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Can Hekim
Observed name:
C. Hekim
Observed institutions:
University of Minnesota,
University of Helsinki,
University of Eastern Finland,
Helsinki University Hospital,
Orion Corporation (Finland),
Masonic Cancer Center,
Orion Corporation (United Kingdom)
show all 7
ORCID:
0000-0003-1665-4941
Observed ORCID:
0000-0003-1665-4941
OpenAlex ID:
A5007208417
Thymic regulatory T cells arise via two distinct developmental programs
2019
·
David L. Owen
, Shawn A. Mahmud
, et al.
·
Nature Immunology
·
248
Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models
2017
·
Can Hekim
, Mette Ilander
, et al.
·
Cancer Immunology Research
·
51
Combining nilotinib and PD-L1 blockade reverses CD4+ T-cell dysfunction and prevents relapse in acute B-cell leukemia
2022
·
Sean I Tracy
, Hrishi Venkatesh
, et al.
·
Blood
·
49
PDF
Activity and stability of human kallikrein‐2‐specific linear and cyclic peptide inhibitors
2007
·
Miikka Pakkala
, Can Hekim
, et al.
·
Journal of Peptide Science
·
49
Novel Peptide Inhibitors of Human Kallikrein 2
2006
·
Can Hekim
, Jari Leinonen
, et al.
·
Journal of Biological Chemistry
·
49
PDF
Proteolytic Activity of Prostate-Specific Antigen (PSA) towards Protein Substrates and Effect of Peptides Stimulating PSA Activity
2014
·
Johanna M. Mattsson
, Suvi Ravela
, et al.
·
PLoS ONE
·
41
PDF
Immunology and Immunotherapy of Chronic Myeloid Leukemia
2014
·
Mette Ilander
, Can Hekim
, et al.
·
Current Hematologic Malignancy Reports
·
32
Development of peptides specifically modulating the activity of KLK2 and KLK3
2008
·
Hannu Koistinen
, Ale Närvänen
, et al.
·
Biological Chemistry
·
32
Mimetics of the disulfide bridge between the N- and C-terminal cysteines of the KLK3-stimulating peptide B-2
2009
·
Miikka Pakkala
, Janne Weisell
, et al.
·
Amino Acids
·
16
Identification of IGFBP-3 fragments generated by KLK2 and prevention of fragmentation by KLK2-inhibiting peptides
2010
·
Can Hekim
, Tero Riipi
, et al.
·
Biological Chemistry
·
15
Pseudopeptides with a centrally positioned alkene-based disulphide bridge mimetic stimulate kallikrein-related peptidase 3 activity
2013
·
Kristian Meinander
, Janne Weisell
, et al.
·
MedChemComm
·
9
PDF
Effect of Incubation Time on Recognition of Various Forms of Prolactin in Serum by the DELFIA Assay
2002
·
Can Hekim
, Henrik Alfthan
, et al.
·
Clinical Chemistry
·
9
Evaluation of Peptides as Protease Inhibitors and Stimulators
2013
·
Hannu Koistinen
, Can Hekim
, et al.
·
Methods in molecular biology
·
4
Complex formation between human prostate‐specific antigen and protease inhibitors in mouse plasma
2009
·
Can Hekim
, Tero Riipi
, et al.
·
The Prostate
·
4
Hyperprolactinaemia does not always mean ‘hyperprolactinaemia’!
2004
·
Altay Gezer
, Turgay Atasü
, et al.
·
European Journal of Obstetrics & Gynecology and Reproductive Biology
·
4
321 PD-L1 checkpoint blockade eradicates residual leukemia in a mouse model of acute lymphoblastic leukemia by countering exhaustion of cytotoxic and effector CD4+ T-cells
2021
·
Sean Tracy
, Hrishi Venkatesh
, et al.
·
Journal for ImmunoTherapy of Cancer
·
1
PDF
375 Simultaneous blocking of PVRIG and PD-L1 demonstrated enhanced immune activation and anti-tumour efficacy in pre-clinical mouse tumour models
2026
·
Anil K Thotakura
, Can Hekim
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
Stabilizing Long CARs for Optimal Anti-Tumor Responses in Hematological Malignancies
2025
·
Jan Koski
, Henrik Paavilainen
, et al.
·
Research Square
PDF
Abstract 4223: The dual immunestimulatory and immunesuppressive role of MRC5 fibroblast cells in 3D coculture with T cells and tumor cells
2024
·
Ilona Arnkil
, Can Hekim
, et al.
·
Cancer Research
Abstract 47: Stabilization of long CAR T cells is crucial for in vivo antitumor efficacy
2024
·
Henrik Paavilainen
, Jan Koski
, et al.
·
Cancer Research
B cell leukemia elicits a suppressive Tr1-like CD4 T cell response that can be reversed with anti-PDL1-blockade
2023
·
Hrishi Venkatesh
, Sean I Tracy
, et al.
·
The Journal of Immunology
PDF
Supplementary figures S1-S7 and Supplementary tables S1-S2 from Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models
2023
·
Can Hekim
, Mette Ilander
, et al.
PDF
Data from Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models
2023
·
Can Hekim
, Mette Ilander
, et al.
Data from Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models
2023
·
Can Hekim
, Mette Ilander
, et al.
Targeted Chemotherapy and Checkpoint Blockade Mediate Synergistic Protection Against BCR-ABL+ B Cell Leukemia
2021
·
Hrishi Venkatesh
, Sean I Tracy
, et al.
·
The Journal of Immunology
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Works count:
35
Citation count:
613
H-index:
10
I10-index:
10
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