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Keerthana Sekar
Institution:
IGM Biosciences (United States)
Observed institutions:
Amgen (United States),
IGM Biosciences (United States)
ORCID:
0009-0004-3651-4756
Observed ORCID:
0009-0004-3651-4756
OpenAlex ID:
A5007503846
IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
·
Cancer Immunology Research
·
6
PDF
CD123 Directed IgM Antibody-based T-cell Engager, IGM-2537, Demonstrates Potent in vitro and in vivo Activity with Minimal Cytokine Release
2022
·
Liqin Liu
, Gene Li
, et al.
·
Blood
·
2
Abstract 2933: Novel CD123xCD3 bispecific IgM antibody, IGM-2537, potently induces T-cell mediated cytotoxicity of acute myeloid leukemia cells with minimal cytokine release
2023
·
Gene Li
, Ling Wang
, et al.
·
Cancer Research
·
1
Abstract 5660: IGM-7354, an immunocytokine with IL-15 fused to an anti-PD-L1 IgM, induces NK and CD8+ T cell mediated cytotoxicity of PD-L1-positive tumor cells
2023
·
Thierry D. Giffon
, Melanie Desbois
, et al.
·
Cancer Research
·
1
Figure S1 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S12 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
Figure S7 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S9 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S3 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S2 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Data from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
Supplementary Table S1 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
Figure S5 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S8 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S4 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S11 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S10 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Figure S6 from IGM-7354, an Immunocytokine with IL15 Fused to an Anti–PD-L1 IgM, Induces NK and CD8+ T cell–Mediated Cytotoxicity of PD-L1–Positive Tumor Cells
2025
·
Mélanie Desbois
, Thierry Giffon
, et al.
PDF
Abstract 3438: Enhanced NK and CD8+ T cell proliferation, tumor cytotoxicity and reversal of T cell exhaustion with IGM-7354, an anti-PD-L1 IgM antibody and IL-15 cytokine fusion
2022
·
Thierry Giffon
, Melanie Desbois
, et al.
·
Cancer Research
Discovery screen platform for co-modulators of T cell effector function against tumors
2018
·
Edward Kim
, Keerthana Sekar
, et al.
·
The Journal of Immunology
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Works count:
20
Citation count:
10
H-index:
2
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