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Hwankyu Kang
Observed name:
H.J. Kang
Institution:
Qurient (South Korea)
Observed institutions:
Institut Pasteur Korea,
Qurient (South Korea)
OpenAlex ID:
A5010271373
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis
2013
·
Kevin Pethe
, Pablo Bifani
, et al.
·
Nature Medicine
·
608
Lead Optimization of a Novel Series of Imidazo[1,2-a]pyridine Amides Leading to a Clinical Candidate (Q203) as a Multi- and Extensively-Drug-Resistant Anti-tuberculosis Agent
2014
·
Sunhee Kang
, Ryang Yeo Kim
, et al.
·
Journal of Medicinal Chemistry
·
179
Safety, Tolerability, and Pharmacokinetics of Telacebec (Q203), a New Antituberculosis Agent, in Healthy Subjects
2021
·
Jeongjun Kim
, Jinho Choi
, et al.
·
Antimicrobial Agents and Chemotherapy
·
39
A Novel Selective Axl/Mer/CSF1R Kinase Inhibitor as a Cancer Immunotherapeutic Agent Targeting Both Immune and Tumor Cells in the Tumor Microenvironment
2022
·
Yeejin Jeon
, Hwankyu Kang
, et al.
·
Cancers
·
22
PDF
Safety, Tolerability, Pharmacokinetics, and Metabolism of Telacebec (Q203) for the Treatment of Tuberculosis: a Randomized, Placebo-Controlled, Multiple Ascending Dose Phase 1B Trial
2022
·
Jeongjun Kim
, Jinho Choi
, et al.
·
Antimicrobial Agents and Chemotherapy
·
16
Discovery of 4H-chromeno[2,3-d]pyrimidin-4-one derivatives as senescence inducers and their senescence-associated antiproliferative activities on cancer cells using advanced phenotypic assay
2020
·
Sangmi Oh
, Ji Young Lee
, et al.
·
European Journal of Medicinal Chemistry
·
10
PDF
Abstract 2255: Patient pharmacodynamic biomarker and pk evaluation results from an ongoing phase I dose-escalation study of q702, an axl, mer and csf1r kinase inhibitor in patients with advanced solid tumors
2023
·
Bae Jung Choi
, Devalingam Devalingam
, et al.
·
Cancer Research
·
4
Abstract 4139: Q702, selective Axl, Mer and CSF1R triple kinase inhibitor with dual potentials leading to tumor regression: Immuno-oncology therapy and targeted cancer therapy
2019
·
Yeong-In Yang
, Hwankyu Kang
, et al.
·
Cancer Research
·
4
A phase 1, multicenter, open-label, dose-escalation, safety, pharmacodynamic, pharmacokinetic study of Q702 with a cohort expansion at the RP2D in patients with advanced solid tumors.
2021
·
Angela Tatiana Alistar
, Anthony B. El-Khoueiry
, et al.
·
Journal of Clinical Oncology
·
2
Abstract 4974: Q702, selective Axl/Mer/CSF1R triple kinase inhibitor enhance the activity of immune checkpoint inhibitor by alteration of immunosuppressive tumor microenvironment
2020
·
Yeong-In Yang
, Hwankyu Kang
, et al.
·
Cancer Research
·
2
Abstract 4139: Q702, selective Axl, Mer and CSF1R triple kinase inhibitor with dual potentials leading to tumor regression: Immuno-oncology therapy and targeted cancer therapy
2019
·
Yeong-In Yang
, Hwankyu Kang
, et al.
·
Immunology
·
1
Abstract A009: Preclinical safety and efficacy QP101: A novel HER2-targeting dual payload ADC combining topoisomerase I (TOP1) and cyclin dependent kinase 7 (CDK7) inhibitors
2026
·
Kiyean Nam
, Hwankyu Kang
, et al.
·
Clinical Cancer Research
Abstract A052: Enhancing potency through synergy: QP101, a novel HER2 targeting dual payload ADC shows potent preclinical activities
2025
·
Yeong-In Yang
, Hwankyu Kang
, et al.
·
Molecular Cancer Therapeutics
645 A phase 1B/2, open-label study of Q702 in combination with intravenous pembrolizumab in patients with selected advanced solid tumors
2023
·
Seung-Tae Kim
, Hong Jae Chon
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
651 A phase 1, multicenter, open-label, dose-escalation, safety, pharmacodynamic, pharmacokinetic study of Q702 with a cohort expansion at the RP2D in patients with advanced solid tumors
2023
·
Devalingam Mahalingam
, Angela Alistar
, et al.
·
Journal for ImmunoTherapy of Cancer
PDF
Abstract A205: Q701, a selective Axl and Mer inhibitor as an immune checkpoint inhibitor
2018
·
Yeong-In Yang
, Hwankyu Kang
, et al.
·
Molecular Cancer Therapeutics
Abstract B162: Highly selective, orally available CDK7 inhibitor for cancer therapy
2018
·
Yeejin Jeon
, Donghoon Yu
, et al.
·
Molecular Cancer Therapeutics
Combined Effect of Cytotoxic T-lymphocyte antigen 4 (CTLA-4) and Programmed Cell Death 1 Ligand 1 (PD-L1) expression in tumor infiltrating lymphocytes on prognostic outcomes after resection of hepatocellular carcinoma
2017
·
J. An
, H.J. Kang
, et al.
·
Journal of Hepatology
Development of novel vaccine candidates for Mycobacterium tuberculosis involved in Phagosome Maturation Arrest (PMA)
2013
·
Sei Jin Park
, Jichan Jang
, et al.
·
한국실험동물학회 학술발표대회 논문집
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Works count:
19
Citation count:
887
H-index:
6
I10-index:
6
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