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Hongbo Xie

Concepts and applications of chemical fingerprint for hit and lead screening
2022 · Jingbo Yang, Yiyang Cai, et al. · Drug Discovery Today · 140
Discovery of [1,2,4]Triazolo[4,3-a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction
2019 · Mingze Qin, Qi Cao, et al. · Journal of Medicinal Chemistry · 97
CHG: A Systematically Integrated Database of Cancer Hallmark Genes
2020 · Denan Zhang, Diwei Huo, et al. · Frontiers in Genetics · 53
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Discovery of the programmed cell death-1/programmed cell death-ligand 1 interaction inhibitors bearing an indoline scaffold
2019 · Mingze Qin, Qi Cao, et al. · European Journal of Medicinal Chemistry · 53
Design and synthesis of novel 2-(4-(2-(dimethylamino)ethyl)-4H-1,2,4-triazol-3-yl)pyridines as potential antitumor agents
2014 · Mingze Qin, Xin Zhai, et al. · European Journal of Medicinal Chemistry · 36
Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb–Drug Interactions
2016 · Dan Liu, Jie Wu, et al. · Biological and Pharmaceutical Bulletin · 32
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Synthetic Lethality-based Identification of Targets for Anticancer Drugs in the Human Signaling Network
2018 · Lei Liu, Xiujie Chen, et al. · Scientific Reports · 30
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Designing of dual inhibitors for GSK-3β and CDK5: Virtual screening andin vitrobiological activities study
2017 · Hongbo Xie, Haixia Wen, et al. · Oncotarget · 30
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Synthesis and antiproliferative activity of 6,7-disubstituted-4-phenoxyquinoline derivatives bearing the 2-oxo-4-chloro-1,2-dihydroquinoline-3-carboxamide moiety
2016 · Qidong Tang, Xin Zhai, et al. · Bioorganic & Medicinal Chemistry Letters · 27
In silico drug repositioning for the treatment of Alzheimer's disease using molecular docking and gene expression data
2016 · Hongbo Xie, Haixia Wen, et al. · RSC Advances · 23
Novel hydrazone moiety-bearing aminopyrimidines as selective inhibitors of epidermal growth factor receptor T790M mutant
2015 · Mingze Qin, Tingting Wang, et al. · European Journal of Medicinal Chemistry · 17
Identification of breast cancer recurrence risk factors based on functional pathways in tumor and normal tissues
2016 · Xiujie Chen, Lei Liu, et al. · Oncotarget · 14
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In vitroinhibition of UGT1A3, UGT1A4 by ursolic acid and oleanolic acid and drug–drug interaction risk prediction
2016 · Hongbo Xie, Jie Wu, et al. · Xenobiotica · 12
Some insights into the binding mechanism of the GABAA receptor: a combined docking and MM-GBSA study
2013 · Hong-Bo Xie, Yu Sha, et al. · Journal of Molecular Modeling · 11
Identification of Early Warning Signals at the Critical Transition Point of Colorectal Cancer Based on Dynamic Network Analysis
2020 · Lei Liu, Zhuo Shao, et al. · Frontiers in Bioengineering and Biotechnology · 10
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Molecular dynamics investigation of Cl− transport through the closed and open states of the 2α12β2γ2 GABAA receptor
2013 · Hong-Bo Xie, Jian Wang, et al. · Biophysical Chemistry · 10
Decoding temporal heterogeneity in NSCLC through machine learning and prognostic model construction
2024 · Junpeng Cheng, Meizhu Xiao, et al. · World Journal of Surgical Oncology · 8
N6-methyladenosine participates in mouse hippocampus neurodegeneration via PD-1/PD-L1 pathway
2023 · Wen Hu, Hongbo Xie, et al. · Frontiers in Neuroscience · 7
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Precision treatment exploration of breast cancer based on heterogeneity analysis of lncRNAs at the single-cell level
2021 · Yan Zhang, Denan Zhang, et al. · BMC Cancer · 7
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New insights for precision treatment of glioblastoma from analysis of single-cell lncRNA expression
2021 · Qingkang Meng, Yan Zhang, et al. · Journal of Cancer Research and Clinical Oncology · 7
Biological evaluation and energetic analyses of novel GSK‐3 β inhibitors
2017 · Denan Zhang, Lei Liu, et al. · Journal of Cellular Biochemistry · 6
IGSA: Individual Gene Sets Analysis, including Enrichment and Clustering
2016 · Lingxiang Wu, Xiujie Chen, et al. · PLoS ONE · 6
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Predicting drug synergy using a network propagation inspired machine learning framework
2024 · Qing Jin, Xianze Zhang, et al. · Briefings in Functional Genomics · 5
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Integrating multiple machine learning algorithms for prognostic prediction of gastric cancer based on immune-related lncRNAs
2023 · Guoqi Li, Diwei Huo, et al. · Frontiers in Genetics · 5
Mechanisms of organotropism in breast cancer and predicting metastasis to distant organs using deep learning
2025 · Meizhu Xiao, Zhijin Fu, et al. · Discover Oncology · 4
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Works count: 41
Citation count: 662
H-index: 12
I10-index: 16
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