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Atsushi Imakiire

Observed name: Imakiire, Atsushi
Observed institution: JCR Pharmaceuticals (Japan)
ORCID: 0000-0001-8171-0183
Observed ORCID: 0000-0001-8171-0183
OpenAlex ID: A5006140040
Enzyme replacement with transferrin receptor-targeted α-L-iduronidase rescues brain pathology in mucopolysaccharidosis I mice
2023 · Sachiho Kida, Yuri Koshimura, et al. · Molecular Therapy — Methods & Clinical Development · 24
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Nonclinical safety evaluation of pabinafusp alfa, an anti-human transferrin receptor antibody and iduronate-2-sulfatase fusion protein, for the treatment of neuronopathic mucopolysaccharidosis type II
2021 · Ryuji Yamamoto, Eiji Yoden, et al. · Molecular Genetics and Metabolism Reports · 23
Pathogenic Roles of Heparan Sulfate and Its Use as a Biomarker in Mucopolysaccharidoses
2022 · Kohtaro Minami, Hideto Morimoto, et al. · International Journal of Molecular Sciences · 19
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Dose-dependent effects of a brain-penetrating iduronate-2-sulfatase on neurobehavioral impairments in mucopolysaccharidosis II mice
2022 · Hideto Morimoto, Hiroki Morioka, et al. · Molecular Therapy — Methods & Clinical Development · 13
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Transferrin Receptor-Targeted Iduronate-2-sulfatase Penetrates the Blood-Retinal Barrier and Improves Retinopathy in Mucopolysaccharidosis II Mice
2023 · Atsushi Imakiire, Hideto Morimoto, et al. · Molecular Pharmaceutics · 8
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A novel approach to CNS dysfunction of Pompe disease with a fusion protein consisting of anti-transferrin receptor antibody and GAA enzyme
2020 · Satowa Tanaka, Aya Yoshioka, et al. · Molecular Genetics and Metabolism · 3
Translational applicability of human blood-brain barrier spheroid models for the development of brain-penetrant therapeutic antibodies
2026 · Seiya Ohki, Tomoki Fukatsu, et al. · Fluids and Barriers of the CNS · 1
Translational applicability of human blood-brain barrier spheroid models for the development of brain-penetrant therapeutic antibodies
2026 · Ohki, Seiya, Fukatsu, Tomoki, et al. · Figshare
Additional file 1 of Translational applicability of human blood-brain barrier spheroid models for the development of brain-penetrant therapeutic antibodies
2026 · Ohki, Seiya, Fukatsu, Tomoki, et al. · Figshare
Recovery of retinal function in MPS II mice by treatment with pabinafusp alfa
2024 · Atsushi Imakiire, Hideto Morimoto, et al. · Molecular Genetics and Metabolism
Life-span extension in Krabbe disease mice by treatment with a transferrin receptor-targeted galactocerebrosidase
2023 · Atsushi Imakiire, Yasunori Sugano, et al. · Molecular Genetics and Metabolism
Intravenous treatment with pabinafusp alfa dose-dependently prevents neurological impairment and bone deformities in a mouse model of mucopolysaccharidosis type II
2023 · Hideto Morimoto, Hiroki Morioka, et al. · Molecular Genetics and Metabolism
Nonclinical pharmacodynamics, pharmacokinetics and safety profiles of anti-human transferrin receptor antibody-fused N-sulfoglucosamine sulfohydrolase for mucopolysaccharidosis type IIIA
2023 · Asuka Inoue, Jun Ito, et al. · Molecular Genetics and Metabolism
Efficacy of an anti-human transferrin receptor antibody-fused N-sulfoglucosamine sulfohydrolase in mucopolysaccharidosis type IIIA mice
2022 · Asuka Inoue, Satowa Tanaka, et al. · Molecular Genetics and Metabolism
Suppression of anti-alpha-GalA antibody production by blockade of T-cell costimulation in mice
2022 · Tomoki Fukatsu, Atsushi Imakiire, et al. · Molecular Genetics and Metabolism
Non-clinical evaluation of a blood-brain barrier-penetrable N-sulfoglucosamine sulfohydrolase in a mouse model of mucopolysaccharidosis type IIIA
2021 · Satowa Tanaka, Sachiho Kida, et al. · Molecular Genetics and Metabolism
Non-clinical evaluation of a blood-brain barrier-penetrable a--acetylglucosaminidase in a mouse model of mucopolysaccharidosis type IIIB
2021 · Atsushi Imakiire, Saki Fujiyama, et al. · Molecular Genetics and Metabolism
Works count: 17
Citation count: 91
H-index: 5
I10-index: 4
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