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Ebbe Boedtkjer

Observed names: Boedtkjer Ebbe, Boedtkjer, E, Boedtkjer, E., Boedtkjer, Ebbe, Boedtkjer, Ebbe; id_orcid 0000-0002-5078-9279, Bødtkjer, Ebbe, E Boedtkjer, E Bødtkjer, E. Boedtkjer, E. Bødtkjer, Ebbe Boedtkjers, Ebbe Bødtkjer
Institution: Aarhus University
Observed institutions: Lithuanian University of Health Sciences, University of Leicester, Aarhus University, Aarhus University Hospital, Copenhagen University Hospital, William Harvey Research Institute, Regional Hospital Randers, Case Western Reserve University
ORCID: 0000-0002-5078-9279
Observed ORCID: 0000-0002-5078-9279
OpenAlex ID: A5009773928
The Acidic Tumor Microenvironment as a Driver of Cancer
2019 · Ebbe Boedtkjer, Stine F. Pedersen · Annual Review of Physiology · 1,223
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Regulation and roles of bicarbonate transporters in cancer
2014 · Andrej Gorbatenko, Christina W. Olesen, et al. · Frontiers in Physiology · 139
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Physiology, Pharmacology and Pathophysiology of the pH Regulatory Transport Proteins NHE1 and NBCn1: Similarities, Differences, and Implications for Cancer Therapy
2012 · E. Boedtkjer, L. Bunch, et al. · Current Pharmaceutical Design · 138
Disruption of Na + ,HCO 3 − Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca 2+ Sensitivity, and Hypertension Development in Mice
2011 · Ebbe Boedtkjer, Jeppe Praetorius, et al. · Circulation · 135
NBCn1 and NHE1 expression and activity in ΔNErbB2 receptor-expressing MCF-7 breast cancer cells: Contributions to pHi regulation and chemotherapy resistance
2010 · G. Lauritzen, M.B.F. Jensen, et al. · Experimental Cell Research · 120
Contribution of Na+,HCO3−‐cotransport to cellular pH control in human breast cancer: A role for the breast cancer susceptibility locus NBCn1 (SLC4A7)
2012 · Ebbe Boedtkjer, José M.A. Moreira, et al. · International Journal of Cancer · 119
How protons pave the way to aggressive cancers
2023 · Pawel Swietach, Ebbe Boedtkjer, et al. · Nature reviews. Cancer · 111
Disrupting Na+,HCO3–-cotransporter NBCn1 (Slc4a7) delays murine breast cancer development
2015 · S Lee, T V Axelsen, et al. · Oncogene · 93
NBCn1 (slc4a7) Mediates the Na + -Dependent Bicarbonate Transport Important for Regulation of Intracellular pH in Mouse Vascular Smooth Muscle Cells
2006 · Ebbe Boedtkjer, Jeppe Praetorius, et al. · Circulation Research · 88
Antibody-independent localization of the electroneutral Na+-HCO3− cotransporter NBCn1 (slc4a7) in mice
2007 · Ebbe Boedtkjer, Jeppe Praetorius, et al. · American Journal of Physiology-Cell Physiology · 86
The net acid extruders NHE1, NBCn1 and MCT4 promote mammary tumor growth through distinct but overlapping mechanisms
2018 · Anne Poder Andersen, Jacob Samsøe‐Petersen, et al. · International Journal of Cancer · 75
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Na+,HCO3 −-cotransport is functionally upregulated during human breast carcinogenesis and required for the inverted pH gradient across the plasma membrane
2014 · Soojung Lee, Marco Mele, et al. · Pflügers Archiv - European Journal of Physiology · 68
Intracellular pH in the Resistance Vasculature: Regulation and Functional Implications
2012 · Ebbe Boedtkjer, Christian Aalkjaer · Journal of Vascular Research · 66
Opening of Small and Intermediate Calcium-Activated Potassium Channels Induces Relaxation Mainly Mediated by Nitric-Oxide Release in Large Arteries and Endothelium-Derived Hyperpolarizing Factor in Small Arteries from Rat
2011 · Edgaras Stankevičius, Thomas Dalsgaard, et al. · Journal of Pharmacology and Experimental Therapeutics · 61
Na+,HCO3–-cotransporter NBCn1 (Slc4a7) accelerates ErbB2-induced breast cancer development and tumor growth in mice
2018 · Soojung Lee, Trine V. Axelsen, et al. · Oncogene · 60
Vaginal, Cervical and Uterine pH in Women with Normal and Abnormal Vaginal Microbiota
2021 · Malene Risager Lykke, Naja Becher, et al. · Pathogens · 56
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Cation‐Coupled Bicarbonate Transporters
2014 · Christian Aalkjaer, Ebbe Boedtkjer, et al. · Comprehensive physiology · 56
Vasomotion has chloride-dependency in rat mesenteric small arteries
2008 · D. M. Briggs Boedtkjer, V. V. Matchkov, et al. · Pflügers Archiv - European Journal of Physiology · 55
Ketone body 3-hydroxybutyrate elevates cardiac output through peripheral vasorelaxation and enhanced cardiac contractility
2023 · Casper Homilius, Jacob Marthinsen Seefeldt, et al. · Basic Research in Cardiology · 53
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NHE1 knockout reduces blood pressure and arterial media/lumen ratio with no effect on resting pHi in the vascular wall
2012 · Ebbe Boedtkjer, Helle H. Damkier, et al. · The Journal of Physiology · 52
Extracellular ʜ ᴄ ᴏ3 is sensed by mouse cerebral arteries: Regulation of tone by receptor protein tyrosine phosphatase γ
2015 · Ebbe Boedtkjer, Kristoffer B Hansen, et al. · Journal of Cerebral Blood Flow & Metabolism · 49
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Na + , HCO 3 − -cotransporter NBCn1 increases pH i gradients, filopodia, and migration of smooth muscle cells and promotes arterial remodelling
2016 · Ebbe Boedtkjer, Jacob F. Bentzon, et al. · Cardiovascular Research · 48
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Acid–base regulation and sensing: Accelerators and brakes in metabolic regulation of cerebrovascular tone
2017 · Ebbe Boedtkjer · Journal of Cerebral Blood Flow & Metabolism · 47
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Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer
2023 · Soojung Lee, Nicolai J. Toft, et al. · Breast Cancer Research · 45
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Acid-base transporters and pH dynamics in human breast carcinomas predict proliferative activity, metastasis, and survival
2021 · Nicolai J Toft, Trine V Axelsen, et al. · eLife · 41
Works count: 124
Citation count: 3,939
H-index: 31
I10-index: 61
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