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Lola Lecru

SIRT1 protects the heart from ER stress-induced cell death through eIF2α deacetylation
2016 · Alexandre Prola, Julie Pires Da Silva, et al. · Cell Death and Differentiation · 223
Cannabinoid receptor 1 is a major mediator of renal fibrosis
2015 · Lola Lecru, Christophe Desterke, et al. · Kidney International · 130
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Interleukin-15 Plays a Central Role in Human Kidney Physiology and Cancer through the γc Signaling Pathway
2012 · Julien Giron-Michel, Sandy Azzi, et al. · PLoS ONE · 39
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Circulating CASK is associated with recurrent focal segmental glomerulosclerosis after transplantation
2019 · Severine Beaudreuil, Xiaomeng Zhang, et al. · PLoS ONE · 34
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The Role of Cannabinoid Receptors in Renal Diseases
2018 · Helene Francois, Lola Lecru · Current Medicinal Chemistry · 28
IL-15 Prevents Renal Fibrosis by Inhibiting Collagen Synthesis: A New Pathway in Chronic Kidney Disease?
2021 · Aurore Devocelle, Lola Lecru, et al. · International Journal of Molecular Sciences · 26
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Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis
2019 · Aurore Devocelle, Lola Lecru, et al. · International Journal of Cell Biology · 25
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Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases
2021 · Oscar Mammoliti, Koen Jansen, et al. · Journal of Medicinal Chemistry · 22
The cannabinoid receptor 1 is involved in renal fibrosis during chronic allograft dysfunction: Proof of concept
2019 · Myriam Dao, Lola Lecru, et al. · Journal of Cellular and Molecular Medicine · 22
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ADAMTS-5 inhibition reduces muscle inflammation and fibrosis and improves function in mouse models of Duchenne muscular dystrophy
2025 · John Dulos, Danielle A. Debruin, et al. · Science Translational Medicine · 5
Rôle des récepteurs cannabinoïdes au cours des maladies rénales
2016 · Hélène François, Antoine Durrbach, et al. · Néphrologie & Thérapeutique · 4
Abstract 2020: Fibroblast derived type III collagen pro-peptides (PRO-C3) in plasma is associated with outcome for patients with NSCLC treated with anti-PD1 plus chemotherapy
2025 · Nicholas Willumsen, Lola Lecru, et al. · Cancer Research · 2
Abstract 3276: Clinical PK, PD and safety analysis of a phase I clinical trial of DT-9081, an EP4R-antagonist, for RP2D determination in patients with advanced solid tumours
2025 · Christophe Le Tourneau, Zahra Castel-Ajgal, et al. · Cancer Research · 2
Discovery of DT-9081, a Potent and Orally Bioavailable Small Molecule Antagonist of the EP4 Receptor for the Treatment of Solid Cancers
2026 · Anne-Laure Blayo, Gaël Hommet, et al. · Journal of Medicinal Chemistry · 1
Targeting PAR-2 with a negative allosteric modulator increases tumor antigen presentation and potentiates anti-PD-1 immunotherapy
2026 · Samya Aouad, Maleck Kadiri, et al. · Journal for ImmunoTherapy of Cancer · 1
Interleukine-15 : une nouvelle voie thérapeutique potentielle de la fibrose rénale
2015 · L. Lecru, A. Devocelle, et al. · Néphrologie & Thérapeutique · 1
First-in-human phase I study of DT-9081, a selective EP4 receptor antagonist, in advanced solid tumors
2026 · Rachel Galot, Zahra Castel-Ajgal, et al. · Investigational New Drugs
Tu2021 ELAFIBRANOR-ASSOCIATED CHANGES IN PROTEINS LINKED TO MITOCHONDRIAL FUNCTION CORRELATE WITH FATIGUE IMPROVEMENT: PROTEOMIC RESULTS FROM THE ELATIVE® TRIAL
2026 · Mark G. Swain, Maria D. Schneider, et al. · Gastroenterology
Tu2021 ELAFIBRANOR-ASSOCIATED CHANGES IN PROTEINS LINKED TO MITOCHONDRIAL FUNCTION CORRELATE WITH FATIGUE IMPROVEMENT: PROTEOMIC RESULTS FROM THE ELATIVE® TRIAL
2026 · Mark G. Swain, Maria D. Schneider, et al. · Gastrointestinal Endoscopy
Abstract 5239: Biomarker dynamics in the completed phase I study of DT-9081: An analysis of ex vivo cytokine stimulation, urinary PGEM, and tumoral biomarkers in advanced solid tumors
2026 · Thomas Maurin, Lola Lecru, et al. · Cancer Research
135 - Elafibranor-associated Changes in Proteins Linked to Mitochondrial Function Correlate With Fatigue Improvement: Proteomic Results From the Elative® Trial
2026 · Álvaro Díaz-González, Mark G. Swain, et al. · Gastroenterología y Hepatología
CCDC 2122384: Experimental Crystal Structure Determination
2021 · Mammoliti, Oscar, Jansen, Koen, et al. · The Cambridge Structural Database
CCDC 2122349: Experimental Crystal Structure Determination
2021 · Mammoliti, Oscar, Jansen, Koen, et al. · The Cambridge Structural Database
Le rôle des récepteurs cannabinoïdes dans la dysfonction chronique de l’allogreffe
2018 · M. Dao, L. Lecru, et al. · Néphrologie & Thérapeutique
SIRT1 protects the heart from endoplasmic reticulum stress-induced apoptosis through eIF2α deacetylation
2017 · J. Pires da Silva, A. Prola, et al. · Archives of Cardiovascular Diseases Supplements
Works count: 30
Citation count: 565
H-index: 9
I10-index: 9
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