Get started
Author

Tomoharu Kuboyama

Observed name: Kuboyama Tomoharu
Observed institutions: RIKEN Center for Brain Science, Daiichi University of Pharmacy, RIKEN, University of Toyama, Institute of Natural Medicine, University of Toyama, Icahn School of Medicine at Mount Sinai
ORCID: 0000-0003-3037-9974
Observed ORCID: 0000-0003-3037-9974
OpenAlex ID: A5008647714
Neuritic regeneration and synaptic reconstruction induced by withanolide A
2005 · Tomoharu Kuboyama, Chihiro Tohda, et al. · British Journal of Pharmacology · 355
PDF
Search for Natural Products Related to Regeneration of the Neuronal Network
2005 · Chihiro Tohda, Tomoharu Kuboyama, et al. · Neurosignals · 261
Withanolide Derivatives from the Roots of Withania somnifera and Their Neurite Outgrowth Activities.
2002 · Jing Zhao, Norio Nakamura, et al. · Chemical and Pharmaceutical Bulletin · 195
PDF
Withanoside IV and its active metabolite, sominone, attenuate Aβ(25–35)‐induced neurodegeneration
2006 · Tomoharu Kuboyama, Chihiro Tohda, et al. · European Journal of Neuroscience · 178
Diosgenin is an exogenous activator of 1,25D3-MARRS/Pdia3/ERp57 and improves Alzheimer's disease pathologies in 5XFAD mice
2012 · Chihiro Tohda, Takuya Urano, et al. · Scientific Reports · 174
PDF
Axon- or dendrite-predominant outgrowth induced by constituents from Ashwagandha
2002 · Tomoharu Kuboyama, Chihiro Tohda, et al. · Neuroreport · 148
Effects of Ashwagandha (Roots of Withania somnifera) on Neurodegenerative Diseases
2014 · Tomoharu Kuboyama, Chihiro Tohda, et al. · Biological and Pharmaceutical Bulletin · 134
PDF
Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells
2000 · Chihiro Tohda, Tomoharu Kuboyama, et al. · Neuroreport · 111
Current and future therapeutic strategies for functional repair of spinal cord injury
2011 · Chihiro Tohda, Tomoharu Kuboyama · Pharmacology & Therapeutics · 108
A Systematic Strategy for Discovering a Therapeutic Drug for Alzheimer’s Disease and Its Target Molecule
2017 · Zhiyou Yang, Tomoharu Kuboyama, et al. · Frontiers in Pharmacology · 93
PDF
Naringenin promotes microglial M2 polarization and Aβ degradation enzyme expression
2019 · Zhiyou Yang, Tomoharu Kuboyama, et al. · Phytotherapy Research · 74
HDAC3 inhibition ameliorates spinal cord injury by immunomodulation
2017 · Tomoharu Kuboyama, Shalaka Wahane, et al. · Scientific Reports · 74
PDF
Extracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth
2015 · Michiko Shigyo, Tomoharu Kuboyama, et al. · Scientific Reports · 66
PDF
Trigonelline recovers memory function in Alzheimer’s disease model mice: evidence of brain penetration and target molecule
2020 · Mai M. Farid, Ximeng Yang, et al. · Scientific Reports · 61
PDF
A novel compound, denosomin, ameliorates spinal cord injury via axonal growth associated with astrocyte‐secreted vimentin
2012 · Kiyoshi Teshigawara, Tomoharu Kuboyama, et al. · British Journal of Pharmacology · 59
PDF
Kamikihi-to (KKT) Rescues Axonal and Synaptic Degeneration Associated with Memory Impairment in a Mouse Model of Alzheimer's Disease, 5XFAD
2011 · Chihiro Tohda, Rie Nakada, et al. · International Journal of Neuroscience · 50
Polygalae Radix Extract Prevents Axonal Degeneration and Memory Deficits in a Transgenic Mouse Model of Alzheimer’s Disease
2017 · Tomoharu Kuboyama, Keisuke Hirotsu, et al. · Frontiers in Pharmacology · 42
PDF
A Novel Rac1-GSPT1 Signaling Pathway Controls Astrogliosis Following Central Nervous System Injury
2016 · Taiji Ishii, Takehiko Ueyama, et al. · Journal of Biological Chemistry · 41
PDF
Active Constituents from Drynaria fortunei Rhizomes on the Attenuation of Aβ 25–35 -Induced Axonal Atrophy
2015 · Zhi-You Yang, Tomoharu Kuboyama, et al. · Journal of Natural Products · 34
Memory Enhancement by Oral Administration of Extract of Eleutherococcus senticosus Leaves and Active Compounds Transferred in the Brain
2019 · Yui Yamauchi, Yue-Wei Ge, et al. · Nutrients · 33
PDF
Matrine Directly Activates Extracellular Heat Shock Protein 90, Resulting in Axonal Growth and Functional Recovery in Spinal Cord Injured-Mice
2018 · Norio Tanabe, Tomoharu Kuboyama, et al. · Frontiers in Pharmacology · 31
PDF
Inhibition of clathrin-mediated endocytosis prevents amyloid β-induced axonal damage
2015 · Tomoharu Kuboyama, Young-A. Lee, et al. · Neurobiology of Aging · 27
New reliable scoring system, Toyama mouse score, to evaluate locomotor function following spinal cord injury in mice
2014 · Michiko Shigyo, Norio Tanabe, et al. · BMC Research Notes · 27
PDF
Combined Treatment with Two Water Extracts of Eleutherococcus senticosus Leaf and Rhizome of Drynaria fortunei Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind Study in Healthy Adults
2020 · Chihiro Tohda, Mie Matsui, et al. · Nutrients · 22
PDF
Recovery from spinal cord injury via M2 microglial polarization induced by Polygalae Radix
2020 · Tomoharu Kuboyama, Seiya Kominato, et al. · Phytomedicine · 21
Works count: 60
Citation count: 2,578
H-index: 23
I10-index: 32
Year
Topic
Type