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Rodrigo Pacheco Silva-Aguiar

Observed names: R. P. Silva-Aguiar, Rodrigo P. Silva-Aguiar, Rodrigo P. Silva‐Aguiar, Rodrigo Pacheco da Silva-Aguiar, Rodrigo Silva-Aguiar, Rodrigo Silva‐Aguiar
ORCID: 0000-0003-1975-8033
Observed ORCID: 0000-0003-1975-8033
OpenAlex ID: A5009608093
High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylation
2018 · Diogo de Barros Peruchetti, Rodrigo Pacheco Silva-Aguiar, et al. · Journal of Biological Chemistry · 60
O-GlcNAcylation reduces proximal tubule protein reabsorption and promotes proteinuria in spontaneously hypertensive rats
2018 · Rodrigo Pacheco Silva-Aguiar, Nathália C.F. Bezerra, et al. · Journal of Biological Chemistry · 55
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IL-4 Receptor α Chain Protects the Kidney Against Tubule-Interstitial Injury Induced by Albumin Overload
2020 · Diogo B. Peruchetti, João Luiz Silva-Filho, et al. · Frontiers in Physiology · 33
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Inhibition of SGLT2 co-transporter by dapagliflozin ameliorates tubular proteinuria and tubule-interstitial injury at the early stage of diabetic kidney disease
2023 · Raysa S. Farias, Rodrigo P. Silva-Aguiar, et al. · European Journal of Pharmacology · 32
Albumin Expands Albumin Reabsorption Capacity in Proximal Tubule Epithelial Cells through a Positive Feedback Loop between AKT and Megalin
2022 · Rodrigo P. Silva-Aguiar, Diogo B. Peruchetti, et al. · International Journal of Molecular Sciences · 31
Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney injury animal model
2021 · Diogo B. Peruchetti, Paulo F.R. Barahuna-Filho, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 31
Inhibition of O-GlcNAcylation Reduces Cell Viability and Autophagy and Increases Sensitivity to Chemotherapeutic Temozolomide in Glioblastoma
2023 · Amanda V. Leonel, Frederico Alisson-Silva, et al. · Cancers · 24
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Mesenchymal Stromal Cells From Emphysematous Donors and Their Extracellular Vesicles Are Unable to Reverse Cardiorespiratory Dysfunction in Experimental Severe Emphysema
2021 · Mariana A. Antunes, Cassia L. Braga, et al. · Frontiers in Cell and Developmental Biology · 24
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Eugenol disrupts Plasmodium falciparum intracellular development during the erythrocytic cycle and protects against cerebral malaria
2020 · Kesley A.O. Pontes, Leandro S. Silva, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 23
Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Activation of Bradykinin Receptors
2019 · Leandro S. Silva, Alessandro S. Pinheiro, et al. · Frontiers in Medicine · 23
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Gold nanoparticles reduce tubule-interstitial injury and proteinuria in a murine model of subclinical acute kidney injury
2023 · Rodrigo A.S. Peres, Rodrigo P. Silva-Aguiar, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 22
Role of the renin-angiotensin system in the development of severe COVID-19 in hypertensive patients
2020 · Rodrigo Pacheco Silva-Aguiar, Diogo Barros Peruchetti, et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 22
The renin–angiotensin–aldosterone system: Role in pathogenesis and potential therapeutic target in COVID‐19
2020 · Cássia L. Braga, Rodrigo P. Silva‐Aguiar, et al. · Pharmacology Research & Perspectives · 22
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The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury
2018 · Leandro S. Silva, Diogo B. Peruchetti, et al. · PLoS ONE · 22
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Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway
2019 · Douglas E. Teixeira, Diogo B. Peruchetti, et al. · PLoS ONE · 21
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Niclosamide attenuates lung vascular remodeling in experimental pulmonary arterial hypertension
2020 · Cássia Lisboa Braga, Nathane Santanna Felix, et al. · European Journal of Pharmacology · 19
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Subclinical Acute Kidney Injury in COVID-19: Possible Mechanisms and Future Perspectives
2022 · Rodrigo P. Silva-Aguiar, Douglas E. Teixeira, et al. · International Journal of Molecular Sciences · 18
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O-GlcNAcylation in Renal (Patho)Physiology
2022 · Rodrigo P. Silva-Aguiar, Diogo B. Peruchetti, et al. · International Journal of Molecular Sciences · 15
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SARS-CoV-2 spike protein inhibits megalin-mediated albumin endocytosis in proximal tubule epithelial cells
2022 · Rodrigo P. Silva-Aguiar, Douglas E. Teixeira, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 13
SARS-Cov-2 Replication in a Blood–Brain Barrier Model Established with Human Brain Microvascular Endothelial Cells Induces Permeability and Disables ACE2-Dependent Regulation of Bradykinin B1 Receptor
2025 · Sharton Vinicius Antunes Coelho, Gabriela Lisboa e Souza, et al. · International Journal of Molecular Sciences · 11
The angiotensin II/type 1 angiotensin II receptor pathway is implicated in the dysfunction of albumin endocytosis in renal proximal tubule epithelial cells induced by high glucose levels
2024 · Liz G. Afonso, Rodrigo P. Silva-Aguiar, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 11
The monoterpene 1,8-cineole prevents cerebral edema in a murine model of severe malaria
2022 · Edgleyson C. dos Santos, Leandro S. Silva, et al. · PLoS ONE · 10
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Surface megalin expression is a target to the inhibitory effect of bradykinin on the renal albumin endocytosis
2021 · Sarah A.S. Alves, Lucas S. Florentino, et al. · Peptides · 10
O-Linked GlcNAcylation mediates the inhibition of proximal tubule (Na++K+)ATPase activity in the early stage of diabetes mellitus
2023 · Rodrigo P. Silva-Aguiar, Douglas E. Teixeira, et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 9
Toll like receptor 4 mediates the inhibitory effect of SARS-CoV-2 spike protein on proximal tubule albumin endocytosis
2024 · Rodrigo P. Silva-Aguiar, Douglas E. Teixeira, et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 6
Works count: 39
Citation count: 582
H-index: 17
I10-index: 23
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