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Mark Basche

Observed names: Basche, M, M Basche, M. Basche
ORCID: 0009-0008-9861-6888
Observed ORCID: 0009-0008-9861-6888
OpenAlex ID: A5010114740
Restoration of visual function in advanced disease after transplantation of purified human pluripotent stem cell-derived cone photoreceptors
2021 · Joana Ribeiro, Christopher A. Procyk, et al. · Cell Reports · 134
Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors
2009 · Mei Hong Tan, Alexander J. Smith, et al. · Human Molecular Genetics · 119
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A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency
2018 · Julie Tordo, Claire O’Leary, et al. · Brain · 113
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Nanotube-like processes facilitate material transfer between photoreceptors
2021 · Aikaterini A Kalargyrou, Mark Basche, et al. · EMBO Reports · 89
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Successful Gene Therapy in Older Rpe65-Deficient Dogs Following Subretinal Injection of an Adeno-Associated Vector Expressing RPE65
2013 · Matthew J. Annear, Freya M. Mowat, et al. · Human Gene Therapy · 34
Neonatal brain-directed gene therapy rescues a mouse model of neurodegenerative CLN6 Batten disease
2019 · Sophia-Martha kleine Holthaus, Saul Herranz-Martin, et al. · Human Molecular Genetics · 31
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RNAi‐mediated suppression of vimentin or glial fibrillary acidic protein prevents the establishment of Müller glial cell hypertrophy in progressive retinal degeneration
2021 · Claire Hippert, Anna B. Graca, et al. · Glia · 29
Sustained and Widespread Gene Delivery to the Corneal Epithelium via In Situ Transduction of Limbal Epithelial Stem Cells, Using Lentiviral and Adeno-Associated Viral Vectors
2018 · Mark Basche, Daniel Kampik, et al. · Human Gene Therapy · 21
In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations
2017 · D Kampik, M Basche, et al. · Gene Therapy · 16
Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors
2009 · M. H. Tan, A. J. Smith, et al. · Human Molecular Genetics · 15
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Modulation of Contact Inhibition by ZO-1/ZONAB Gene Transfer—A New Strategy to Increase the Endothelial Cell Density of Corneal Grafts
2019 · Daniel Kampik, Mark Basche, et al. · Investigative Ophthalmology & Visual Science · 10
LRG1 Alters Pericyte Phenotype and Compromises Vascular Maturation
2025 · Alexandra E. Hoeh, Jui-Hsien Chang, et al. · Cells · 9
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Stromal Gene Therapy Mediates Prolonged Protection Against Corneal Neovascularization Induced by an Aggressive Angiogenic Insult
2025 · Mark Basche, Scott Robbie, et al. · Human Gene Therapy · 1
Lentivirus Mediated Interference With the ZO-1/ZONAB Pathway Induces Cell Cycle Progression in Human Corneal Endothelial Cells
2012 · Daniel Kampik, Mark Basche, et al. · Investigative Ophthalmology & Visual Science · 1
Cell-autonomous restoration of splicing homeostasis and RP11 phenotype in patient-derived RPE and retinal organoids by PRPF31.AAV gene therapy
2026 · Maria Elia, Valda Pauzuolyte, et al. · Nature Communications
Cell-autonomous restoration of splicing homeostasis and RP11 phenotype in patient-derived RPE and retinal organoids by PRPF31.AAV gene therapy
2026 · Majlinda Lako, Maria Elia, et al. · Research Square
Cell-autonomous restoration of splicing homeostasis and RP11 phenotype in patient-derived RPE and retinal organoids by PRPF31 .AAV gene therapy
2026 · Maria Elia, Valda Pauzuolyte, et al. · bioRxiv (Cold Spring Harbor Laboratory)
Cover Image, Volume 69, Issue 9
2021 · Claire Hippert, Anna B. Graca, et al. · Glia
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Lentiviral gene transfer of E2F2 induces regeneration of retinal pigment epithelium in situ
2016 · Daniel Kampik, Ulrich F. O. Luhmann, et al. · UCL Discovery (University College London)
Gene transfer of E2F2 induces in situ regeneration of retinal pigment epithelium
2016 · U. Luhmann, D. Kampik, et al. · Acta Ophthalmologica
256. A Novel Rationally Designed AAV Capsid Yields a Potent Neurotropic Gene Therapy Vector
2016 · Els Henckaerts, Julie Tordo, et al. · Molecular Therapy
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Gene therapy approaches to disease of the cornea and anterior chamber
2014 · Mark Basche · UCL Discovery (University College London)
Replication of retinal pigment epithelium can be induced by non integrating lentiviral gene transfer of E2F2
2011 · Luhmann, UFO, Kampik, D, et al. · UCL Discovery (University College London)
Non-integrating Lentiviral Gene Transfer Of E2F2 To Induce Corneal Endothelial Cell Replication
2011 · Daniel Kampik, Mark Basche, et al. · UCL Discovery (University College London)
A Strategy To Induce Corneal Endothelial Cell Replication Using A Reverse Transcription Defective Lentiviral Vector
2011 · Mark Basche, Daniel Kampik, et al. · Investigative Ophthalmology & Visual Science
Works count: 25
Citation count: 621
H-index: 10
I10-index: 11
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