extrapolation for Ophthalmic Solutions Using PBPK Modeling and Simulation
2022 · Maxime Le Merdy, Farah AlQaraghuli, et al. · Pharmaceutical Research · 16
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Development of PBPK model for intra-articular injection in human: methotrexate solution and rheumatoid arthritis case study
2021 · Maxime Le Merdy, Jim Mullin, et al. · Journal of Pharmacokinetics and Pharmacodynamics · 15
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Development of Mechanistic In Vitro–In Vivo Extrapolation to Support Bioequivalence Assessment of Long-Acting Injectables
2024 · Daniela Amaral Silva, Maxime Le Merdy, et al. · Pharmaceutics · 14
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Clinical Ocular Exposure Extrapolation for a Complex Ophthalmic Suspension Using Physiologically Based Pharmacokinetic Modeling and Simulation
2024 · Maxime Le Merdy, Jessica Spires, et al. · Pharmaceutics · 13
PBPK Modeling Approach to Predict the Behavior of Drugs Cleared by Metabolism in Pregnant Subjects and Fetuses
2024 · Maxime Le Merdy, Ke Xu Szeto, et al. · Pharmaceutics · 11
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Physiologically Based Pharmacokinetic Modeling Approach to Identify the Drug–Drug Interaction Mechanism of Nifedipine and a Proton Pump Inhibitor, Omeprazole
2020 · Maxime Le Merdy, Ming-Liang Tan, et al. · European Journal of Drug Metabolism and Pharmacokinetics · 10
Mechanistic Modeling of Intramuscular Administration of a Long-acting Injectable Accounting for Tissue Response At the Depot Site
2025 · Daniela A. Silva, Maxime Le Merdy, et al. · The AAPS Journal · 8
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Use of the Same Model or Modeling Strategy Across Multiple Submissions: Focus on Complex Drug Products
2024 · Ross L. Walenga, Andrew H. Babiskin, et al. · The AAPS Journal · 8
Principales modifications pharmacocinétiques chez l’enfant
2014 · Simon Buatois, Maxime Le Merdy, et al. · Annales de Toxicologie Analytique · 7
Mechanistic modeling of ophthalmic, nasal, injectable, and implant generic drug products: A workshop summary report
2023 · Ming‐Liang Tan, Sajeev Chandran, et al. · CPT Pharmacometrics & Systems Pharmacology · 6
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Prediction of Monoclonal Antibody Pharmacokinetics in Pediatric Populations Using PBPK Modeling and Simulation
2025 · Chiara Zunino, Virginie Gualano, et al. · Pharmaceutics · 4
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In silico predictions of absorption of MDI substances after dermal or inhalation exposures to support a category based read-across assessment
2022 · Michael Bartels, William van Osdol, et al. · Regulatory Toxicology and Pharmacology · 4
Clinical Ocular Exposure Extrapolation for an Ophthalmic Ointment Using PBPK Modeling and Simulation
2025 · Maxime Le Merdy, Ming-Liang Tan, et al. · The AAPS Journal · 3
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Ethyl glucuronide dans les urines : étude de stabilité et données en toxicologie clinique
2014 · Maxime Le Merdy, Xavier Decleves, et al. · Annales de Toxicologie Analytique · 1
Physiologically-Based Absorption Models for Complex Formulations and Dosage Forms
2024 · Maxime Le Merdy, William W van Osdol, et al. · CRC Press eBooks
Correction to: Predicting Human Dermal Drug Concentrations Using PBPK Modeling and Simulation: Clobetasol Propionate Case Study
2024 · William W. van Osdol, Jasmina Novakovic, et al. · AAPS PharmSciTech
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Physiologically Based Pharmacokinetic Models for Infliximab, Ipilimumab, and Nivolumab Developed with GastroPlus® to Predict Hepatic Concentrations
2024 · Celeste Vallejo, Cameron Meaney, et al.
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Works count: 24
Citation count: 298
H-index: 11
I10-index: 12
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