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Heather D. Durham

Observed names: Durham, Heather, Durham, Heather Dale, H D Durham, H DURHAM, H Durham, H. D. DURHAM, H. D. Durham, H.D. Durham, HD Durham, Heather D Durham, Heather Durham
Observed institutions: Western University, Montreal Neurological Institute and Hospital, Howard Hughes Medical Institute, University of Washington, HUN-REN Szegedi Biológiai Kutatóközpont, University of Rochester Medicine, Hôpital du Saint-Sacrement, Institute of Biochemistry, Université Laval, Robarts Research Institute, McGill University, University of Rochester, Hungarian Academy of Sciences
ORCID: 0000-0001-8692-6055
Observed ORCID: 0000-0001-8692-6055
OpenAlex ID: A5007964844
Neuroblastoma × spinal cord (NSC) hybrid cell lines resemble developing motor neurons
1992 · Neil R. Cashman, Heather D. Durham, et al. · Developmental Dynamics · 723
Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo
2009 · Edor Kabashi, Li Lin, et al. · Human Molecular Genetics · 415
Aggregation of Mutant Cu/Zn Superoxide Dismutase Proteins in a Culture Model of ALS
1997 · H. D. DURHAM, J. ROY, et al. · Journal of Neuropathology & Experimental Neurology · 349
Neurofilaments: neurobiological foundations for biomarker applications
2020 · Arie R Gafson, Nicolas R Barthélemy, et al. · Brain · 326
High Threshold for Induction of the Stress Response in Motor Neurons Is Associated with Failure to Activate HSF1
2003 · Zarah Batulan, Gayle A. Shinder, et al. · Journal of Neuroscience · 269
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Up‐Regulation of Protein Chaperones Preserves Viability of Cells Expressing Toxic Cu/Zn‐Superoxide Dismutase Mutants Associated with Amyotrophic Lateral Sclerosis
1999 · Wendy Bruening, Josée Roy, et al. · Journal of Neurochemistry · 263
Glutamate Potentiates the Toxicity of Mutant Cu/Zn-Superoxide Dismutase in Motor Neurons by Postsynaptic Calcium-Dependent Mechanisms
1998 · Josée Roy, Sandra Minotti, et al. · Journal of Neuroscience · 231
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Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations
2011 · Miranda L. Tradewell, Zhenbao Yu, et al. · Human Molecular Genetics · 212
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Mutant Cu/Zn-Superoxide Dismutase Proteins Have Altered Solubility and Interact with Heat Shock/Stress Proteins in Models of Amyotrophic Lateral Sclerosis
2001 · Gayle A. Shinder, Marie-Claude Lacourse, et al. · Journal of Biological Chemistry · 202
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Progranulin is expressed within motor neurons and promotes neuronal cell survival
2009 · Cara L Ryan, David C Baranowski, et al. · BMC Neuroscience · 160
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TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types
2018 · Yousra Khalfallah, Rachel Kuta, et al. · Scientific Reports · 159
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Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis
2004 · Edor Kabashi, Jeffrey N. Agar, et al. · Journal of Neurochemistry · 153
A neurotoxic peripherin splice variant in a mouse model of ALS
2003 · Janice Robertson, Mohammad M. Doroudchi, et al. · The Journal of Cell Biology · 126
Evaluation of the spinal cord neuron X neuroblastoma hybrid cell line NSC-34 as a model for neurotoxicity testing.
1993 · H D Durham, S Dahrouge, et al. · PubMed · 124
Induction of multiple heat shock proteins and neuroprotection in a primary culture model of familial amyotrophic lateral sclerosis
2006 · Zarah Batulan, David M. Taylor, et al. · Neurobiology of Disease · 116
Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-α
2001 · Janice Robertson, Jean-Martin Beaulieu, et al. · The Journal of Cell Biology · 116
Optimized protocols for isolation of primary motor neurons, astrocytes and microglia from embryonic mouse spinal cord
2007 · Marie Gingras, Vicky Gagnon, et al. · Journal of Neuroscience Methods · 108
Neurofilament dynamics and involvement in neurological disorders
2015 · Benoit J. Gentil, Michael Tibshirani, et al. · Cell and Tissue Research · 100
In vitro study of axonal migration and myelination of motor neurons in a three‐dimensional tissue‐engineered model
2007 · Marie Gingras, Marie‐Michèle Beaulieu, et al. · Glia · 96
Relevance of oxidative injury in the pathogenesis of motor neuron diseases
2003 · Jeff Agar, Heather Durham · Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders · 95
Sacs knockout mice present pathophysiological defects underlying autosomal recessive spastic ataxia of Charlevoix-Saguenay
2014 · Roxanne Larivière, Rébecca Gaudet, et al. · Human Molecular Genetics · 94
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Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter
1998 · W. Bruening, B. Giasson, et al. · Nucleic Acids Research · 91
Failure of protein quality control in amyotrophic lateral sclerosis
2006 · Edor Kabashi, Heather D. Durham · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 90
The principles of gene therapy for the nervous system
1996 · George Karpati, Hanns Lochmüller, et al. · Trends in Neurosciences · 88
Tryptophan 32 Potentiates Aggregation and Cytotoxicity of a Copper/Zinc Superoxide Dismutase Mutant Associated with Familial Amyotrophic Lateral Sclerosis
2007 · David M. Taylor, Bernard F. Gibbs, et al. · Journal of Biological Chemistry · 85
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Works count: 110
Citation count: 6,375
H-index: 39
I10-index: 73
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