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Samar A. El-Kalyoubi

Observed names: El-Kalyoubi, Samar, Elkalyoubi, Samar, S. A. El-Kalyoubi, S. El-Kalyoubi, Samar A. El‑Kalyoubi, Samar El-Kalyoubi, Samar El-kalyoubi, Samar ElKalyoubi, Samar Elkalyoubi, Samar El‐Kalyoubi
Observed institutions: Al-Azhar University, Zagazig University, Al-Azhar University, Al Azhar University, Port Said University, Jazan University
ORCID: 0000-0002-4648-5184
Observed ORCID: 0000-0002-4648-5184
OpenAlex ID: A5010124559
One-Pot Synthesis and Molecular Modeling Studies of New Bioactive Spiro-Oxindoles Based on Uracil Derivatives as SARS-CoV-2 Inhibitors Targeting RNA Polymerase and Spike Glycoprotein
2022 · Samar A. El-Kalyoubi, Ahmed Ragab, et al. · Pharmaceuticals · 70
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In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors
2021 · Eman A. Fayed, Eman S. Nosseir, et al. · Molecular Diversity · 53
Synthesis, In Silico Prediction and In Vitro Evaluation of Antimicrobial Activity, DFT Calculation and Theoretical Investigation of Novel Xanthines and Uracil Containing Imidazolone Derivatives
2021 · Samar El-Kalyoubi, Fatimah Agili, et al. · International Journal of Molecular Sciences · 43
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One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines
2017 · Samar A. El-Kalyoubi, Eman A. Fayed, et al. · Chemistry Central Journal · 38
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Design and synthesis of new spirooxindole candidates and their selenium nanoparticles as potential dual Topo I/II inhibitors, DNA intercalators, and apoptotic inducers
2023 · Samar El-Kalyoubi, Mohamed M. Khalifa, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 32
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Novel uracil derivatives depicted potential anticancer agents: In Vitro, molecular docking, and ADME study
2021 · Samar El-Kalyoubi, Fatimah Agili, et al. · Arabian Journal of Chemistry · 32
Synthesis and Evaluation of Antitumour Activities of Novel Fused Tri- and Tetracyclic Uracil Derivatives
2016 · Samar ElKalyoubi, Eman Fayed · Journal of Chemical Research · 32
Synthesis, In Silico Prediction and In Vitro Evaluation of Antitumor Activities of Novel Pyrido[2,3-d]pyrimidine, Xanthine and Lumazine Derivatives
2020 · Samar El-Kalyoubi, Fatimah Agili · Molecules · 30
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Design, Synthesis, and Biological Evaluation of New Potential Unusual Modified Anticancer Immunomodulators for Possible Non-Teratogenic Quinazoline-Based Thalidomide Analogs
2023 · Reda Mabrouk, Abdallah Abdallah, et al. · International Journal of Molecular Sciences · 24
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Design, Synthesis, and Anti-Proliferative Action of Purine/Pteridine-Based Derivatives as Dual Inhibitors of EGFR and BRAFV600E
2023 · Samar A. El-Kalyoubi, Hesham A. M. Gomaa, et al. · Pharmaceuticals · 24
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Synthesis, DFT calculations, and anti-proliferative evaluation of pyrimidine and selenadiazolopyrimidine derivatives as dual Topoisomerase II and HSP90 inhibitors
2023 · Samar El-Kalyoubi, Samiha A. El-Sebaey, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 22
A Novel Synthesis of Fused Uracils: Indenopyrimidopyridazines, Pyrimidopyridazines, and Pyrazolopyrimidines for Antimicrobial and Antitumor Evalution
2016 · Samar El-Kalyoubi, Fatimah Agili · Molecules · 21
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Synthesis, DNA Binding and Antiviral Activity of New Uracil, Xanthine, and Pteridine Derivatives
2007 · Osama I. El‐Sabbagh, Mohamed E. El‐Sadek, et al. · Archiv der Pharmazie · 21
Synthesis, In Vitro and In Silico Molecular Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to Thalidomide as Potent Antitubercular Agents
2025 · Shaker Youssif, Wael Shehta, et al. · SynOpen · 18
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Design and synthesis of uracil/thiouracil based quinoline scaffolds as topoisomerases I/II inhibitors for chemotherapy: A new hybrid navigator with DFT calculation
2023 · Samar El-Kalyoubi, Samar S. Elbaramawi, et al. · Bioorganic Chemistry · 15
Design, Synthesis and Antitumor Activity of Novel pyran-functionalized Uracil Derivatives: Docking Studies
2023 · Wael Shehta, Fatimah Agili, et al. · Future Medicinal Chemistry · 15
Novel Aminopyrimidine-2,4-diones, 2-Thiopyrimidine-4-ones, and 6-Arylpteridines as Dual-Target Inhibitors of BRD4/PLK1: Design, Synthesis, Cytotoxicity, and Computational Studies
2023 · Samar El-Kalyoubi, Samiha A. El-Sebaey, et al. · Pharmaceuticals · 14
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Novel pyrimidine Schiff bases and their selenium-containing nanoparticles as dual inhibitors of CDK1 and tubulin polymerase: design, synthesis, anti-proliferative evaluation, and molecular modelling
2023 · Samar El-Kalyoubi, Samiha A. El-Sebaey, et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 14
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Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent
2018 · Samar A. El-Kalyoubi · Chemistry Central Journal · 14
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Design and Synthesis of Novel Uracil-Linked Schiff Bases As Dual Histone Deacetylase Type II/topoisomerase Type I Inhibitors With Apoptotic Potential
2023 · Samar El-Kalyoubi, Samar S Elbaramawi, et al. · Future Medicinal Chemistry · 13
Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors
2022 · Samar A. El-Kalyoubi, Ehab S. Taher, et al. · Pharmaceuticals · 13
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Synthesis, Molecular Docking and Anticancer Activity of Some 5‐Aryl‐5,10‐dihydropyrido[2,3‐ d :6,5‐ d′ ]dipyrimidine‐2,4,6,8‐tetraone Derivatives and Pyrido[2,3‐ d ]pyrimidines
2022 · Basant Farag, Fatimah Agili, et al. · ChemistrySelect · 13
Novel 2-Thioxanthine and Dipyrimidopyridine Derivatives: Synthesis and Antimicrobial Activity
2015 · Samar El-kalyoubi, Fatmah Agili, et al. · Molecules · 12
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Synthesis and In Vitro Study of pyrimidine–phthalimide Hybrids As VEGFR2 Inhibitors With Antiproliferative Activity
2023 · Wael Shehta, Fatimah Agili, et al. · Future Medicinal Chemistry · 10
A Novel One-Pot and Efficient Procedure for Synthesis of New Fused Uracil Derivatives for DNA Binding
2015 · Bothaina A. Mousa, Ashraf H. Bayoumi, et al. · International Journal of Organic Chemistry · 10
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Works count: 58
Citation count: 681
H-index: 15
I10-index: 25
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