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Leduo Zhang

Observed names: Leduo zhang, Zhang Leduo
ORCID: 0000-0002-0877-8621
Observed ORCID: 0000-0002-0877-8621
OpenAlex ID: A5011440617
A Chemical Tuned Strategy to Develop Novel Irreversible EGFR-TK Inhibitors with Improved Safety and Pharmacokinetic Profiles
2014 · Guangxin Xia, Wenteng Chen, et al. · Journal of Medicinal Chemistry · 80
Discovery and Characterization of RP03707: A Highly Potent and Selective KRAS G12D PROTAC
2025 · Xiang Ji, Huanping Li, et al. · Journal of Medicinal Chemistry · 29
Discovery of 6-(2-(dimethylamino)ethyl)-N-(5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole-6-yl)pyrimidin-2-yl)-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine as a highly potent cyclin-dependent kinase 4/6 inhibitor for treatment of cancer
2019 · Chen Shi, Qian Wang, et al. · European Journal of Medicinal Chemistry · 25
Discovery of a novel series of imidazo[1′,2’:1,6]pyrido[2,3-d]pyrimidin derivatives as potent cyclin-dependent kinase 4/6 inhibitors
2020 · Chen Shi, Qian Wang, et al. · European Journal of Medicinal Chemistry · 22
Discovery and optimization of a series of imidazo[4,5-b]pyrazine derivatives as highly potent and exquisitely selective inhibitors of the mesenchymal–epithelial transition factor (c-Met) protein kinase
2016 · Fei Zhao, Jing Zhang, et al. · Bioorganic & Medicinal Chemistry · 20
Classification of Fabric Defect Based on PSO-BP Neural Network
2008 · Suyi Liu, Jingjing Liu, et al. · International Conference on Genetic and Evolutionary Computing · 11
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor
2019 · Leduo Zhang, Yu Mao, et al. · European Journal of Drug Metabolism and Pharmacokinetics · 8
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SPH3127: A Phase I, Randomized, Double-Blind, Placebo-Controlled Trial
2021 · Shan Jing, Ranchi Xu, et al. · Clinical Therapeutics · 7
Textile Pattern Generation Technique Based on Quasi-Regular Pattern Theory and Their Transform
2008 · Liu Suyi, Zhang Leduo · Pacific-Asia Workshop on Computational Intelligence and Industrial Application · 7
Abstract 6050: Targeting KRAS G12D mutant tumors with the PROTAC degrader RP03707
2024 · Xiang Ji, Huanping Li, et al. · Cancer Research · 5
Evaluation of preclinical safety profile of SPH3127, a direct renin inhibitor, after 28-day repeated oral administration in Sprague-Dawley rats and cynomolgus monkeys
2019 · Yu Mao, Leduo zhang, et al. · Regulatory Toxicology and Pharmacology · 5
Abstract 1662: Preclinical studies of RP04340: an orally available and potent PROTAC compound targeting KRAS G12C/D/V mutant tumors
2025 · Xiang Ji, Chao Deng, et al. · Cancer Research · 3
Detection and Classification of Fabric Color Difference Based on Fuzzy Artificial Neural Network
2008 · Liu Suyi, Wan Qian, et al. · International Symposium on Computational Intelligence and Design · 3
Textile Pattern Design Based on Hamilton Function Transformation
2009 · Liu Suyi, Zhang Leduo · International Workshop on Education Technology and Computer Science · 2
Abstract 4288: Discovery of a small molecule inhibitor of ADAR1 for cancer immunotherapy
2025 · Zijun Chen, Liqiang Shen, et al. · Cancer Research · 1
The Generation System of Textile Pattern Based on L-Systems
2018 · Suyi Liu, Leduo Zhang, et al. · Proceedings of the 8th International Conference on Management and Computer Science (ICMCS 2018) · 1
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Erratum to “Discovery and optimization of a series of imidazo[4,5-b]pyrazine derivatives as highly potent and exquisitely selective inhibitors of the mesenchymal–epithelial transition factor (c-Met) protein kinase” [Bioorg. Med. Chem. 24 (2016) 4281–4290]
2017 · Fei Zhao, Jing Zhang, et al. · Bioorganic & Medicinal Chemistry · 1
Fabric Color Difference Identification Based on Fuzzy Membership Criterion
2008 · Liu Suyi, Wan Qian, et al. · Intelligent Information Technology Application · 1
Discovery and Characterization of RP04340 : A Highly Potent and Orally Active Pan-KRAS PROTAC Degrader
2026 · Xiang Ji, Yuening Du, et al. · Journal of Medicinal Chemistry
Works count: 19
Citation count: 231
H-index: 7
I10-index: 6
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