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Alexander Birkmann

Observed names: A Birkmann, A. Birkmann, Birkmann, Alexander
Institution: AiCuris (Germany)
ORCID: 0000-0001-5670-4814
Observed ORCID: 0000-0001-5670-4814
OpenAlex ID: A5005777715
Nucleotide sequence and expression of the selenocysteine-containing polypeptide of formate dehydrogenase (formate-hydrogen-lyase-linked) from Escherichia coli.
1986 · F Zinoni, A Birkmann, et al. · Proceedings of the National Academy of Sciences · 485
Cotranslational insertion of selenocysteine into formate dehydrogenase from Escherichia coli directed by a UGA codon.
1987 · F Zinoni, A Birkmann, et al. · Proceedings of the National Academy of Sciences · 235
Cell Surface Heparan Sulfate Is a Receptor for Human Herpesvirus 8 and Interacts with Envelope Glycoprotein K8.1
2001 · Alexander Birkmann, Kerstin Mahr, et al. · Journal of Virology · 213
Helicase–Primase Inhibitor Pritelivir for HSV-2 Infection
2014 · Anna Wald, Lawrence Corey, et al. · New England Journal of Medicine · 180
The product of the SNF2/SWI2 paralogue INO80 of Saccharomyces cerevisiae required for efficient expression of various yeast structural genes is part of a high‐molecular‐weight protein complex
1999 · Ronald Ebbert, Alexander Birkmann, et al. · Molecular Microbiology · 169
The Immunogenic Glycoprotein gp35-37 of Human Herpesvirus 8 Is Encoded by Open Reading Frame K8.1
1998 · Marc-Steffen Raab, Jens-Christian Albrecht, et al. · Journal of Virology · 122
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HSV antivirals – current and future treatment options
2016 · Alexander Birkmann, Holger Zimmermann · Current Opinion in Virology · 116
Effect of Pritelivir Compared With Valacyclovir on Genital HSV-2 Shedding in Patients With Frequent Recurrences
2016 · Anna Wald, Burkhard Timmler, et al. · JAMA · 114
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Involvement of the ntrA gene product in the anaerobic metabolism of Escherichia coli
1987 · A. Birkmann, R. G. Sawers, et al. · Molecular and General Genetics MGG · 114
Factors affecting transcriptional regulation of the formate-hydrogen-lyase pathway of Escherichia coli
1987 · A. Birkmann, F. Zinoni, et al. · Archives of Microbiology · 101
Kaposi's Sarcoma-Associated Herpesvirus gH/gL: Glycoprotein Export and Interaction with Cellular Receptors
2008 · Alexander Hahn, Alexander Birkmann, et al. · Journal of Virology · 71
Characterization of a cis regulatory DNA element necessary for formate induction of the formate dehydrogenase gene (fdhF) of Escherichia coli
1989 · A. Birkmann, A. Bock · Molecular Microbiology · 61
Discovery, Chemistry, and Preclinical Development of Pritelivir, a Novel Treatment Option for Acyclovir-Resistant Herpes Simplex Virus Infections
2022 · Alexander Birkmann, Susanne Bonsmann, et al. · Journal of Medicinal Chemistry · 60
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Novel non-heteroarylpyrimidine (HAP) capsid assembly modifiers have a different mode of action from HAPs in vitro
2018 · Angelica Corcuera, Katharina Stolle, et al. · Antiviral Research · 54
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Overview on the management of herpes simplex virus infections: Current therapies and future directions
2025 · Alexander Birkmann, Rob Saunders · Antiviral Research · 41
Efficacy of pritelivir and acyclovir in the treatment of herpes simplex virus infections in a mouse model of herpes simplex encephalitis
2017 · Debra C. Quenelle, Alexander Birkmann, et al. · Antiviral Research · 39
Mathematical modeling of herpes simplex virus-2 suppression with pritelivir predicts trial outcomes
2016 · Joshua T. Schiffer, David A. Swan, et al. · Science Translational Medicine · 39
Mismatch primer-based PCR reveals that helicase-primase inhibitor resistance mutations pre-exist in herpes simplex virus type 1 clinical isolates and are not induced during incubation with the inhibitor
2010 · S. Sukla, S. Biswas, et al. · Journal of Antimicrobial Chemotherapy · 38
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Baseline sensitivity of HSV-1 and HSV-2 clinical isolates and defined acyclovir-resistant strains to the helicase–primase inhibitor pritelivir
2013 · Hugh J. Field, Meei-Li Huang, et al. · Antiviral Research · 37
Lead Development of Thiazolylsulfonamides with Carbonic Anhydrase Inhibitory Action
2017 · Fabrizio Carta, Alexander Birkmann, et al. · Journal of Medicinal Chemistry · 27
Mutations close to functional motif IV in HSV-1 UL5 helicase that confer resistance to HSV helicase–primase inhibitors, variously affect virus growth rate and pathogenicity
2008 · Subhajit Biswas, Laurence S. Tiley, et al. · Antiviral Research · 26
No Evidence of Pritelivir Resistance Among Herpes Simplex Virus Type 2 Isolates After 4 Weeks of Daily Therapy
2016 · Paul T. Edlefsen, Alexander Birkmann, et al. · The Journal of Infectious Diseases · 25
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Pharmacokinetics-Pharmacodynamics of the Helicase-Primase Inhibitor Pritelivir following Treatment of Wild-Type or Pritelivir-Resistant Virus Infection in a Murine Herpes Simplex Virus 1 Infection Model
2014 · Subhajit Biswas, Soumi Sukla, et al. · Antimicrobial Agents and Chemotherapy · 20
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First‐in‐Human, Single‐ and Multiple‐Ascending‐Dose, Food‐Effect, and Absolute Bioavailability Trials to Assess the Pharmacokinetics, Safety, and Tolerability of Pritelivir, a Nonnucleoside Helicase‐Primase Inhibitor Against Herpes Simplex Virus in Healthy Subjects
2023 · Dirk Kropeit, Susanne Bonsmann, et al. · Clinical Pharmacology in Drug Development · 18
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Effects of therapy using a helicase–primase inhibitor (HPI) in mice infected with deliberate mixtures of wild-type HSV-1 and an HPI-resistant UL5 mutant
2010 · Soumi Sukla, Subhajit Biswas, et al. · Antiviral Research · 17
Works count: 48
Citation count: 2,555
H-index: 22
I10-index: 32
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