Get started
Author

Stefania Colarusso

Observed name: S. Colarusso
Institution: IRBM
ORCID: 0000-0003-3806-6999
Observed ORCID: 0000-0003-3806-6999
OpenAlex ID: A5008091097
A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease
2002 · Frank Narjes, Konrad F Koehler, et al. · Bioorganic & Medicinal Chemistry Letters · 189
Inhibition of the Hepatitis C Virus NS3/4A Protease
2000 · Stefania Di Marco, Menico Rizzi, et al. · Journal of Biological Chemistry · 128
PDF
2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase: Discovery, SAR, Modeling, and Mutagenesis
2006 · Uwe Koch, Barbara Attenni, et al. · Journal of Medicinal Chemistry · 89
α-Ketoacids Are Potent Slow Binding Inhibitors of the Hepatitis C Virus NS3 Protease
2000 · Frank Narjes, Mirko Brunetti, et al. · Biochemistry · 76
Discovery of (7R)-14-Cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic Acid (MK-3281), a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase
2010 · Frank Narjes, Benedetta Crescenzi, et al. · Journal of Medicinal Chemistry · 67
Evolution, synthesis and SAR of tripeptide α-ketoacid Inhibitors of the hepatitis C virus NS3/NS4A serine protease
2002 · Stefania Colarusso, Benjamin Gerlach, et al. · Bioorganic & Medicinal Chemistry Letters · 53
Katritzky Salts for the Synthesis of Unnatural Amino Acids and Late‐Stage Functionalization of Peptides
2022 · Ali Munaim Yousif, Stefania Colarusso, et al. · European Journal of Organic Chemistry · 40
Active site inhibitors of HCV NS5B polymerase. The development and pharmacophore of 2-thienyl-5,6-dihydroxypyrimidine-4-carboxylic acid
2004 · Ian Stansfield, Salvatore Avolio, et al. · Bioorganic & Medicinal Chemistry Letters · 40
Phenethyl Amides as Novel Noncovalent Inhibitors of Hepatitis C Virus NS3/4A Protease: Discovery, Initial SAR, and Molecular Modeling
2002 · Stefania Colarusso, Uwe Koch, et al. · Journal of Medicinal Chemistry · 40
Combined Peptide and Small-Molecule Approach toward Nonacidic THIQ Inhibitors of the KEAP1/NRF2 Interaction
2020 · Jesus M. Ontoria, Ilaria Biancofiore, et al. · ACS Medicinal Chemistry Letters · 32
Optimization of Thienopyrrole‐Based Finger‐Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase
2009 · Jose Ignacio Martin Hernando, Jesus Maria Ontoria, et al. · ChemMedChem · 31
Optimization of linear and cyclic peptide inhibitors of KEAP1-NRF2 protein-protein interaction
2020 · Stefania Colarusso, Daniele De Simone, et al. · Bioorganic & Medicinal Chemistry · 29
SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease
2004 · Savina Malancona, Stefania Colarusso, et al. · Bioorganic & Medicinal Chemistry Letters · 23
Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain
2021 · Gregory L. Adams, Parul S. Pall, et al. · Journal of Medicinal Chemistry · 21
SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease
2022 · Stefania Colarusso, Federica Ferrigno, et al. · Bioorganic & Medicinal Chemistry · 11
Development of a Scalable Chiral Synthesis of MK-3281, an Inhibitor of the Hepatitis C Virus NS5B Polymerase
2011 · Stefania Colarusso, Jörg Habermann, et al. · Synlett · 10
Guiding Chemically Synthesized Peptide Drug Lead Optimization by Derisking Mast Cell Degranulation-Related Toxicities of a NaV1.7 Peptide Inhibitor
2021 · Pierre Morissette, Nianyu Li, et al. · Toxicological Sciences · 7
Inhibitors of the hepatitis C virus RNA-dependent RNA polymerase
2006 · Barbara Attenni, Salvatore Avolio, et al. · ARKIVOC · 7
PDF
Suzuki Coupling at the 2-Position of Densely Functionalized Pyrimidones
2006 · Stefania Colarusso, Mélina Girardin, et al. · Synthesis · 4
Discovery and Optimization of an mRNA Display Cyclic Peptide inhibitor of the IL1b/IL1R Interaction
2026 · Stefania Colarusso, Francesca Pavone, et al. · European Peptide Symposium (EPS)
PDF
Front Cover: Katritzky Salts for the Synthesis of Unnatural Amino Acids and Late‐Stage Functionalization of Peptides (Eur. J. Org. Chem. 12/2023)
2023 · Ali Munaim Yousif, Stefania Colarusso, et al. · European Journal of Organic Chemistry
PDF
Keap1 in Complex With Compound 44
2019 · S. Colarusso · Worldwide Protein Data Bank
a Potent and Orally Bioavailable Finger-Loop Inhibitor of the Hepatitis C Virus NS5B Polymerase
2011 · Frank Narjes, Benedetta Crescenzi, et al.
Suzuki Coupling at the 2‐Position of Densely Functionalized Pyrimidones.
2006 · Stefania Colarusso, Melina Girardin, et al. · ChemInform
The Role of an Amphiphilic Capping Group in Covalent and Non-Covalent Dipeptide Inhibitors of HCV NS3 Serine Protease
2005 · Stefania Colarusso, Benjamin Gerlach, et al. · Letters in Drug Design & Discovery
Works count: 27
Citation count: 897
H-index: 14
I10-index: 16
Year
Topic
Type