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Nathaniel T. Burkholder

Observed names: Burkholder, Nathaniel Tate, N.T. Burkholder, Nathanial T. Burkholder, Nathaniel T Burkholder, Nathaniel Tate Burkholder
ORCID: 0000-0002-1769-3750
Observed ORCID: 0000-0002-1769-3750
OpenAlex ID: A5008817259
Using fungible biosensors to evolve improved alkaloid biosyntheses
2022 · Simon d’Oelsnitz, Wantae Kim, et al. · Nature Chemical Biology · 95
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TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons
2023 · Shuai Zhao, Jiuwei Lu, et al. · Nature · 66
Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
2019 · Joshua E. Mayfield, Seema Irani, et al. · eLife · 44
Dephosphorylating eukaryotic RNA polymerase II
2016 · Joshua E. Mayfield, Nathaniel T. Burkholder, et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 34
Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST)
2018 · Nathaniel Tate Burkholder, Joshua E. Mayfield, et al. · Journal of Biological Chemistry · 24
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Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme
2022 · John Blazeck, Christos S. Karamitros, et al. · Nature Catalysis · 22
Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription
2019 · Seema Irani, Sarah N. Sipe, et al. · Journal of Biological Chemistry · 15
Mapping RNAPII CTD Phosphorylation Reveals That the Identity and Modification of Seventh Heptad Residues Direct Tyr1 Phosphorylation
2019 · Nathaniel T. Burkholder, Sarah N. Sipe, et al. · ACS Chemical Biology · 9
The bromo-adjacent homology domains of PBRM1 associate with histone tails and contribute to PBAF-mediated gene regulation
2023 · Christopher J. Petell, Nathaniel T. Burkholder, et al. · Journal of Biological Chemistry · 6
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The ZZ domain of HERC2 is a receptor of arginylated substrates
2022 · Adam H. Tencer, Jiuyang Liu, et al. · Scientific Reports · 4
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HMGN1 and HMGN2 are recruited to acetylated and histone variant H2A.Z-containing nucleosomes to regulate chromatin state and transcription
2025 · Riya Gohil, Zhihan Gao, et al. · Journal of Biological Chemistry · 2
Chemical Tools for Studying the Impact of cis/trans Prolyl Isomerization on Signaling: A Case Study on RNA Polymerase II Phosphatase Activity and Specificity
2018 · Nathaniel Tate Burkholder, Brenda Medellin, et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 2
Structural basis of RNA Polymerase II C-terminal domain kinase and phosphatase specificity and their impact on transcriptional regulation
2019 · Burkholder, Nathaniel Tate · 1
Modification of Ser 7 of the RNA Polymerase II C‐terminal domain (CTD) regulates CTD phosphorylation patterns and transcription
2019 · Nathaniel Tate Burkholder, Sarah Sipe, et al. · The FASEB Journal · 1
Tandem bromodomains of BRD4 cooperatively read poly-acetylated nucleosomes to enhance chromatin engagement and regulate breast cancer phenotypes
2026 · Nathaniel T Burkholder, Shwu-Yuan Wu, et al. · bioRxiv (Cold Spring Harbor Laboratory)
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Author response: Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
2019 · Joshua E Mayfield, Seema Irani, et al. · eLife
Structure of Scp1 D96N bound to REST-pS861/4 peptide
2018 · N.T. Burkholder, J.E. Mayfield, et al. · Worldwide Protein Data Bank
Tyr1 phosphorylation of RNA polymerase II CTD directs and expands the CTD code.
2018 · Joshua E. Mayfield, M. Rachel Mehaffey, et al. · The FASEB Journal
Structure and function of novel RTX-like proteins BAV1944 and BAV1945 in Bordetella avium
2014 · Nathaniel T. Burkholder · JMU Scholoraly Commons (James Madison University)
Works count: 19
Citation count: 325
H-index: 8
I10-index: 7
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