Author

Francesco DeGiacomo

Institution: Buck Institute for Research on Aging

Observed institution: Buck Institute for Research on Aging

OpenAlex ID: A5009719262

Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington's Disease Models

2010 · Melissa J. Leyva, Francesco DeGiacomo, et al. · Chemistry & Biology · 54

Posttranslational Modification of Ataxin-7 at Lysine 257 Prevents Autophagy-Mediated Turnover of an N-Terminal Caspase-7 Cleavage Fragment

2009 · Shona Mookerjee, Theodora Papanikolaou, et al. · Journal of Neuroscience · 53

Caspase-6 Activity in a BACHD Mouse Modulates Steady-State Levels of Mutant Huntingtin Protein But Is Not Necessary for Production of a 586 Amino Acid Proteolytic Fragment

2012 · Juliette Gafni, Theodora Papanikolaou, et al. · Journal of Neuroscience · 48

A Genome-Scale RNA–Interference Screen Identifies RRAS Signaling as a Pathologic Feature of Huntington's Disease

2012 · John P. Miller, Bridget E. Yates, et al. · PLoS Genetics · 46

Mass Spectrometric Identification of Novel Lysine Acetylation Sites in Huntingtin

2011 · Xin Cong, Jason M. Held, et al. · Molecular & Cellular Proteomics · 46

Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo

2015 · Robert O'Brien, Francesco DeGiacomo, et al. · Journal of Biological Chemistry · 21

Identification and Evaluation of Small Molecule Pan-Caspase Inhibitors in Huntington’s Disease Models

2013 · Melissa J. Leyva, Francesco DeGiacomo, et al. · Chemistry & Biology

Works count: 7

Citation count: 268

H-index: 6

I10-index: 6