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Tadahiro Shinozawa

Observed name: Tadahiro SHINOZAWA
Observed institutions: Cincinnati Children's Hospital Medical Center, Tohoku University, Takeda (United States), Japan Pharmaceutical Manufacturers Association, Takeda (Japan), University of Cincinnati
ORCID: 0000-0001-6402-3824
Observed ORCID: 0000-0001-6402-3824
OpenAlex ID: A5006017684
Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
2019 · Rie Ouchi, Shodai Togo, et al. · Cell Metabolism · 561
High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids
2020 · Tadahiro Shinozawa, Masaki Kimura, et al. · Gastroenterology · 399
Human Organoids for Predictive Toxicology Research and Drug Development
2021 · Toshikatsu Matsui, Tadahiro Shinozawa · Frontiers in Genetics · 118
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Polygenic architecture informs potential vulnerability to drug-induced liver injury
2020 · Masaru Koido, Eri Kawakami, et al. · Nature Medicine · 85
Recapitulation of Clinical Individual Susceptibility to Drug-Induced QT Prolongation in Healthy Subjects Using iPSC-Derived Cardiomyocytes
2017 · Tadahiro Shinozawa, Koki Nakamura, et al. · Stem Cell Reports · 62
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Identification of microRNA biomarker candidates in urine and plasma from rats with kidney or liver damage
2016 · Francis S. Wolenski, Pooja Shah, et al. · Journal of Applied Toxicology · 42
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Reverse engineering liver buds through self-driven condensation and organization towards medical application
2016 · Tadahiro Shinozawa, Hiroshi Y. Yoshikawa, et al. · Developmental Biology · 38
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CSAHi study-2: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes: Assessment of reference compounds and comparison with non-clinical studies and clinical information
2017 · Yumiko Nozaki, Yayoi Honda, et al. · Regulatory Toxicology and Pharmacology · 37
Derivation of rat embryonic stem cells and generation of protease-activated receptor-2 knockout rats
2011 · Satoshi Yamamoto, Mitsugu Nakata, et al. · Transgenic Research · 34
Determination of Optimal Conditions for Parthenogenetic Activation and Subsequent Development of Rat Oocytes In Vitro
2004 · Eiji MIZUTANI, Jin-Yi JIANG, et al. · Journal of Reproduction and Development · 27
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Blood Neurofilament Light Chain as a Potential Biomarker for Central and Peripheral Nervous Toxicity in Rats
2021 · Tomoya Sano, Yasushi Masuda, et al. · Toxicological Sciences · 25
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High-Throughput Screening to Evaluate Inhibition of Bile Acid Transporters Using Human Hepatocytes Isolated From Chimeric Mice
2019 · Hiroshi Kohara, Piyush Bajaj, et al. · Toxicological Sciences · 25
Determination of Appropriate Stage of Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes for Drug Screening and Pharmacological Evaluation In Vitro
2012 · Tadahiro Shinozawa, Kenichi Imahashi, et al. · SLAS DISCOVERY · 25
A Novel Purification Method of Murine Embryonic Stem Cell– and Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes by Simple Manual Dissociation
2012 · Tadahiro Shinozawa, Hatsue Furukawa, et al. · SLAS DISCOVERY · 18
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Differential effect of recipient cytoplasm for microtubule organization and preimplantation development in rat reconstituted embryos with two‐cell embryonic cell nuclear transfer
2004 · Tadahiro Shinozawa, Eiji Mizutani, et al. · Molecular Reproduction and Development · 16
Cell-based two-dimensional morphological assessment system to predict cancer drug-induced cardiotoxicity using human induced pluripotent stem cell-derived cardiomyocytes
2019 · Toshikatsu Matsui, Kazumasa Miyamoto, et al. · Toxicology and Applied Pharmacology · 15
TAK-994 mechanistic investigation into drug-induced liver injury
2025 · Tadahiro Shinozawa, Kazumasa Miyamoto, et al. · Toxicological Sciences · 14
Cell-based high-throughput screening for the evaluation of reactive metabolite formation potential
2021 · Kosuke Harada, Hiroshi Kohara, et al. · Toxicology in Vitro · 11
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Video-based assessment of drug-induced effects on contractile motion properties using human induced pluripotent stem cell-derived cardiomyocytes
2020 · Yoshiko Okai, Keiko Matsune, et al. · Journal of Pharmacological and Toxicological Methods · 10
Increased mesodermal and mesendodermal populations by BMP4 treatment facilitates human iPSC line differentiation into a cardiac lineage
2019 · Maya Kimura, Hatsue Furukawa, et al. · Journal of Stem Cells and Regenerative Medicine · 10
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Physiological platelet aggregation assay to mitigate drug-induced thrombocytopenia using a microphysiological system
2024 · Kosuke Harada, Wang Wenlong, et al. · Scientific Reports · 9
Triclocarban induces lipid droplet accumulation and oxidative stress responses by inhibiting mitochondrial fatty acid oxidation in HepaRG cells
2024 · Hitoshi Nakamura, Toshikatsu Matsui, et al. · Toxicology Letters · 9
The mechanism of thrombocytopenia caused by cholesterol-conjugated antisense oligonucleotides
2023 · Kosuke Harada, Hideki Furukawa, et al. · Toxicology in Vitro · 9
Gene Expression Profiling of Functional Murine Embryonic Stem Cell-Derived Cardiomyocytes and Comparison with Adult Heart: Profiling of Murine ESC-Derived Cardiomyocytes
2009 · Tadahiro Shinozawa, Akiko Tsuji, et al. · SLAS DISCOVERY · 8
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Spontaneous recovery from sunitinib-induced disruption of sarcomere in human iPSC-cardiomyocytes and possible involvement of the Hippo pathway
2021 · Toshikatsu Matsui, Tadahiro Shinozawa · BMC Pharmacology and Toxicology · 7
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Works count: 38
Citation count: 1,628
H-index: 15
I10-index: 20
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