Author

James R. Lerma

Observed name: James R Lerma

Institution: University of Cincinnati

Observed institution: University of Cincinnati

OpenAlex ID: A5010571123

Bifunctional degraders of cyclin dependent kinase 9 (CDK9): Probing the relationship between linker length, properties, and selective protein degradation

2023 · Robert J. Tokarski, Chia M. Sharpe, et al. · European Journal of Medicinal Chemistry · 26

Examination of the Impact of Triazole Position within Linkers on Solubility and Lipophilicity of a CDK9 Degrader Series

2023 · Oluwatosin R. Ayinde, Chia Sharpe, et al. · ACS Medicinal Chemistry Letters · 10

Pyrimidine depletion enhances targeted and immune therapy combinations in acute myeloid leukemia

2024 · Ola A. Elgamal, Sydney Fobare, et al. · JCI Insight · 7

Mass Cytometry as a Tool for Investigating Senescence in Multiple Model Systems

2023 · Amina Abdul-Aziz, Raymond D. Devine, et al. · Cells · 6

PTPN11 Mutation Clonal Hierarchy in Acute Myeloid Leukemia

2024 · Sydney Fobare, Chia Sharpe, et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2

Characterization of the clonal hierarchy and immunophenotype of PTPN11 mutations in acute myeloid leukemia

2026 · Sydney Fobare, Chia Sharpe, et al. · JCI Insight · 1

Inhibition of Enhancer of Zeste Homolog 2 Induces Blast Differentiation, Impairs Engraftment and Prolongs Survival in Murine Models of Acute Myeloid Leukemia

2024 · Sydney Fobare, Ola A. Elgamal, et al. · Cancers · 1

A Novel Selective BCL2 Inhibitor with Limited Immune Suppression and Improved Safety Compared to Venetoclax

2023 · Chia Sharpe, Sara Elgamal, et al. · Blood · 1

Genome-Wide Methylome and Transcriptome Profiling of Acute Myeloid Leukemia Derived Bone Marrow Mesenchymal Cells Identify Age Group Specific Biological Pathway Dysregulation in the Bone Marrow Microenvironment of AML

2023 · Amina Abdul-Aziz, James R. Lerma, et al. · Blood · 1

Abstract 1542: Metabolic dysregulations of aged bone marrow mesenchymal cells in Acute Myeloid Leukemia reveal novel therapeutic targets

2025 · Mary E. Fuentes, Julia K. Christian, et al. · Cancer Research

Therapeutic Targeting of FLT3 Gate Keeper Mutation with E2082-0047 in Traditional and a Novel Immunocompetent Murine Adoptive Transfer Model of AML

2023 · Ola A. Elgamal, Juan Carlos Zapata, et al. · Blood

Development of a Fully Immunocompetent Adoptive Transfer In Vivo Model of Npm1 cA;Idh2 R140Q;Flt3 ITD AML

2023 · Chia Sharpe, Mariah Johnson, et al. · Blood

A Novel Inhibitor of FLT3 and Its Drug-Resistant Mutants with Superior Activity to Gilteritinib in Molm-13 Preclinical Acute Myeloid Leukemia Xenograft Model

2022 · Ola A Elgamal, James R Lerma, et al. · Blood

Works count: 13

Citation count: 55

H-index: 4

I10-index: 2