Author

Merve Demir

Observed name: Demir, Merve

Institutions: Sanford Burnham Prebys Medical Discovery Institute, University of California, Davis

Observed institutions: Sanford Burnham Prebys Medical Discovery Institute, University of California, Davis

ORCID: 0000-0002-5721-8268

Observed ORCID: 0000-0002-5721-8268

OpenAlex ID: A5009937510

Structure, function and evolution of the Helix-hairpin-Helix DNA glycosylase superfamily: Piecing together the evolutionary puzzle of DNA base damage repair mechanisms

2021 · C.H. Trasviña-Arenas, Merve Demir, et al. · DNA repair · 41

Structural Basis for Finding OG Lesions and Avoiding Undamaged G by the DNA Glycosylase MutY

2019 · L. Peyton Russelburg, Valerie L. O’Shea Murray, et al. · ACS Chemical Biology · 37

Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism

2022 · Merve Demir, L Peyton Russelburg, et al. · Nucleic Acids Research · 32

Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its [4Fe-4S] cluster cofactor and active site required for DNA repair

2025 · Carlos H. Trasviña-Arenas, Upeksha C. Dissanayake, et al. · Nature Communications · 17

FSHing for DNA Damage: Key Features of MutY Detection of 8-Oxoguanine:Adenine Mismatches

2024 · Chandrima Majumdar, Merve Demir, et al. · Accounts of Chemical Research · 12

Structure of human MUTYH and functional profiling of cancer-associated variants reveal an allosteric network between its [4Fe-4S] cluster cofactor and active site required for DNA repair

2024 · Carlos H. Trasviña-Arenas, Upeksha C. Dissanayake, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 6

Structural basis for substrate binding, catalysis, and inhibition of cancer target mitochondrial creatine kinase by a covalent inhibitor

2025 · Merve Demir, Laura Koepping, et al. · Structure · 4

Structural Basis for Nucleobase Activation by the Adenine DNA Glycosylase MutY

2026 · L. Peyton Russelburg, Merve Demir, et al. · ChemBioChem

Uncompetitive Allosteric Inhibitor of Mitochondrial Creatine Kinase Prevents Binding and Release of Creatine by Stabilization of Loop Closure

2026 · Merve Demir, Chen-Ting Ma, et al. · Journal of Molecular Biology

Uncompetitive Allosteric Inhibitor of Mitochondrial Creatine Kinase Prevents Binding and Release of Creatine by Stabilization of Loop Closure

2026 · Merve Demir, Chen-Ting Ma, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Uncompetitive Allosteric Inhibitor of Mitochondrial Creatine Kinase Prevents Binding and Release of Creatine by Stabilization of Loop Closure

2026 · Merve Demir, Chen-Ting Ma, et al. · SSRN Electronic Journal

Structure and mechanism of the GO DNA repair enzyme MutY from bacteria and its human homolog MUTYH

2025 · Martin Horvath, L. Peyton Russelburg, et al. · Structural Dynamics

Structural Basis for Substrate Binding, Catalysis and Inhibition of Breast Cancer Target Mitochondrial Creatine Kinase by Covalent Inhibitor via Cryo-EM

2024 · Merve Demir, Laura Koepping, et al. · bioRxiv (Cold Spring Harbor Laboratory)

Works count: 15

Citation count: 150

H-index: 6

I10-index: 5