Author

Tatsuya Okuzumi

Observed names: T. OKUZUMI, 奥住竜哉, 竜哉奥住

Observed institutions: Tokyo Institute of Technology, Howard Hughes Medical Institute, University of California, San Francisco, Ajinomoto (Japan)

ORCID: 0000-0001-5839-6958

Observed ORCID: 0000-0001-5839-6958

OpenAlex ID: A5010724729

Inhibitor hijacking of Akt activation

2009 · Tatsuya Okuzumi, Dorothea Fiedler, et al. · Nature Chemical Biology · 302

Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody–Drug Conjugates

2024 · Tomohiro Watanabe, Naoko Arashida, et al. · Journal of Medicinal Chemistry · 73

AJICAP Second Generation: Improved Chemical Site-Specific Conjugation Technology for Antibody–Drug Conjugate Production

2023 · Tomohiro Fujii, Yutaka Matsuda, et al. · Bioconjugate Chemistry · 66

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Chemical Site-Specific Conjugation Platform to Improve the Pharmacokinetics and Therapeutic Index of Antibody–Drug Conjugates

2021 · Yutaka Matsuda, Takuya Seki, et al. · Molecular Pharmaceutics · 64

A Purification Strategy Utilizing Hydrophobic Interaction Chromatography to Obtain Homogeneous Species from a Site-Specific Antibody Drug Conjugate Produced by AJICAP™ First Generation

2020 · Yutaka Matsuda, Monica Leung, et al. · Antibodies · 37

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AJICAP-M: Traceless Affinity Peptide Mediated Conjugation Technology for Site-Selective Antibody–Drug Conjugate Synthesis

2024 · Yutaka Matsuda, Natsuki Shikida, et al. · Organic Letters · 30

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Chromatographic analysis of site-specific antibody-drug conjugates produced by AJICAP first-generation technology using a recombinant FcγIIIa receptor-ligand affinity column

2021 · Yutaka Matsuda, Atis Chakrabarti, et al. · Journal of Chromatography B · 28

Gram-Scale Antibody–Drug Conjugate Synthesis by Site-Specific Chemical Conjugation: AJICAP First Generation

2019 · Yutaka Matsuda, Kei Yamada, et al. · Organic Process Research & Development · 28

Synthesis and evaluation of indazole based analog sensitive Akt inhibitors

2010 · Tatsuya Okuzumi, Gregory S Ducker, et al. · Molecular BioSystems · 20

Efficient Solid-Phase Synthesis of Diverse 2-Aminoquinazolin-4-ones from Resin-Bound Anilines

2003 · Shingo Makino, Tatsuya Okuzumi, et al. · Journal of Combinatorial Chemistry · 18

Efficient solid-phase synthesis of quinazoline-2,4-diones with various substituents on aromatic rings

2003 · Tatsuya Okuzumi, Eiji Nakanishi, et al. · Tetrahedron · 17

Efficient solid-phase synthesis of diverse 1,2,3-benzotriazin-4-ones using tert-butyl nitrite

2003 · Tatsuya Okuzumi, Eiji Nakanishi, et al. · Tetrahedron Letters · 15

Stereochemistry of the reduction of 24-ethyldesmosterol to sitosterol in tissue cultures of Oryza sativa

1998 · Yoshinori Fujimoto, Naoko Sato, et al. · Bioorganic & Medicinal Chemistry Letters · 11

Biological Evaluation of Maytansinoid-Based Site-Specific Antibody-Drug Conjugate Produced by Fully Chemical Conjugation Approach: AJICAP®

2022 · Takuya Seki, Kei Yamada, et al. · Frontiers in Bioscience-Landmark · 10

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Solid-phase synthesis of 2-substituted-3-(substituted sulfanyl)-1,2,4-benzothiadiazine 1,1-dioxide library

2002 · Shingo Makino, Tatsuya Okuzumi, et al. · Tetrahedron Letters · 10

Mechanism of the double bond isomerization from Δ24(28) to Δ24(25) in sitosterol biosynthesis in higher plants

1999 · Tatsuya Okuzumi, Noriyuki Hara, et al. · Tetrahedron Letters · 10

Mechanism of the second methylation in sitosterol side-chain biosynthesis in higher plants: metabolic fate of 28-hydrogens of 24-methylenecholesterol in Morus alba cell cultures

2000 · Tatsuya Okuzumi, Yuko Kaji, et al. · Tetrahedron Letters · 7

AJICAP®: Chemical site-specific conjugation technology for next-generation ADC

2021 · Tatsuya Okuzumi · The Chemical Society of Japan

AJICAP™: Development of a Chemical Site-Specific Conjugation Technology for Antibody-Drug Conjugates

2020 · Kei Yamada, Tatsuya Okuzumi · Journal of Synthetic Organic Chemistry Japan

分科会bグループ発表会技術マネジメント/技術の体系化 (特集研究・技術人材の育成) -- (企業研究会第11期研究・技術人材開発フォーラム)

2015 · 伸一郎川上, 竜哉奥住, et al. · BuR - Business Research

医薬品産業の過去・現在・未来

2014 · 奥住竜哉 · ファルマシア

平賀源内に学ぶイノベーターになる方法, 出川通著, 言視舎, 四六判, 207頁, 1,575円

2013 · 竜哉奥住 · ファルマシア

2012 · 竜哉奥住 · ファルマシア

73(p-57) 植物ステロール側鎖生合成機構の解析 : C-28位における反応の立体化学(ポスター発表の部)

2002 · 竜哉奥住, 武史小網, et al. · 天然有機化合物討論会講演要旨集

ChemInform Abstract: Stereochemistry of the Reduction of 24‐Ethyldesmosterol to Sitosterol in Tissue Cultures of Oryza sativa.

1998 · Y. FUJIMOTO, N. SATO, et al. · ChemInform

Works count: 25

Citation count: 746

H-index: 12

I10-index: 16