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Emma Bolderson

PARP Inhibitors: Clinical Relevance, Mechanisms of Action and Tumor Resistance
2020 · Maddison Rose, Joshua T. Burgess, et al. · Frontiers in Cell and Developmental Biology · 731
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Nucleophosmin: from structure and function to disease development
2016 · Joseph K. Box, Nicolas Paquet, et al. · BMC Molecular Biology · 272
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Single-stranded DNA-binding protein hSSB1 is critical for genomic stability
2008 · Derek J. Richard, Emma Bolderson, et al. · Nature · 253
Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair
2009 · Emma Bolderson, Derek J. Richard, et al. · Clinical Cancer Research · 187
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks
2009 · Emma Bolderson, Nozomi Tomimatsu, et al. · Nucleic Acids Research · 185
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Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions
2012 · Nozomi Tomimatsu, Bipasha Mukherjee, et al. · DNA repair · 136
hSSB1 and hSSB2 Form Similar Multiprotein Complexes That Participate in DNA Damage Response
2009 · Yongjiang Li, Emma Bolderson, et al. · Journal of Biological Chemistry · 123
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Chemotherapeutic Compounds Targeting the DNA Double-Strand Break Repair Pathways: The Good, the Bad, and the Promising
2014 · Christian Jekimovs, Emma Bolderson, et al. · Frontiers in Oncology · 121
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Human single-stranded DNA binding proteins are essential for maintaining genomic stability
2013 · Nicholas W Ashton, Emma Bolderson, et al. · BMC Molecular Biology · 113
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Multiple human single-stranded DNA binding proteins function in genome maintenance: structural, biochemical and functional analysis
2009 · Derek J. Richard, Emma Bolderson, et al. · Critical Reviews in Biochemistry and Molecular Biology · 106
Rad51 supports triple negative breast cancer metastasis
2014 · Adrian P Wiegmans, Fares Al-Ejeh, et al. · Oncotarget · 105
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INTS3 controls the hSSB1-mediated DNA damage response
2009 · Jeffrey R. Skaar, Derek J. Richard, et al. · The Journal of Cell Biology · 100
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Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy
2021 · Thais Sobanski, Maddison Rose, et al. · Frontiers in Cell and Developmental Biology · 89
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ATM is required for the cellular response to thymidine induced replication fork stress
2004 · Emma Bolderson, Jennifer Scorah, et al. · Human Molecular Genetics · 86
hSSB1 rapidly binds at the sites of DNA double-strand breaks and is required for the efficient recruitment of the MRN complex
2010 · Derek J. Richard, Kienan Savage, et al. · Nucleic Acids Research · 84
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hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double-strand breaks and its endo-nuclease activity
2011 · Derek J. Richard, Liza Cubeddu, et al. · Nucleic Acids Research · 83
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ATM-dependent phosphorylation of MRE11 controls extent of resection during homology directed repair by signalling through Exonuclease 1
2015 · Amanda W. Kijas, Yi Chieh Lim, et al. · Nucleic Acids Research · 70
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Multifocal Urothelial Cancers With the Mutator Phenotype are of Monoclonal Origin and Require Panurothelial Treatment for Tumor Clearance
2006 · James W.F. Catto, Arndt Hartmann, et al. · The Journal of Urology · 70
Tumor Hypoxia Drives Genomic Instability
2021 · Ming Tang, Emma Bolderson, et al. · Frontiers in Cell and Developmental Biology · 63
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Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
2019 · Emma Bolderson, Joshua T. Burgess, et al. · Nature Communications · 61
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Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks
2014 · Emma Bolderson, Eva Petermann, et al. · Nucleic Acids Research · 58
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Beyond PARP1: The Potential of Other Members of the Poly (ADP-Ribose) Polymerase Family in DNA Repair and Cancer Therapeutics
2022 · Iain A. Richard, Joshua T. Burgess, et al. · Frontiers in Cell and Developmental Biology · 57
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The Therapeutic Potential of DNA Damage Repair Pathways and Genomic Stability in Lung Cancer
2020 · Joshua T. Burgess, Maddison Rose, et al. · Frontiers in Oncology · 53
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Krüppel-associated Box (KRAB)-associated Co-repressor (KAP-1) Ser-473 Phosphorylation Regulates Heterochromatin Protein 1β (HP1-β) Mobilization and DNA Repair in Heterochromatin
2012 · Emma Bolderson, Kienan I. Savage, et al. · Journal of Biological Chemistry · 53
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Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation
2014 · Nicolas Paquet, Joseph K Box, et al. · BMC Molecular Biology · 48
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Works count: 85
Citation count: 3,853
H-index: 32
I10-index: 46
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