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Nicholas Favalli

Observed names: Favalli, Nicholas, N Favalli, N. Favalli
ORCID: 0000-0002-6538-7379
Observed ORCID: 0000-0002-6538-7379
OpenAlex ID: A5007857615
DNA ‐encoded chemical libraries – achievements and remaining challenges
2018 · Nicholas Favalli, Gabriele Bassi, et al. · FEBS Letters · 180
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Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries
2016 · Yizhou Li, Elena Gabriele, et al. · ACS Combinatorial Science · 130
Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications
2021 · Nicholas Favalli, Gabriele Bassi, et al. · Nature Chemistry · 72
Screening of Three Transition Metal‐Mediated Reactions Compatible with DNA‐Encoded Chemical Libraries
2019 · Nicholas Favalli, Gabriele Bassi, et al. · Helvetica Chimica Acta · 56
A DNA‐Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition
2018 · Nicholas Favalli, Stefan Biendl, et al. · ChemMedChem · 53
A Single‐Stranded DNA‐Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks
2020 · Gabriele Bassi, Nicholas Favalli, et al. · Advanced Science · 49
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Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library
2022 · Sara Puglioli, Eleonore Schmidt, et al. · Chem · 47
Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics
2022 · Laura Lucaroni, Tony Georgiev, et al. · European Journal of Nuclear Medicine and Molecular Imaging · 45
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition
2023 · Sebastian Oehler, Laura Lucaroni, et al. · Nature Chemistry · 44
Large screening of DNA-compatible reaction conditions for Suzuki and Sonogashira cross-coupling reactions and for reverse amide bond formation
2021 · Nicholas Favalli, Gabriele Bassi, et al. · Bioorganic & Medicinal Chemistry · 35
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Affinity Selections of DNA‐Encoded Chemical Libraries on Carbonic Anhydrase IX‐Expressing Tumor Cells Reveal a Dependence on Ligand Valence
2021 · Sebastian Oehler, Marco Catalano, et al. · Chemistry - A European Journal · 34
Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody
2022 · Lisa Nadal, Frederik Peissert, et al. · Journal for ImmunoTherapy of Cancer · 31
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Discovery of high-affinity ligands for prostatic acid phosphatase via DNA-encoded library screening enables targeted cancer therapy
2025 · Tony Georgiev, Francesca Migliorini, et al. · Nature Biomedical Engineering · 30
Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format
2020 · Gabriele Bassi, Nicholas Favalli, et al. · Biochemical and Biophysical Research Communications · 27
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Efficient combinatorial adaptor-mediated targeting of acute myeloid leukemia with CAR T-cells
2024 · Laura Volta, Renier Myburgh, et al. · Leukemia · 25
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Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries
2023 · Wen Torng, Ilaria Biancofiore, et al. · ACS Omega · 25
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Specific Inhibitor of Placental Alkaline Phosphatase Isolated from a DNA-Encoded Chemical Library Targets Tumor of the Female Reproductive Tract
2021 · Gabriele Bassi, Nicholas Favalli, et al. · Journal of Medicinal Chemistry · 21
Impact of Ligand Size and Conjugation Chemistry on the Performance of Universal Chimeric Antigen Receptor T-Cells for Tumor Killing
2020 · Christian Pellegrino, Nicholas Favalli, et al. · Bioconjugate Chemistry · 20
Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands
2020 · Marco Catalano, Sebastian Oehler, et al. · Analytical Chemistry · 17
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Peptide-guided adaptor-CAR T-Cell therapy for the treatment of SSTR2-expressing neuroendocrine tumors
2024 · Christian Pellegrino, Nicholas Favalli, et al. · OncoImmunology · 16
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Impact of library input on the hit discovery rate in DNA-encoded chemical library selections
2023 · Sara Puglioli, Sebastian Oehler, et al. · Chemical Science · 12
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Discovery of Glutamate Carboxypeptidase III Ligands to Compete the Uptake of [ 177 Lu]Lu-PSMA-617 in Healthy Organs
2024 · Marco Müller, Laura Lucaroni, et al. · Journal of Medicinal Chemistry · 11
Science of Synthesis
2015 · J. Scheuermann, Y. Li, et al. · Science of synthesis · 11
Structural insights into the interaction of three Y-shaped ligands with PI3Kα
2023 · Qingtong Zhou, Xiao Liu, et al. · Proceedings of the National Academy of Sciences · 9
DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target
2024 · Laura Lucaroni, Sebastian Oehler, et al. · Chemical Science · 8
Works count: 49
Citation count: 1,032
H-index: 18
I10-index: 23
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