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Grégory Chaume

Observed names: Chaume, G., Chaume, Gregory, Chaume, Grégory, Chaume,, C.G., G Chaume, G. Chaume, Gregory Chaume, Grégory Chaume
Observed institutions: Centre National de la Recherche Scientifique, École Polytechnique, Université Paris Sciences et Lettres, Université Paris-Saclay, École Normale Supérieure - PSL, Sorbonne Université, Laboratoire Hétéroéléments et Coordination, CY Cergy Paris Université, Laboratoire des Biomolécules, Université de Cergy-Pontoise, Biomolécules : Conception, Isolement, Synthèse, Université Pierre-et-Marie-Curie
ORCID: 0000-0001-7460-4876
Observed ORCID: 0000-0001-7460-4876
OpenAlex ID: A5009317598
Straightforward Synthesis of (S)- and (R)-α-Trifluoromethyl Proline from Chiral Oxazolidines Derived from Ethyl Trifluoropyruvate
2006 · Grégory Chaume, Marie-Céline Van Severen, et al. · Organic Letters · 81
Iodocyclization of Chiral CF3-Allylmorpholinones: A Versatile Strategy for the Synthesis of Enantiopure α-Tfm-Prolines and α-Tfm-Dihydroxyprolines
2008 · Caroline Caupène, Grégory Chaume, et al. · Organic Letters · 63
Convenient Synthesis of N ‐Terminal Tfm‐Dipeptides from Unprotected Enantiopure α‐Tfm‐Proline and α‐Tfm‐Alanine
2009 · Grégory Chaume, Nathalie Lensen, et al. · European Journal of Organic Chemistry · 58
Highly Diastereoselective α-Hydroxylation of Fox Chiral Auxiliary-Based Amide Enolates with Molecular Oxygen
2010 · Hodney Lubin, Arnaud Tessier, et al. · Organic Letters · 53
Synthesis of 2-Trifluoromethyl-1,3-oxazolidines as Hydrolytically Stable Pseudoprolines
2010 · Grégory Chaume, Olivier Barbeau, et al. · The Journal of Organic Chemistry · 52
Synthesis of an MIF-1 analogue containing enantiopure ( S )-α-trifluoromethyl-proline and biological evaluation on nociception
2013 · Ibtissem Jlalia, Nathalie Lensen, et al. · European Journal of Medicinal Chemistry · 45
Concise access to enantiopure (S)- and (R)-α-trifluoromethyl pyroglutamic acids from ethyl trifluoropyruvate-based chiral CF3-oxazolidines (Fox)
2008 · Grégory Chaume, Marie-Céline Van Severen, et al. · Journal of Fluorine Chemistry · 39
CF 2 H as a hydrogen bond donor group for the fine tuning of peptide bond geometry with difluoromethylated pseudoprolines
2019 · N. Malquin, K. Rahgoshay, et al. · Chemical Communications · 36
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Incorporation of CF3–Pseudoprolines into Peptides: A Methodological Study
2013 · Grégory Chaume, Julien Simon, et al. · The Journal of Organic Chemistry · 36
Local Control of the Cis–Trans Isomerization and Backbone Dihedral Angles in Peptides Using Trifluoromethylated Pseudoprolines
2012 · Debby Feytens, Grégory Chaume, et al. · The Journal of Physical Chemistry B · 36
Trifluoromethylated proline analogues as efficient tools to enhance the hydrophobicity and to promote passive diffusion transport of the l -prolyl- l -leucyl glycinamide (PLG) tripeptide
2018 · Martin Oliver, Charlène Gadais, et al. · RSC Advances · 35
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Synthesis of Enantiopure trans-2,5-Disubstituted Trifluoromethylpyrrolidines and (2S,5R)-5-Trifluoromethylproline
2015 · Hodney Lubin, Julien Pytkowicz, et al. · The Journal of Organic Chemistry · 31
Trifluoromethylthiolation of Tryptophan and Tyrosine Derivatives: A Tool for Enhancing the Local Hydrophobicity of Peptides
2023 · Jure Gregorc, Nathalie Lensen, et al. · The Journal of Organic Chemistry · 29
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Approach Toward the Total Synthesis of Griseoviridin: Formation of Thioethynyl and Thiovinyl Ether-Containing Nine-Membered Lactones through a Thioalkynylation−Macrolactonization−Hydrostannylation Sequence
2002 · Carine Kuligowski, Sophie Bezzenine-Lafollée, et al. · The Journal of Organic Chemistry · 29
Incorporation of Trifluoromethylated Proline and Surrogates into Peptides: Application to the Synthesis of Fluorinated Analogues of the Neuroprotective Glycine-Proline-Glutamate (GPE) Tripeptide
2016 · Julien Simon, Julien Pytkowicz, et al. · The Journal of Organic Chemistry · 27
Orthogonal 19F‐Labeling for Solid‐State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes
2018 · Stephan L. Grage, Sezgin Kara, et al. · Chemistry - A European Journal · 25
Homochiral versus Heterochiral Trifluoromethylated Pseudoproline Containing Dipeptides: A Powerful Tool to Switch the Prolyl-Amide Bond Conformation
2017 · Grégory Chaume, Julien Simon, et al. · The Journal of Organic Chemistry · 25
Concise synthesis of enantiopure (S)- and (R)-α-trifluoromethyl aspartic acid and α-trifluoromethyl serine from chiral trifluoromethyl oxazolidines (Fox) via a Strecker-type reaction
2011 · Julien Simon, Thi Thuan Nguyen, et al. · Tetrahedron Asymmetry · 21
Trifluoromethylated Proline Surrogates as Part of “Pro–Pro” Turn‐Inducing Templates
2019 · Charlène Gadais, Kevin Van holsbeeck, et al. · ChemBioChem · 19
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Introducing the Chiral Constrained α‐Trifluoromethylalanine in Aib Foldamers to Control, Quantify and Assign the Helical Screw‐Sense**
2021 · Lizeth Bodero, Karine Guitot, et al. · Chemistry - A European Journal · 18
Conformational properties of peptides incorporating a fluorinated pseudoproline residue
2013 · Grégory Chaume, Debby Feytens, et al. · New Journal of Chemistry · 18
Enantiopure 5-CF3–Proline: Synthesis, Incorporation in Peptides, and Tuning of the Peptide Bond Geometry
2020 · Clément A. Sanchez, Charlène Gadais, et al. · Organic Letters · 14
Asymmetric α-Fluoroalkyl-α-Amino Acids: Recent Advances in Their Synthesis and Applications
2024 · Nathan Picois, Yazid Boutahri, et al. · Molecules · 10
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Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations
2017 · Marina Putzu, Sezgin Kara, et al. · Biophysical Journal · 10
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Fluorinated Peptide Hydrogels Result in Longer In Vivo Residence Time after Subcutaneous Administration
2024 · Aurélie Honfroy, Jolien Bertouille, et al. · Biomacromolecules · 9
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Works count: 75
Citation count: 845
H-index: 19
I10-index: 24
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